Pages that link to "Q73119749"

The following pages link to Cytotoxic mechanism of 6-thioguanine: hMutSalpha, the human mismatch binding heterodimer, binds to DNA containing S6-methylthioguanine (Q73119749):

Displaying 42 items.

• 6-thioguanine selectively kills BRCA2-defective tumors and overcomes PARP inhibitor resistance (Q24599364) (← links)
• Mutations affecting a putative MutLalpha endonuclease motif impact multiple mismatch repair functions (Q24646969) (← links)
• Effect of 6-thioguanine on the stability of duplex DNA (Q24805824) (← links)
• Mercaptopurine/Methotrexate maintenance therapy of childhood acute lymphoblastic leukemia: clinical facts and fiction (Q27023839) (← links)
• Structural effect of the anticancer agent 6-thioguanine on duplex DNA (Q27640490) (← links)
• Structure and specificity of the vertebrate anti-mutator uracil-DNA glycosylase SMUG1 (Q27641492) (← links)
• The main role of human thymine-DNA glycosylase is removal of thymine produced by deamination of 5-methylcytosine and not removal of ethenocytosine (Q28218523) (← links)
• Therapy-related myeloid neoplasms: pathobiology and clinical characteristics (Q28386366) (← links)
• The effect of 6-thioguanine on alternative splicing and antisense-mediated exon skipping treatment for duchenne muscular dystrophy (Q28484390) (← links)
• Assessment of Thiopurine-based drugs according to Thiopurine S-methyltransferase genotype in patients with Acute Lymphoblastic Leukemia (Q28612763) (← links)
• Liquid chromatography-mass spectrometry for measuring deoxythioguanosine in DNA from thiopurine-treated patients (Q28829483) (← links)
• 6-mercaptopurine dosage and pharmacokinetics influence the degree of bone marrow toxicity following high-dose methotrexate in children with acute lymphoblastic leukemia (Q32173689) (← links)
• Possible carcinogenic effect of 6-mercaptopurine on bone marrow stem cells: relation to thiopurine metabolism (Q33874582) (← links)
• Genetic analysis of mouse embryonic stem cells bearing Msh3 and Msh2 single and compound mutations (Q33961252) (← links)
• LC-MS/MS coupled with stable isotope dilution method for the quantification of 6-thioguanine and S(6)-methylthioguanine in genomic DNA of human cancer cells treated with 6-thioguanine (Q34070112) (← links)
• Alkyltransferase-like protein (eATL) prevents mismatch repair-mediated toxicity induced by O6-alkylguanine adducts in Escherichia coli. (Q34241602) (← links)
• 6-Thioguanine and S⁶-methylthioguanine are mutagenic in human cells (Q34440523) (← links)
• Epidemiology of therapy-related myeloid neoplasms after treatment for pediatric acute lymphoblastic leukemia in the nordic countries (Q35040001) (← links)
• The Krüppel-associated box repressor domain induces reversible and irreversible regulation of endogenous mouse genes by mediating different chromatin states (Q35089043) (← links)
• Role of DNA mismatch repair in apoptotic responses to therapeutic agents (Q35910747) (← links)
• Systemic Exposure to Thiopurines and Risk of Relapse in Children With Acute Lymphoblastic Leukemia: A Children's Oncology Group Study (Q36031471) (← links)
• Mechanisms of therapy-related carcinogenesis (Q36315585) (← links)
• Effects of 6-thioguanine and S6-methylthioguanine on transcription in vitro and in human cells (Q36436001) (← links)
• The multifaceted mismatch-repair system (Q36448284) (← links)
• 6-Thioguanine perturbs cytosine methylation at the CpG dinucleotide site by DNA methyltransferases in vitro and acts as a DNA demethylating agent in vivo (Q37171158) (← links)
• Methotrexate/6-mercaptopurine maintenance therapy influences the risk of a second malignant neoplasm after childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study (Q37234604) (← links)
• 6-thioguanine induces mitochondrial dysfunction and oxidative DNA damage in acute lymphoblastic leukemia cells (Q37389014) (← links)
• Thiopurine methyltransferase activity is related to the risk of relapse of childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study (Q37502607) (← links)
• Wot the ‘L—Does MutL do? (Q37776339) (← links)
• Multifaceted Roles of Alkyltransferase and Related Proteins in DNA Repair, DNA Damage, Resistance to Chemotherapy, and Research Tools (Q37861732) (← links)
• Mismatch repair deficient human cells: spontaneous and MNNG-induced mutational spectra in the HPRT gene (Q38311693) (← links)
• Ambiguous coding is required for the lethal interaction between methylated DNA bases and DNA mismatch repair (Q38359084) (← links)
• Mechanistic mathematical modelling of mercaptopurine effects on cell cycle of human acute lymphoblastic leukaemia cells (Q40342697) (← links)
• Mutagenic and cytotoxic properties of 6-thioguanine, S6-methylthioguanine, and guanine-S6-sulfonic acid. (Q40450769) (← links)
• Spontaneous and chemically induced point mutations in HPRT cDNA of the metabolically competent human lymphoblastoid cell line, MCL-5. (Q40906212) (← links)
• 6-thioguanine resistance in a human colon carcinoma cell line with unaltered levels of hypoxanthine guanine phosphoribosyltransferase activity (Q40942255) (← links)
• Combined mismatch and nucleotide excision repair defects in a human cell line: mismatch repair processes methylation but not UV- or ionizing radiation-induced DNA damage. (Q40953374) (← links)
• Dose reduction of coadministered 6-mercaptopurine decreases myelotoxicity following high-dose methotrexate in childhood leukemia (Q44497845) (← links)
• MSH6 haploinsufficiency at relapse contributes to the development of thiopurine resistance in pediatric B-lymphoblastic leukemia (Q49959979) (← links)
• Sensitivity to DNA cross-linking chemotherapeutic agents in mismatch repair-defective cells in vitro and in xenografts (Q73504363) (← links)
• Reactive DNA. 2. Thioguanine used as a peg site for direct and specific introduction of biologically useful functional groups (Q77749007) (← links)
• Results of a phase II clinical trial of 6-mercaptopurine (6MP) and methotrexate in patients with BRCA-defective tumours (Q91782745) (← links)