Pages that link to "Q74198977"
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The following pages link to mdmx is a negative regulator of p53 activity in vivo (Q74198977):
Displaying 50 items.
- Turning the RING domain protein MdmX into an active ubiquitin-protein ligase (Q24295055) (← links)
- Regulation of MDMX nuclear import and degradation by Chk2 and 14-3-3. (Q24306287) (← links)
- 14-3-3gamma binds to MDMX that is phosphorylated by UV-activated Chk1, resulting in p53 activation (Q24306380) (← links)
- Phosphorylation of MDMX mediated by Akt leads to stabilization and induces 14-3-3 binding (Q24313228) (← links)
- MDMX regulation of p53 response to ribosomal stress (Q24316958) (← links)
- MDM4 (MDMX) localizes at the mitochondria and facilitates the p53-mediated intrinsic-apoptotic pathway (Q24337839) (← links)
- DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation (Q24338364) (← links)
- DNA damage induces MDMX nuclear translocation by p53-dependent and -independent mechanisms (Q24540261) (← links)
- Deubiquitinating enzyme regulation of the p53 pathway: A lesson from Otub1 (Q27003153) (← links)
- Crystal Structures of Human MdmX (HdmX) in Complex with p53 Peptide Analogues Reveal Surprising Conformational Changes (Q27653453) (← links)
- The Double Role of p53 in Cancer and Autoimmunity and Its Potential as Therapeutic Target (Q28071415) (← links)
- Role of MDM2 and MDMX in DNA repair (Q28079939) (← links)
- Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification (Q28512492) (← links)
- TP53 copy number expansion is associated with the evolution of increased body size and an enhanced DNA damage response in elephants (Q28597702) (← links)
- MDM2 and MDMX: Alone and together in regulation of p53 (Q28611422) (← links)
- Regulating the p53 pathway: in vitro hypotheses, in vivo veritas (Q29615658) (← links)
- p53 ubiquitination: Mdm2 and beyond (Q29619502) (← links)
- MDM4 (MDMX) and its Transcript Variants. (Q30380283) (← links)
- Predicted functions of MdmX in fine-tuning the response of p53 to DNA damage (Q33533321) (← links)
- Tumorigenesis promotes Mdm4-S overexpression (Q33688440) (← links)
- Regulation of p53-MDMX interaction by casein kinase 1 alpha (Q33925248) (← links)
- Smad ubiquitylation regulatory factor 1/2 (Smurf1/2) promotes p53 degradation by stabilizing the E3 ligase MDM2. (Q34003810) (← links)
- p53 at a glance (Q34029735) (← links)
- The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor (Q34030117) (← links)
- ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage (Q34116228) (← links)
- Spontaneous tumorigenesis in mice overexpressing the p53-negative regulator Mdm4 (Q34134327) (← links)
- Constant p53 pathway inactivation in a large series of soft tissue sarcomas with complex genetics (Q34162527) (← links)
- Ribosomal protein S27-like is a physiological regulator of p53 that suppresses genomic instability and tumorigenesis (Q34178921) (← links)
- Tissue-specific differences of p53 inhibition by Mdm2 and Mdm4. (Q34233412) (← links)
- Mechanism of p53 stabilization by ATM after DNA damage (Q34296531) (← links)
- Phosphorylation of Ser312 contributes to tumor suppression by p53 in vivo (Q34320401) (← links)
- Synergistic roles of Mdm2 and Mdm4 for p53 inhibition in central nervous system development (Q34480087) (← links)
- Prospects on strategies for therapeutically targeting oncogenic regulatory factors by small-molecule agents (Q34554617) (← links)
- Critical contribution of the MDM2 acidic domain to p53 ubiquitination (Q35107890) (← links)
- Regulation of apoptosis: the ubiquitous way (Q35118566) (← links)
- The p53 inhibitors MDM2/MDMX complex is required for control of p53 activity in vivo (Q35122947) (← links)
- Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability (Q35123240) (← links)
- Stochastic modeling and simulation of the p53-MDM2/MDMX loop (Q35140857) (← links)
- MDM2 promotes ubiquitination and degradation of MDMX (Q35161842) (← links)
- miR-34 and p53: New Insights into a Complex Functional Relationship (Q35692651) (← links)
- Haploinsufficiency of Mdm2 and Mdm4 in tumorigenesis and development (Q35950132) (← links)
- Caspase-dependent degradation of MDMx/MDM4 cell cycle regulatory protein in amyloid β-induced neuronal damage (Q36372974) (← links)
- The Roles of MDM2 and MDMX Phosphorylation in Stress Signaling to p53. (Q36387600) (← links)
- MdmX promotes bipolar mitosis to suppress transformation and tumorigenesis in p53-deficient cells and mice (Q36483408) (← links)
- Regulation of MDMX expression by mitogenic signaling (Q36498007) (← links)
- Amplification of Mdmx (or Mdm4) directly contributes to tumor formation by inhibiting p53 tumor suppressor activity (Q36732343) (← links)
- MdmX regulates transformation and chromosomal stability in p53-deficient cells (Q37276428) (← links)
- Dual function of MDM2 and MDMX toward the tumor suppressors p53 and RB. (Q37422728) (← links)
- The Zn-finger domain of MdmX suppresses cancer progression by promoting genome stability in p53-mutant cells (Q37426771) (← links)
- A polymorphic variant in human MDM4 associates with accelerated age of onset of estrogen receptor negative breast cancer (Q37494380) (← links)