Pages that link to "Q34977895"

The following pages link to Proinsulin and the genetics of diabetes mellitus (Q34977895):

Displaying 39 items.

• The unfolded protein response: integrating stress signals through the stress sensor IRE1α (Q24293771) (← links)
• INS-gene mutations: from genetics and beta cell biology to clinical disease (Q27013618) (← links)
• Crystal Structure of a"Nonfoldable"Insulin: IMPAIRED FOLDING EFFICIENCY DESPITE NATIVE ACTIVITY (Q27657915) (← links)
• Solution Structure of Proinsulin: CONNECTING DOMAIN FLEXIBILITY AND PROHORMONE PROCESSING (Q27659233) (← links)
• Stimulation of autophagy improves endoplasmic reticulum stress-induced diabetes (Q28506554) (← links)
• Conformational dynamics of insulin (Q30417406) (← links)
• Clinical utility of insulin and insulin analogs (Q30429358) (← links)
• Contribution of residue B5 to the folding and function of insulin and IGF-I: constraints and fine-tuning in the evolution of a protein family. (Q33717728) (← links)
• Mutant INS-gene induced diabetes of youth: proinsulin cysteine residues impose dominant-negative inhibition on wild-type proinsulin transport (Q33719171) (← links)
• Deciphering the hidden informational content of protein sequences: foldability of proinsulin hinges on a flexible arm that is dispensable in the mature hormone (Q34155456) (← links)
• Proinsulin atypical maturation and disposal induces extensive defects in mouse Ins2 /Akita β-cells (Q34235559) (← links)
• Proinsulin misfolding and diabetes: mutant INS gene-induced diabetes of youth (Q34258755) (← links)
• Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion (Q35008217) (← links)
• The Stability of Myocilin Olfactomedin Domain Variants Provides New Insight into Glaucoma as a Protein Misfolding Disorder (Q35083487) (← links)
• Proinsulin misfolding and endoplasmic reticulum stress during the development and progression of diabetes (Q35498877) (← links)
• Structural Analysis of Proinsulin Hexamer Assembly by Hydroxyl Radical Footprinting and Computational Modeling (Q35626221) (← links)
• Action of Protein Disulfide Isomerase on Proinsulin Exit from Endoplasmic Reticulum of Pancreatic β-Cells (Q35643714) (← links)
• Endoplasmic reticulum stress and insulin biosynthesis: a review (Q35829685) (← links)
• COPII-Dependent ER Export: A Critical Component of Insulin Biogenesis and β-Cell ER Homeostasis (Q35897574) (← links)
• Diabetes mellitus due to the toxic misfolding of proinsulin variants (Q37014491) (← links)
• Endoplasmic reticulum oxidoreductin-1α (Ero1α) improves folding and secretion of mutant proinsulin and limits mutant proinsulin-induced endoplasmic reticulum stress. (Q37312157) (← links)
• Aberrant islet unfolded protein response in type 2 diabetes (Q37576214) (← links)
• Calcium efflux from the endoplasmic reticulum leads to β-cell death (Q37863059) (← links)
• Endoplasmic Reticulum Stress and Inflammation in Obesity and Diabetes (Q37784942) (← links)
• Histone deacetylase (HDAC) inhibition as a novel treatment for diabetes mellitus (Q37832964) (← links)
• Insulin gene mutations and diabetes (Q38213044) (← links)
• Theoretical and computational studies of peptides and receptors of the insulin family (Q38354696) (← links)
• New Insights into the Physiological Role of Endoplasmic Reticulum-Associated Degradation (Q39107838) (← links)
• Nisin‐inducible secretion of a biologically active single‐chain insulin analog by Lactococcus lactis NZ9500 (Q39578319) (← links)
• p24 family type 1 transmembrane proteins are required for insulin biosynthesis and secretion in pancreatic beta-cells (Q39720890) (← links)
• Mutant proinsulin proteins associated with neonatal diabetes are retained in the endoplasmic reticulum and not efficiently secreted (Q39759180) (← links)
• Computational study of the activity, dynamics, energetics and conformations of insulin analogues using molecular dynamics simulations: Application to hyperinsulinemia and the critical residue B26. (Q41682209) (← links)
• Evaluation of conformational changes in diabetes-associated mutation in insulin a chain: a molecular dynamics study (Q42559661) (← links)
• Unfolding the mechanisms of disease progression in permanent neonatal diabetes (Q43201821) (← links)
• Identification of INS and KCNJ11 gene mutations in type 1B diabetes in Japanese children with onset of diabetes before 5 years of age. (Q45999247) (← links)
• Misfolded proinsulin in the endoplasmic reticulum during development of beta cell failure in diabetes. (Q48152192) (← links)
• The protein kinase PERK/EIF2AK3 regulates proinsulin processing not via protein synthesis but by controlling endoplasmic reticulum chaperones. (Q52695056) (← links)
• IRE1-XBP1 pathway regulates oxidative proinsulin folding in pancreatic β cells. (Q52728755) (← links)
• The nucleotide exchange factor SIL1 is required for glucose-stimulated insulin secretion from mouse pancreatic beta cells in vivo (Q58185753) (← links)