Pages that link to "Q58322007"
Jump to navigation
Jump to search
The following pages link to Kinetic Instability of p53 Core Domain Mutants (Q58322007):
Displaying 50 items.
- Mutant p53 proteins bind DNA in a DNA structure-selective mode (Q24791476) (← links)
- Targeted rescue of a destabilized mutant of p53 by an in silico screened drug (Q27651295) (← links)
- Stabilising the DNA-binding domain of p53 by rational design of its hydrophobic core (Q27655864) (← links)
- Interaction of the p53 DNA-Binding Domain with Its N-Terminal Extension Modulates the Stability of the p53 Tetramer (Q27667399) (← links)
- Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant p53 (Q27678152) (← links)
- Wrapping effects within a proposed function-rescue strategy for the Y220C oncogenic mutation of protein p53 (Q28485288) (← links)
- Hydrogen Bond Dynamic Propensity Studies for Protein Binding and Drug Design (Q28553055) (← links)
- Misfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer. (Q30374671) (← links)
- Meet me halfway: when genomics meets structural bioinformatics (Q30400158) (← links)
- Reversible aggregation plays a crucial role on the folding landscape of p53 core domain (Q30951237) (← links)
- Solution structure of p53 core domain: structural basis for its instability (Q31031898) (← links)
- Genetic selection for protein solubility enabled by the folding quality control feature of the twin-arginine translocation pathway (Q33232877) (← links)
- Prediction by graph theoretic measures of structural effects in proteins arising from non-synonymous single nucleotide polymorphisms (Q33354935) (← links)
- SCH529074, a small molecule activator of mutant p53, which binds p53 DNA binding domain (DBD), restores growth-suppressive function to mutant p53 and interrupts HDM2-mediated ubiquitination of wild type p53 (Q33795918) (← links)
- Altered native stability is the dominant basis for susceptibility of α1-antitrypsin mutants to polymerization (Q33842205) (← links)
- A novel p53 phosphorylation site within the MDM2 ubiquitination signal: II. a model in which phosphorylation at SER269 induces a mutant conformation to p53 (Q34333807) (← links)
- Stability of p53 homologs (Q34462386) (← links)
- A single-molecule characterization of p53 search on DNA (Q34490695) (← links)
- Mechanism of initiation of aggregation of p53 revealed by Φ-value analysis (Q35134797) (← links)
- Cancer therapeutic approach based on conformational stabilization of mutant p53 protein by small peptides. (Q38636185) (← links)
- The tumor suppressor gene TP53: implications for cancer management and therapy (Q35986418) (← links)
- Distinct transcriptional responses elicited by unfolded nuclear or cytoplasmic protein in mammalian cells (Q36049159) (← links)
- Kinetic mechanism of p53 oncogenic mutant aggregation and its inhibition (Q36187316) (← links)
- Evaluating Drosophila p53 as a model system for studying cancer mutations (Q36492803) (← links)
- Exploiting the p53 pathway for the diagnosis and therapy of human cancer. (Q36547790) (← links)
- Restoration of wild-type p53 function in human cancer: relevance for tumor therapy. (Q36710840) (← links)
- Restoration of DNA-binding and growth-suppressive activity of mutant forms of p53 via a PCAF-mediated acetylation pathway (Q36733743) (← links)
- Structure-function-rescue: the diverse nature of common p53 cancer mutants (Q36777367) (← links)
- Reactivation of mutant p53: molecular mechanisms and therapeutic potential (Q36777373) (← links)
- Structural biology of the tumor suppressor p53 and cancer-associated mutants (Q36786022) (← links)
- Unfolding, aggregation, and amyloid formation by the tetramerization domain from mutant p53 associated with lung cancer (Q36876885) (← links)
- Rescue of mutants of the tumor suppressor p53 in cancer cells by a designed peptide (Q37088668) (← links)
- Ultraslow oligomerization equilibria of p53 and its implications (Q37318326) (← links)
- Structural and functional constraints in the evolution of protein families (Q37597886) (← links)
- The tumor suppressor p53: from structures to drug discovery (Q37762069) (← links)
- From peptides to proteins: lessons from my years at the Centre for Protein Engineering (Q37808312) (← links)
- The missing Zinc: p53 misfolding and cancer (Q37808944) (← links)
- Expanding the prion concept to cancer biology: dominant-negative effect of aggregates of mutant p53 tumour suppressor (Q38134099) (← links)
- Aggregation and Prion-Like Properties of Misfolded Tumor Suppressors: Is Cancer a Prion Disease? (Q38934098) (← links)
- Reviving the guardian of the genome: Small molecule activators of p53. (Q39205536) (← links)
- Effects of stability on the biological function of p53. (Q39809467) (← links)
- The transcription-independent mitochondrial p53 program is a major contributor to nutlin-induced apoptosis in tumor cells (Q39857411) (← links)
- Molecular spectrum of TP53 mutations in plasma cell dyscrasias by next generation sequencing: an Italian cohort study and overview of the literature (Q40002181) (← links)
- Stabilization of mutant p53 via alkylation of cysteines and effects on DNA binding (Q41453979) (← links)
- Folding of a cyclin box: linking multitarget binding to marginal stability, oligomerization, and aggregation of the retinoblastoma tumor suppressor AB pocket domain (Q41468886) (← links)
- A novel function for p53: regulation of growth cone motility through interaction with Rho kinase (Q41484212) (← links)
- Multisite aggregation of p53 and implications for drug rescue (Q41677793) (← links)
- Vermont: a multi-perspective visual interactive platform for mutational analysis (Q41695683) (← links)
- Single-Molecule characterization of oligomerization kinetics and equilibria of the tumor suppressor p53 (Q41768808) (← links)
- The Genomics of Lung Adenocarcinoma: Opportunities for Targeted Therapies (Q41891513) (← links)