Pages that link to "Q52003845"

The following pages link to Conditional deletion of Shp2 tyrosine phosphatase in thymocytes suppresses both pre-TCR and TCR signals (Q52003845):

Displaying 40 items.

• A THEMIS:SHP1 complex promotes T-cell survival (Q24310969) (← links)
• The PD1:PD-L1/2 Pathway from Discovery to Clinical Implementation (Q28066941) (← links)
• The protein tyrosine phosphatase PTPN4/PTP-MEG1, an enzyme capable of dephosphorylating the TCR ITAMs and regulating NF-kappaB, is dispensable for T cell development and/or T cell effector functions (Q28507911) (← links)
• SHP-1 and SHP-2 in T cells: two phosphatases functioning at many levels (Q30436912) (← links)
• Quantitative analysis of intracellular communication and signaling errors in signaling networks (Q30605125) (← links)
• A Src family kinase-Shp2 axis controls RUNX1 activity in megakaryocyte and T-lymphocyte differentiation (Q32884462) (← links)
• Prolactin receptor-integrin cross-talk mediated by SIRPα in breast cancer cells (Q34279935) (← links)
• SHP2 is a target of the immunosuppressant tautomycetin (Q34554631) (← links)
• Development of severe skeletal defects in induced SHP-2-deficient adult mice: a model of skeletal malformation in humans with SHP-2 mutations (Q34611774) (← links)
• Deletion of Snai2 and Snai3 results in impaired physical development compounded by lymphocyte deficiency (Q34853424) (← links)
• A quantitative assessment of costimulation and phosphatase activity on microclusters in early T cell signaling. (Q35036951) (← links)
• Protein Tyrosine Phosphatase SHP-2 (PTPN11) in Hematopoiesis and Leukemogenesis (Q35101627) (← links)
• Leukocyte-associated Ig-like receptor-1-deficient mice have an altered immune cell phenotype (Q35776073) (← links)
• T cell activation is reduced by the catalytically inactive form of protein tyrosine phosphatase SHP-2 (Q35791560) (← links)
• Deletion of the tyrosine phosphatase Shp2 in Sertoli cells causes infertility in mice (Q38632294) (← links)
• Protein Tyrosine Phosphatase SHP-1 Modulates T Cell Responses by Controlling Cbl-b Degradation (Q36177042) (← links)
• Shp2 plays an important role in acute cigarette smoke-mediated lung inflammation (Q36393427) (← links)
• Inhibition of SHP2 ameliorates the pathogenesis of systemic lupus erythematosus. (Q36951816) (← links)
• Abnormal PTPN11 enhancer methylation promotes rheumatoid arthritis fibroblast-like synoviocyte aggressiveness and joint inflammation (Q36956438) (← links)
• Loss of SHP-2 activity in CD4 T cells promotes melanoma progression and metastasis (Q37211936) (← links)
• Blocking initial infiltration of pioneer CD8( ) T-cells into the CNS via inhibition of SHP-2 ameliorates experimental autoimmune encephalomyelitis in mice (Q37665608) (← links)
• A VISTA on PD-1H. (Q37726700) (← links)
• The tyrosine phosphatase Shp2 in development and cancer (Q37732956) (← links)
• Regulation of TCR signalling by tyrosine phosphatases: from immune homeostasis to autoimmunity (Q38031978) (← links)
• Targeting protein tyrosine phosphatase SHP2 for therapeutic intervention (Q38261370) (← links)
• THEMIS: Two Models, Different Thresholds (Q38683647) (← links)
• Modeling RASopathies with Genetically Modified Mouse Models. (Q39031139) (← links)
• Src homology 2-containing protein tyrosine phosphatase-2 acts as a negative regulator for MUC5AC transcription via the inhibition of the ERK1/2 MAPK signalling pathway in the airway (Q39167357) (← links)
• An adenoviral vector encoding dominant negative Cbl lowers the threshold for T cell activation in post-thymic T cells (Q41547133) (← links)
• Conditional deletion of PTEN in peripheral T cells augments TCR-mediated activation but does not abrogate CD28 dependency or prevent anergy induction (Q42194172) (← links)
• Ptpn11 Deletion in CD4 Cells Does Not Affect T Cell Development and Functions but Causes Cartilage Tumors in a T Cell-Independent Manner (Q45285840) (← links)
• Fine-Tuning of Optimal TCR Signaling in Tumor-Redirected CD8 T Cells by Distinct TCR Affinity-Mediated Mechanisms. (Q47113506) (← links)
• A reappraisal of CTLA-4 checkpoint blockade in cancer immunotherapy. (Q52689094) (← links)
• Protein Tyrosine Phosphatases: Regulators of CD4 T Cells in Inflammatory Bowel Disease (Q59133604) (← links)
• Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells (Q62658228) (← links)
• PD-1 signaling affects cristae morphology and leads to mitochondrial dysfunction in human CD8 T lymphocytes. (Q64915332) (← links)
• Interaction of SHP-2 SH2 domains with PD-1 ITSM induces PD-1 dimerization and SHP-2 activation (Q90408578) (← links)
• Regulation of CD4 T Cell Signaling and Immunological Synapse by Protein Tyrosine Phosphatases: Molecular Mechanisms in Autoimmunity (Q91811501) (← links)
• Revisiting the PD-1 pathway (Q99571808) (← links)
• The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies (Q99637295) (← links)