Pages that link to "Q36411149"
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The following pages link to ATR signaling can drive cells into senescence in the absence of DNA breaks (Q36411149):
Displaying 50 items.
- Miz1 and HectH9 regulate the stability of the checkpoint protein, TopBP1 (Q24323957) (← links)
- Targeting ATR and Chk1 kinases for cancer treatment: a new model for new (and old) drugs (Q24610287) (← links)
- Common mechanisms of PIKK regulation (Q24653672) (← links)
- Linking replication stress with heterochromatin formation (Q26778138) (← links)
- Chromatin perturbations during the DNA damage response in higher eukaryotes (Q26782637) (← links)
- Chemical strategies for development of ATR inhibitors (Q28239738) (← links)
- Activation of the ATR kinase by the RPA-binding protein ETAA1 (Q28596569) (← links)
- ETAA1 acts at stalled replication forks to maintain genome integrity (Q28596606) (← links)
- ATR: an essential regulator of genome integrity (Q29547883) (← links)
- A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity (Q29614209) (← links)
- H2AX is required for cell cycle arrest via the p53/p21 pathway (Q30487614) (← links)
- Persistent telomere damage induces bypass of mitosis and tetraploidy (Q30494078) (← links)
- Mitochondrial hyperfusion induced by loss of the fission protein Drp1 causes ATM-dependent G2/M arrest and aneuploidy through DNA replication stress (Q30581882) (← links)
- Retinoblastoma loss modulates DNA damage response favoring tumor progression (Q33382723) (← links)
- Akt/PKB suppresses DNA damage processing and checkpoint activation in late G2. (Q33647680) (← links)
- Functional significance for a heterogenous ribonucleoprotein A18 signature RNA motif in the 3'-untranslated region of ataxia telangiectasia mutated and Rad3-related (ATR) transcript (Q33726508) (← links)
- Tumor suppression by p53: making cells senescent (Q33736728) (← links)
- Characterization of the Cellular and Antitumor Effects of MPI-0479605, a Small-Molecule Inhibitor of the Mitotic Kinase Mps1 (Q34042530) (← links)
- Aging, cellular senescence, and cancer (Q34199776) (← links)
- Akt: A Double-Edged Sword in Cell Proliferation and Genome Stability (Q34223641) (← links)
- Cooperative functions of Chk1 and Chk2 reduce tumour susceptibility in vivo (Q34241074) (← links)
- Retracted: Interferon-β Induces Cellular Senescence in Cutaneous Human Papilloma Virus-Transformed Human Keratinocytes by Affecting p53 Transactivating Activity (Q34277520) (← links)
- Unfolded p53 in the pathogenesis of Alzheimer's disease: is HIPK2 the link? (Q34322386) (← links)
- Absence of p53-dependent apoptosis leads to UV radiation hypersensitivity, enhanced immunosuppression and cellular senescence (Q34583147) (← links)
- RNAi screen of the protein kinome identifies checkpoint kinase 1 (CHK1) as a therapeutic target in neuroblastoma (Q34602599) (← links)
- p53 governs telomere regulation feedback too, via TRF2 (Q34616697) (← links)
- TRPM7 regulates quiescent/proliferative metabolic transitions in lymphocytes (Q34618964) (← links)
- Tethering DNA Damage Checkpoint Mediator Proteins Topoisomerase IIβ-binding Protein 1 (TopBP1) and Claspin to DNA Activates Ataxia-Telangiectasia Mutated and RAD3-related (ATR) Phosphorylation of Checkpoint Kinase 1 (Chk1) (Q35010875) (← links)
- The tumor suppressor PML specifically accumulates at RPA/Rad51-containing DNA damage repair foci but is nonessential for DNA damage-induced fibroblast senescence (Q35116715) (← links)
- Modelling the onset of senescence at the G1/S cell cycle checkpoint (Q35540742) (← links)
- High levels of TopBP1 induce ATR-dependent shut-down of rRNA transcription and nucleolar segregation. (Q35656774) (← links)
- Key role of dual specificity kinase TTK in proliferation and survival of pancreatic cancer cells. (Q35678047) (← links)
- Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgen-independent prostate cancer cells via regulation of Skp2, p53, p21Cip1 and p27Kip1. (Q35740051) (← links)
- Molecular damage in cancer: an argument for mTOR-driven aging (Q35740772) (← links)
- TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity (Q35904627) (← links)
- Polygenic Effects of Common Single-Nucleotide Polymorphisms on Life Span: When Association Meets Causality (Q36166448) (← links)
- Inhibition of Chk1 with the small molecule inhibitor V158411 induces DNA damage and cell death in an unperturbed S-phase (Q36187661) (← links)
- S-phase-dependent p50/NF-кB1 phosphorylation in response to ATR and replication stress acts to maintain genomic stability (Q36188764) (← links)
- The emerging role of nuclear architecture in DNA repair and genome maintenance (Q36340722) (← links)
- The ATR barrier to replication-born DNA damage. (Q36664049) (← links)
- An autonomous chromatin/DNA-PK mechanism for localized DNA damage signaling in mammalian cells (Q36684796) (← links)
- The orally active and bioavailable ATR kinase inhibitor AZD6738 potentiates the anti-tumor effects of cisplatin to resolve ATM-deficient non-small cell lung cancer in vivo (Q36688959) (← links)
- A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations. (Q36908567) (← links)
- INK4a/ARF limits the expansion of cells suffering from replication stress (Q37017649) (← links)
- The solute carrier SLC35F2 enables YM155-mediated DNA damage toxicity (Q37021087) (← links)
- Living on a break: cellular senescence as a DNA-damage response (Q37198572) (← links)
- p38 Mitogen-activated protein kinase- and HuR-dependent stabilization of p21(Cip1) mRNA mediates the G(1)/S checkpoint (Q37302277) (← links)
- Cdc6 contributes to cisplatin-resistance by activation of ATR-Chk1 pathway in bladder cancer cells (Q37457876) (← links)
- Facilitating replication under stress: an oncogenic function of MYC? (Q37492244) (← links)
- Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer. (Q37569714) (← links)