Pages that link to "Q40949921"
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The following pages link to Sigmoidal kinetic model for two co-operative substrate-binding sites in a cytochrome P450 3A4 active site: an example of the metabolism of diazepam and its derivatives (Q40949921):
Displaying 24 items.
- Intrinsic noise analyzer: a software package for the exploration of stochastic biochemical kinetics using the system size expansion (Q21134535) (← links)
- A novel type of allosteric regulation: functional cooperativity in monomeric proteins (Q27011182) (← links)
- A kinetic model for the metabolic interaction of two substrates at the active site of cytochrome P450 3A4. (Q31510190) (← links)
- Determination of metabolic profile of anti‐malarial trioxane CDRI 99/411 in rat liver microsomes using HPLC (Q33876677) (← links)
- Allosteric phenomena in cytochrome P450-catalyzed monooxygenations (Q34370833) (← links)
- Participation of CYP2C8 and CYP3A4 in the N‐demethylation of imatinib in human hepatic microsomes (Q34389029) (← links)
- CYP2C9 genotype-dependent effects on in vitro drug-drug interactions: switching of benzbromarone effect from inhibition to activation in the CYP2C9.3 variant. (Q34426453) (← links)
- Human drug metabolism and the cytochromes P450: application and relevance of in vitro models (Q34430456) (← links)
- Role of P-glycoprotein in pharmacokinetics: clinical implications (Q35029495) (← links)
- Effective experimental design: enzyme kinetics in the bioinformatics era. (Q35053169) (← links)
- A Screen of Approved Drugs Identifies the Androgen Receptor Antagonist Flutamide and Its Pharmacologically Active Metabolite 2-Hydroxy-Flutamide as Heterotropic Activators of Cytochrome P450 3A In Vitro and In Vivo (Q35743429) (← links)
- Energetics of heterotropic cooperativity between alpha-naphthoflavone and testosterone binding to CYP3A4 (Q36113874) (← links)
- QM/MM study of the active species of the human cytochrome P450 3A4, and the influence thereof of the multiple substrate binding (Q37000689) (← links)
- Modeling kinetics of subcellular disposition of chemicals. (Q37194304) (← links)
- Heterotropic activation of the midazolam hydroxylase activity of CYP3A by a positive allosteric modulator of mGlu5: in vitro to in vivo translation and potential impact on clinically relevant drug-drug interactions (Q37325581) (← links)
- Cooperative properties of cytochromes P450. (Q37366156) (← links)
- In vitro oxidative decarboxylation of free fatty acids to terminal alkenes by two new P450 peroxygenases (Q41590516) (← links)
- Optimized on-line enantioselective capillary electrophoretic method for kinetic and inhibition studies of drug metabolism mediated by cytochrome P450 enzymes (Q41670293) (← links)
- Kinetic analysis for multiple substrate interaction at the active site of cytochrome P450. (Q44211547) (← links)
- Efficient and accurate experimental design for enzyme kinetics: Bayesian studies reveal a systematic approach. (Q44356970) (← links)
- Induction of CYP3A by ethanol in multiple in vitro and in vivo models (Q44490210) (← links)
- Anomalous fluctuation scaling laws in stochastic enzyme kinetics: increase of noise strength with the mean concentration (Q46926093) (← links)
- Evaluation of modafinil as a perpetrator of metabolic drug-drug interactions using a model informed cocktail reaction phenotyping trial protocol (Q47409686) (← links)
- Steroid bioconjugation to a CYP3A4 allosteric site and its effect on substrate binding and coupling efficiency (Q89353053) (← links)