Pages that link to "Q40290604"

The following pages link to OSU-03012 promotes caspase-independent but PERK-, cathepsin B-, BID-, and AIF-dependent killing of transformed cells (Q40290604):

Displaying 44 items.

• Metallic nickel nano- and fine particles induce JB6 cell apoptosis through a caspase-8/AIF mediated cytochrome c-independent pathway (Q23914979) (← links)
• GRP78/BiP/HSPA5/Dna K is a universal therapeutic target for human disease (Q28254667) (← links)
• Modulation of the Akt pathway reveals a novel link with PERK/eIF2α, which is relevant during hypoxia (Q28534963) (← links)
• Growth inhibitory and anti-tumour activities of OSU-03012, a novel PDK-1 inhibitor, on vestibular schwannoma and malignant schwannoma cells (Q30481231) (← links)
• Molecular mechanisms of acquired resistance to tyrosine kinase targeted therapy (Q33828409) (← links)
• Eradication of intracellular Francisella tularensis in THP-1 human macrophages with a novel autophagy inducing agent (Q34087529) (← links)
• Regulation of OSU-03012 toxicity by ER stress proteins and ER stress-inducing drugs (Q34289307) (← links)
• OSU-03012 interacts with lapatinib to kill brain cancer cells (Q34300517) (← links)
• Moderately elevated intracranial pressure after diffuse traumatic brain injury is associated with exacerbated neuronal pathology and behavioral morbidity in the rat. (Q34727074) (← links)
• OSU-03012 sensitizes breast cancers to lapatinib-induced cell killing: a role for Nck1 but not Nck2. (Q34739677) (← links)
• Celecoxib analogs that lack COX-2 inhibitory function: preclinical development of novel anticancer drugs (Q34743086) (← links)
• Eradication of intracellular Salmonella enterica serovar Typhimurium with a small-molecule, host cell-directed agent (Q35006658) (← links)
• Sphingosine-1-phosphate phosphohydrolase-1 regulates ER stress-induced autophagy (Q35092604) (← links)
• HSPA5/Dna K may be a useful target for human disease therapies (Q35110761) (← links)
• Sorafenib Enhances Pemetrexed Cytotoxicity through an Autophagy-Dependent Mechanism in Cancer Cells (Q35113327) (← links)
• PDE5 inhibitors enhance celecoxib killing in multiple tumor types (Q35430943) (← links)
• Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health (Q35679353) (← links)
• Regulation of dimethyl-fumarate toxicity by proteasome inhibitors (Q36215658) (← links)
• OSU-03012 and Viagra Treatment Inhibits the Activity of Multiple Chaperone Proteins and Disrupts the Blood-Brain Barrier: Implications for Anti-Cancer Therapies (Q36808317) (← links)
• GRP78/Dna K Is a Target for Nexavar/Stivarga/Votrient in the Treatment of Human Malignancies, Viral Infections and Bacterial Diseases (Q36830763) (← links)
• Lysosomal cysteine cathepsins: signaling pathways in apoptosis (Q36841861) (← links)
• Sensitivity to the non-COX inhibiting celecoxib derivative, OSU03012, is p21(WAF1/CIP1) dependent (Q37019382) (← links)
• Multi-kinase inhibitors can associate with heat shock proteins through their NH2-termini by which they suppress chaperone function (Q37022352) (← links)
• OSU-03012 stimulates PKR-like endoplasmic reticulum-dependent increases in 70-kDa heat shock protein expression, attenuating its lethal actions in transformed cells (Q37172898) (← links)
• Endoplasmic reticulum stress: its role in disease and novel prospects for therapy (Q37288073) (← links)
• Multi-kinase inhibitors interact with sildenafil and ERBB1/2/4 inhibitors to kill tumor cells in vitro and in vivo (Q37457895) (← links)
• Targeting endoplasmic reticulum stress and Akt with OSU-03012 and gefitinib or erlotinib to overcome resistance to epidermal growth factor receptor inhibitors. (Q37523188) (← links)
• Ethanol induces cell cycle arrest and triggers apoptosis via Sp1-dependent p75NTR expression in human neuroblastoma cells. (Q38446997) (← links)
• AR-12 Inhibits Multiple Chaperones Concomitant With Stimulating Autophagosome Formation Collectively Preventing Virus Replication. (Q38770459) (← links)
• Aurora kinase A is a possible target of OSU‑03012 to destabilize MYC family proteins (Q38975838) (← links)
• Antitumor mechanisms of targeting the PDK1 pathway in head and neck cancer (Q39366540) (← links)
• OSU-03012 suppresses GRP78/BiP expression that causes PERK-dependent increases in tumor cell killing (Q39392716) (← links)
• Effects of small molecule inhibitors of PI3K/Akt/mTOR signaling on neuroblastoma growth in vitro and in vivo (Q39515479) (← links)
• OSU-03012 enhances Ad.7-induced GBM cell killing via ER stress and autophagy and by decreasing expression of mitochondrial protective proteins (Q39747108) (← links)
• AR-12 Inhibits Chaperone Proteins Preventing Virus Replication and the Accumulation of Toxic Misfolded Proteins (Q40412357) (← links)
• Increased intracranial pressure after diffuse traumatic brain injury exacerbates neuronal somatic membrane poration but not axonal injury: evidence for primary intracranial pressure-induced neuronal perturbation (Q42157107) (← links)
• OSU-03012, a novel celecoxib derivative, induces cell swelling and shortens action potential duration in mouse ventricular cells (Q42771474) (← links)
• Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis (Q42792442) (← links)
• Exploring the molecular mechanisms of OSU-03012 on vascular smooth muscle cell proliferation (Q42972124) (← links)
• Sensitizing estrogen receptor-negative breast cancer cells to tamoxifen with OSU-03012, a novel celecoxib-derived phosphoinositide-dependent protein kinase-1/Akt signaling inhibitor (Q46643620) (← links)
• The irreversible ERBB1/2/4 inhibitor neratinib interacts with the BCL-2 inhibitor venetoclax to kill mammary cancer cells. (Q50047476) (← links)
• Epibrassinolide alters PI3K/MAPK signaling axis via activating Foxo3a-induced mitochondria-mediated apoptosis in colon cancer cells. (Q53368213) (← links)
• Combining autophagy stimulators and cellulose ethers for therapy against prion disease (Q71377429) (← links)
• Valproate augments Niraparib killing of tumor cells (Q89164375) (← links)