Pages that link to "Q73538051"
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The following pages link to Farnesyltransferase inhibitors: antineoplastic mechanism and clinical prospects (Q73538051):
Displaying 50 items.
- Golgi targeting of human guanylate-binding protein-1 requires nucleotide binding, isoprenylation, and an IFN-gamma-inducible cofactor (Q24529563) (← links)
- RhoB alteration is necessary for apoptotic and antineoplastic responses to farnesyltransferase inhibitors (Q24552386) (← links)
- RhoB is required to mediate apoptosis in neoplastically transformed cells after DNA damage (Q24628907) (← links)
- The yeast DHHC cysteine-rich domain protein Akr1p is a palmitoyl transferase (Q24672871) (← links)
- The farnesyl transferase inhibitor RPR-130401 does not alter radiation susceptibility in human tumor cells with a K-Ras mutation in spite of large changes in ploidy and lamin B distribution (Q24805139) (← links)
- Discovery of potent imidazole and cyanophenyl containing farnesyltransferase inhibitors with improved oral bioavailability (Q27641005) (← links)
- Aberrant growth and differentiation of oligodendrocyte progenitors in neurofibromatosis type 1 mutants (Q28591548) (← links)
- LC-MS/MS determination of a farnesyl transferase inhibitor in human plasma and urine (Q33425995) (← links)
- Phase II trial of tipifarnib and radiation in children with newly diagnosed diffuse intrinsic pontine gliomas (Q33825938) (← links)
- BAR the door: cancer suppression by amphiphysin-like genes (Q33870256) (← links)
- The pursuit of optimal outcomes in cancer therapy in a new age of rationally designed target-based anticancer agents (Q34112975) (← links)
- Heterotrimeric G-protein betagamma-dimers in growth and differentiation (Q34226052) (← links)
- Oligonucleotide treatment of ras-induced tumors in nude mice (Q34300042) (← links)
- Cancer therapy. New strategies and treatment modalities for optimizing patient outcomes (Q34346781) (← links)
- Farnesyl protein transferase inhibitors as targeted therapies for hematologic malignancies (Q34346795) (← links)
- Searching new targets for anticancer drug design: the families of Ras and Rho GTPases and their effectors (Q34348449) (← links)
- Organelle-specific initiation of cell death pathways (Q34443559) (← links)
- Evolving therapies: farnesyltransferase inhibitors (Q34457426) (← links)
- HMG-CoA reductase inhibitors and the malignant cell: the statin family of drugs as triggers of tumor-specific apoptosis (Q34605246) (← links)
- Single cell Ras-GTP analysis reveals altered Ras activity in a subpopulation of neurofibroma Schwann cells but not fibroblasts (Q34734319) (← links)
- A farnesylated G-protein suppresses Akt phosphorylation in INS 832/13 cells and normal rat islets: Regulation by pertussis toxin and PGE2 (Q34884341) (← links)
- Combination therapy with imatinib mesylate (STI571): synopsis of in vitro studies (Q34929081) (← links)
- Farnesyl transferase inhibitors in myeloid malignancies (Q35158942) (← links)
- Therapeutic efficacy of prenylation inhibitors in the treatment of myeloid leukemia (Q35186888) (← links)
- Cytotoxicity of farnesyltransferase inhibitors in lymphoid cells mediated by MAPK pathway inhibition and Bim up-regulation. (Q35525553) (← links)
- Pharmacological targeting of ICAM-1 signaling in brain endothelial cells: potential for treating neuroinflammation (Q36166116) (← links)
- The Akt/PKB pathway: molecular target for cancer drug discovery (Q36313193) (← links)
- Reversal of the Ras-induced transformed phenotype by HR12, a novel ras farnesylation inhibitor, is mediated by the Mek/Erk pathway (Q36360393) (← links)
- Phase I trial of tipifarnib in children with newly diagnosed intrinsic diffuse brainstem glioma (Q36926772) (← links)
- In Vitro Apoptotic Effects of Farnesyltransferase blockade in Acute Myeloid Leukemia Cells (Q37432558) (← links)
- Phase 1/1b study of lonafarnib and temozolomide in patients with recurrent or temozolomide refractory glioblastoma (Q37727000) (← links)
- Altered apoptotic responses in neurons lacking RhoB GTPase (Q39205118) (← links)
- Farnesyl transferase inhibitor treatment of breast cancer cells leads to altered RhoA and RhoC GTPase activity and induces a dormant phenotype (Q39658220) (← links)
- Activation of Rheb, but not of mTORC1, impairs spine synapse morphogenesis in tuberous sclerosis complex (Q40187301) (← links)
- Role for RhoB and PRK in the suppression of epithelial cell transformation by farnesyltransferase inhibitors (Q40667915) (← links)
- Homeobox gene Cdx1 regulates Ras, Rho and PI3 kinase pathways leading to transformation and tumorigenesis of intestinal epithelial cells. (Q40791040) (← links)
- Rho Family GTPase modification and dependence on CAAX motif-signaled posttranslational modification (Q42434602) (← links)
- Mitogen-responsive expression of RhoB is regulated by RNA stability (Q42795863) (← links)
- Synthesis and biological evaluation of 4-[3-biphenyl-2-yl-1-hydroxy-1-(3-methyl-3H-imidazol-4-yl)-prop-2-ynyl]-1-yl-benzonitrile as novel farnesyltransferase inhibitor (Q42803818) (← links)
- Synthesis and biological evaluation of 4-[(3-Methyl-3 H -imidazol-4-yl)-(2-phenylethynyl-benzyloxy)-methyl]-benzonitrile as novel farnesyltransferase inhibitor (Q42835076) (← links)
- Anions modulate the potency of geranylgeranyl-protein transferase I inhibitors (Q43556623) (← links)
- 2-Arylindole-3-acetamides: FPP-competitive inhibitors of farnesyl protein transferase (Q43569138) (← links)
- Small GTP binding protein Ras contributes to norepinephrine-induced mitogenesis of vascular smooth muscle cells (Q43607162) (← links)
- Blocking protein geranylgeranylation is essential for lovastatin-induced apoptosis of human acute myeloid leukemia cells (Q43714923) (← links)
- Non-thiol farnesyltransferase inhibitors: N-(4-Acylamino-3-benzoylphenyl)-4-nitrocinnamic acid amides (Q43821528) (← links)
- Non-thiol farnesyltransferase inhibitors: structure-activity relationships of benzophenone-based bisubstrate analogue farnesyltransferase inhibitors (Q43869102) (← links)
- Coupling of isoprenoid triflates with organoboron nucleophiles: synthesis and biological evaluation of geranylgeranyl diphosphate analogues (Q43911092) (← links)
- Actin' up: RhoB in cancer and apoptosis (Q43924647) (← links)
- Aromatic farnesyl diphosphate analogues: vinyl triflate-mediated synthesis and preliminary enzymatic evaluation (Q43981495) (← links)
- Synthesis and evaluation of a novel series of farnesyl protein transferase inhibitors as non-peptidic CAAX tetrapeptide analogues (Q44385176) (← links)