Pages that link to "Q37183495"
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The following pages link to The Antifolates (Q37183495):
Displaying 50 items.
- Biology of the major facilitative folate transporters SLC19A1 and SLC46A1 (Q26998717) (← links)
- Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition (Q27679502) (← links)
- Methotrexate Is a JAK/STAT Pathway Inhibitor (Q28546079) (← links)
- Ceramide Synthase 6 Is a Novel Target of Methotrexate Mediating Its Antiproliferative Effect in a p53-Dependent Manner (Q28552611) (← links)
- A hybrid stochastic model of folate-mediated one-carbon metabolism: Effect of the common C677T MTHFR variant on de novo thymidylate biosynthesis (Q33678139) (← links)
- Hydroxyethyl starch as an effective methotrexate carrier in anticancer therapy (Q34292505) (← links)
- Structure-activity profiles of novel 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolates with modified amino acids for cellular uptake by folate receptors α and β and the proton-coupled folate transporter (Q34313771) (← links)
- Novel 5-substituted pyrrolo[2,3-d]pyrimidines as dual inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase and as potential antitumor agents. (Q36467569) (← links)
- Glucose conjugation for the specific targeting and treatment of cancer (Q37200539) (← links)
- The membrane transport and polyglutamation of pralatrexate: a new-generation dihydrofolate reductase inhibitor (Q37200566) (← links)
- Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosy (Q37246257) (← links)
- Glucarpidase (voraxaze), a carboxypeptidase enzyme for methotrexate toxicity (Q37419418) (← links)
- Tumor-targeting with novel non-benzoyl 6-substituted straight chain pyrrolo[2,3-d]pyrimidine antifolates via cellular uptake by folate receptor α and inhibition of de novo purine nucleotide biosynthesis (Q37432606) (← links)
- Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase (Q37587969) (← links)
- The major facilitative folate transporters solute carrier 19A1 and solute carrier 46A1: biology and role in antifolate chemotherapy of cancer (Q37663377) (← links)
- Methotrexate diethyl ester-loaded lipid-core nanocapsules in aqueous solution increased antineoplastic effects in resistant breast cancer cell line. (Q37676084) (← links)
- Clinical presentation and protocol for management of hepatic sarcoidosis (Q38282948) (← links)
- Apoptosis and associated phenomena as a determinants of the efficacy of photodynamic therapy (Q38307797) (← links)
- Antivitamins for Medicinal Applications (Q38503308) (← links)
- Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype (Q38720227) (← links)
- Cancer metabolism: a therapeutic perspective (Q38824435) (← links)
- Chemotherapy and Transplantation: The Role of Immunosuppression in Malignancy and a Review of Antineoplastic Agents in Solid Organ Transplant Recipients (Q38844500) (← links)
- Mechanism of action of methotrexate in rheumatoid arthritis, and the search for biomarkers. (Q38991972) (← links)
- Hydrophobic ion pairing as a strategy to improve drug encapsulation into lipid nanocarriers for the cancer treatment. (Q39021928) (← links)
- Cancer Metabolism: Fueling More than Just Growth (Q39061395) (← links)
- Alterations in the expression pattern of MTHFR, DHFR, TYMS, and SLC19A1 genes after treatment of laryngeal cancer cells with high and low doses of methotrexate. (Q39128356) (← links)
- Methotrexate toxicity treated with continuous venovenous hemofiltration, leucovorin and glucarpidase (Q39368423) (← links)
- The impact of 5-formyltetrahydrofolate on the anti-tumor activity of pralatrexate, as compared to methotrexate, in HeLa cells in vitro (Q39535518) (← links)
- Type 3 innate lymphoid cells maintain intestinal epithelial stem cells after tissue damage (Q40516809) (← links)
- Arsenic trioxide targets MTHFD1 and SUMO-dependent nuclear de novo thymidylate biosynthesis. (Q41710207) (← links)
- Coupling to a cancer-selective heparan-sulfate-targeted branched peptide can by-pass breast cancer cell resistance to methotrexate (Q47128720) (← links)
- The promise and challenges of exploiting the proton-coupled folate transporter for selective therapeutic targeting of cancer (Q50062142) (← links)
- Tumor Targeting with Novel Pyridyl 6-Substituted Pyrrolo[2,3-d]Pyrimidine Antifolates Via Cellular Uptake by Folate Receptor α and the Proton-coupled Folate Transporter and Inhibition of De Novo Purine Nucleotide Biosynthesis. (Q50098317) (← links)
- Development and validation of chemical features-based proton-coupled folate transporter/activity and reduced folate carrier/activity models (pharmacophores). (Q51730395) (← links)
- Fluorine-Substituted Pyrrolo[2,3- d]Pyrimidine Analogues with Tumor Targeting via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis (Q52559376) (← links)
- Metabolic Enzymes in Sarcomagenesis: Progress Toward Biology and Therapy. (Q52757920) (← links)
- Overexpression of dihydrofolate reductase is a factor of poor survival in acute lymphoblastic leukemia. (Q55282837) (← links)
- Non-Hodgkin Lymphoma Metabolism (Q60628572) (← links)
- Combined antitumoral effects of pretubulysin and methotrexate (Q61445534) (← links)
- Rat liver folate metabolism can provide an independent functioning of associated metabolic pathways (Q64273555) (← links)
- Discovery of 5-substituted pyrrolo[2,3-d]pyrimidine antifolates as dual-acting inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis: (Q86808095) (← links)
- Methionine metabolism in health and cancer: a nexus of diet and precision medicine (Q90084125) (← links)
- Multitargeting Compounds: A Promising Strategy to Overcome Multi-Drug Resistant Tuberculosis (Q90396097) (← links)
- Renal Reabsorption of Folates: Pharmacological and Toxicological Snapshots (Q90462052) (← links)
- Coenzyme F420-Dependent Glucose-6-Phosphate Dehydrogenase-Coupled Polyglutamylation of Coenzyme F420 in Mycobacteria (Q91700557) (← links)
- Novel Pyrrolo[3,2-d]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy (Q91753121) (← links)
- Loss of ALDH1L1 folate enzyme confers a selective metabolic advantage for tumor progression (Q91833664) (← links)
- Acid-specific formaldehyde donor is a potential, dual targeting cancer chemotherapeutic/chemo preventive drug for FANC/BRCA-mutant cancer (Q92341124) (← links)
- Analytical methodologies for determination of methotrexate and its metabolites in pharmaceutical, biological and environmental samples (Q92342937) (← links)
- The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma (Q94672632) (← links)