Pages that link to "Q46819658"

The following pages link to The novel class III antiarrhythmics NE-10064 and NE-10133 inhibit IsK channels expressed in Xenopus oocytes and IKs in guinea pig cardiac myocytes (Q46819658):

Displaying 40 items.

• Effects of azimilide, a KV(r) and KV(s) blocker, on canine ventricular arrhythmia models (Q28370507) (← links)
• The role of the IsK protein in the specific pharmacological properties of the IKs channel complex (Q28379136) (← links)
• Regulation of voltage-gated K channel expression in the developing mammalian myocardium (Q31997375) (← links)
• Cardiovascular parameters in anaesthetized guinea pigs: a safety pharmacology screening model (Q33217289) (← links)
• Inner ear defects induced by null mutation of the isk gene (Q34412325) (← links)
• A review of class III antiarrhythmic agents for atrial fibrillation: maintenance of normal sinus rhythm (Q34476908) (← links)
• Blockade of HERG channels by the class III antiarrhythmic azimilide: mode of action (Q35027053) (← links)
• Cardiac ventricular repolarization reserve: a principle for understanding drug-related proarrhythmic risk. (Q35210010) (← links)
• Pharmacological properties and functional role of Kslow current in mouse pancreatic beta-cells: SK channels contribute to Kslow tail current and modulate insulin secretion (Q36493671) (← links)
• Anti-minK Antisense Decreases the Amplitude of the Rapidly Activating Cardiac Delayed Rectifier K Current (Q36684678) (← links)
• Predicting QT prolongation in humans during early drug development using hERG inhibition and an anaesthetized guinea-pig model (Q36742821) (← links)
• Supplemental studies for cardiovascular risk assessment in safety pharmacology: a critical overview (Q37909132) (← links)
• Role of the ISK protein in the IminK channel complex (Q41441268) (← links)
• Antiarrhythmic agents: Current status and perspectives (Q41581039) (← links)
• Recent advances in potassium channel modulation (Q41655342) (← links)
• Azimilide dihydrochloride, a novel antiarrhythmic agent (Q41736474) (← links)
• The inhibitory effect of the antipsychotic drug haloperidol on HERG potassium channels expressed in Xenopus oocytes (Q41849017) (← links)
• The azimilide post-infarct survival evaluation (ALIVE) trial (Q42543714) (← links)
• Interaction of azimilide with neurohumoral and channel receptors. (Q42825825) (← links)
• Apparent desensitization of the effects of sigma receptor ligand haloperidol in isolated rat and guinea pig hearts after chronic treatment (Q43211133) (← links)
• The anesthetized guinea pig: an effective early cardiovascular derisking and lead optimization model (Q44031835) (← links)
• Sensitivity and specificity of isolated perfused guinea pig heart to test for drug-induced lengthening of QTc. (Q44689852) (← links)
• QT interval correction assessment in the anesthetized guinea pig. (Q46725144) (← links)
• Comparison of the rate-dependent properties of the class III antiarrhythmic agents azimilide (NE-10064) and E-4031: considerations on the mechanism of reverse rate-dependent action potential prolongation (Q46768546) (← links)
• Inhibition of minK protein induced K channels in Xenopus oocytes by estrogens (Q48970946) (← links)
• Specific blockade of slowly activating I(sK) channels by chromanols -- impact on the role of I(sK) channels in epithelia (Q48972643) (← links)
• Inhibition of IKs in guinea pig cardiac myocytes and guinea pig IsK channels by the chromanol 293B. (Q48985465) (← links)
• Effect of isosorbiddinitrate on exogenously expressed slowly activating K channels and endogenous K channels in Xenopus oocytes (Q49016685) (← links)
• Molecular basis of IsK protein regulation by oxidation or chelation (Q49064938) (← links)
• cAMP stimulation of CFTR-expressing Xenopus oocytes activates a chromanol-inhibitable K conductance (Q50761581) (← links)
• Effect of Age and Gender on Azimilide Pharmacokinetics After a Single Oral Dose of Azimilide Dihydrochloride (Q50902148) (← links)
• Azimilide decreases defibrillation voltage requirements and increases spatial organization during ventricular fibrillation. (Q52213143) (← links)
• Antiarrhythmic drugs and cardiac ion channels: mechanisms of action. (Q53943964) (← links)
• The cAMP-regulated and 293B-inhibited K conductance of rat colonic crypt base cells (Q71142165) (← links)
• Pharmacokinetics and pharmacodynamics following intravenous doses of azimilide dihydrochloride (Q73245584) (← links)
• Azimilide (Q73578520) (← links)
• Azimilide pharmacokinetics and pharmacodynamics upon multiple oral dosing (Q77333887) (← links)
• Separation and quantitation of azimilide and its putative metabolites by capillary electrophoresis (Q77804348) (← links)
• Monophasic action potential in anaesthetized guinea pigs as a biomarker for prediction of liability for drug-induced delayed ventricular repolarization (Q79577889) (← links)
• Animal models of arrhythmia: classic electrophysiology to genetically modified large animals (Q92512512) (← links)