Pages that link to "Q39045188"

The following pages link to Discovery of a novel class of dimeric Smac mimetics as potent IAP antagonists resulting in a clinical candidate for the treatment of cancer (AZD5582). (Q39045188):

Displaying 19 items.

• Caspase-8 activation by TRAIL monotherapy predicts responses to IAPi and TRAIL combination treatment in breast cancer cell lines (Q30398758) (← links)
• Inducing death in tumor cells: roles of the inhibitor of apoptosis proteins. (Q33632016) (← links)
• A novel small-molecule IAP antagonist, AZD5582, draws Mcl-1 down-regulation for induction of apoptosis through targeting of cIAP1 and XIAP in human pancreatic cancer (Q36413644) (← links)
• Targeting the inhibitor of Apoptosis Protein BIR3 binding domains (Q38226672) (← links)
• Small molecule inhibitor of apoptosis proteins antagonists: a patent review (Q38484840) (← links)
• Pharmacology of smac mimetics; chemotype differentiation based on physical association with caspase regulators and cellular transport (Q38841307) (← links)
• Targeting Programmed Cell Death Using Small-Molecule Compounds to Improve Potential Cancer Therapy (Q38881119) (← links)
• Dimeric Macrocyclic Antagonists of Inhibitor of Apoptosis Proteins for the Treatment of Cancer (Q41108779) (← links)
• Mitochondrial oligomers boost glycolysis in cancer stem cells to facilitate blebbishield-mediated transformation after apoptosis (Q41767236) (← links)
• Selective IAP inhibition results in sensitization of unstimulated but not CD40-stimulated chronic lymphocytic leukaemia cells to TRAIL-induced apoptosis (Q42930877) (← links)
• Interferon-γ and Smac mimetics synergize to induce apoptosis of lung cancer cells in a TNFα-independent manner. (Q55339903) (← links)
• Notch Signaling Regulates Mitochondrial Metabolism and NF-κB Activity in Triple-Negative Breast Cancer Cells via IKKα-Dependent Non-canonical Pathways (Q60046964) (← links)
• Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12 (Q64112827) (← links)
• Anti-apoptotic proteins in the autophagic world: an update on functions of XIAP, Survivin, and BRUCE (Q89530700) (← links)
• Targeting apoptotic caspases in cancer (Q89840958) (← links)
• Conformational characterization of full-length X-chromosome-linked inhibitor of apoptosis protein (XIAP) through an integrated approach (Q90428040) (← links)
• Bivalent SMAC Mimetics for Treating Cancer by Antagonizing Inhibitor of Apoptosis Proteins (Q91137985) (← links)
• Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo (Q92860944) (← links)
• Pharmacological Activation of Non-canonical NF-κB Signaling Activates Latent HIV-1 Reservoirs In Vivo (Q102144611) (← links)