Pages that link to "Q38924086"

The following pages link to Tricyclic covalent inhibitors selectively target Jak3 through an active site thiol. (Q38924086):

Displaying 23 items.

• JAK kinase targeting in hematologic malignancies: a sinuous pathway from identification of genetic alterations towards clinical indications (Q26782539) (← links)
• Essential biphasic role for JAK3 catalytic activity in IL-2 receptor signaling (Q28834529) (← links)
• Targeting Non-Catalytic Cysteine Residues Through Structure-Guided Drug Discovery (Q30390894) (← links)
• Pseudokinases: update on their functions and evaluation as new drug targets (Q30397636) (← links)
• SAR Studies of 5-Aminopyrazole-4-carboxamide Analogues as Potent and Selective Inhibitors of Toxoplasma gondii CDPK1. (Q36368024) (← links)
• Progress toward JAK1-selective inhibitors (Q38357083) (← links)
• Development of Selective Covalent Janus Kinase 3 Inhibitors. (Q38763094) (← links)
• Rethinking JAK2 inhibition: towards novel strategies of more specific and versatile janus kinase inhibition (Q39101779) (← links)
• Advances in bumped kinase inhibitors for human and animal therapy for cryptosporidiosis. (Q40050616) (← links)
• Selective JAK3 Inhibitors with a Covalent Reversible Binding Mode Targeting a New Induced Fit Binding Pocket (Q41835379) (← links)
• JAK inhibition as a therapeutic strategy for immune and inflammatory diseases (Q47439880) (← links)
• Design and Synthesis of a Highly Selective JAK3 Inhibitor for the Treatment of Rheumatoid Arthritis (Q48297847) (← links)
• JAK inhibition as a therapeutic strategy for immune and inflammatory diseases. (Q48556502) (← links)
• Oncogenic activation of JAK3-STAT signaling confers clinical sensitivity to PRN371, a novel selective and potent JAK3 inhibitor, in natural killer/T-cell lymphoma (Q50055394) (← links)
• Discovery of a highly selective JAK3 inhibitor for the treatment of rheumatoid arthritis. (Q52626728) (← links)
• Hyperactivation of Oncogenic JAK3 Mutants Depend on ATP Binding to the Pseudokinase Domain (Q60047595) (← links)
• Essential Kinases and Transcriptional Regulators and Their Roles in Autoimmunity. (Q64992442) (← links)
• Structure-Activity Relationship between Thiol Group-Trapping Ability of Morphinan Compounds with a Michael Acceptor and Anti-Plasmodium falciparum Activities (Q90048122) (← links)
• Selective and reversible modification of kinase cysteines with chlorofluoroacetamides (Q91048638) (← links)
• Controlling cellular distribution of drugs with permeability modifying moieties (Q91866799) (← links)
• Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis (Q92490680) (← links)
• Systematic Studies on the Protocol and Criteria for Selecting a Covalent Docking Tool (Q92662272) (← links)
• Design of novel JAK3 Inhibitors towards Rheumatoid Arthritis using molecular docking analysis (Q92758944) (← links)