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NK-92

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NK-92細胞是一種人類自然殺傷細胞(NK細胞)的細胞系,分離自一位50歲的男性非霍奇金氏淋巴瘤病人[1]。NK-92能分泌腫瘤壞死因子(TNF-α)和γ-干擾素(IFN-γ)等細胞因子,還能通過穿孔素顆粒酶來攻擊被細菌感染的細胞[2]

參考資料

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  1. ^ ong, J., Maki, G., and Klingemann, H-G. (1994). 「Characterization of a human cell line (NK-92) with phenotypical and functional characteristics of activated natural killer cells」. Leukemia; 8: 652-58.
  2. ^ Paul S, Lal G. The Molecular Mechanism of Natural Killer Cells Function and Its Importance in Cancer Immunotherapy. Frontiers in Immunology. 2017, 8: 1124. PMC 5601256可免費查閱. PMID 28955340. doi:10.3389/fimmu.2017.01124可免費查閱. 

外部連結

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