Pages that link to "Q33376941"
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The following pages link to The pharmacokinetics, toxicities, and biologic effects of FK866, a nicotinamide adenine dinucleotide biosynthesis inhibitor (Q33376941):
Displaying 50 items.
- Novel drugs that target the metabolic reprogramming in renal cell cancer (Q26740187) (← links)
- New strategies to maximize therapeutic opportunities for NAMPT inhibitors in oncology (Q26745678) (← links)
- Research into cancer metabolomics: Towards a clinical metamorphosis (Q26781245) (← links)
- Cancer metabolic reprogramming: importance, main features, and potentials for precise targeted anti-cancer therapies (Q26823118) (← links)
- A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPT (Q27656939) (← links)
- Structural and biochemical analyses of the catalysis and potency impact of inhibitor phosphoribosylation by human nicotinamide phosphoribosyltransferase (Q27690154) (← links)
- Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells (Q28476348) (← links)
- [18F]FLT and [18F]FDG PET for non-invasive treatment monitoring of the nicotinamide phosphoribosyltransferase inhibitor APO866 in human xenografts (Q28484852) (← links)
- NAMPT-mediated salvage synthesis of NAD controls morphofunctional changes of macrophages (Q28538761) (← links)
- Metabolomics analysis of metabolic effects of nicotinamide phosphoribosyltransferase (NAMPT) inhibition on human cancer cells (Q28542558) (← links)
- Structural basis for resistance to diverse classes of NAMPT inhibitors (Q28543568) (← links)
- Catastrophic NAD depletion in activated T lymphocytes through Nampt inhibition reduces demyelination and disability in EAE. (Q30912415) (← links)
- Preclinical models of nicotinamide phosphoribosyltransferase inhibitor-mediated hematotoxicity and mitigation by co-treatment with nicotinic acid (Q33422176) (← links)
- A critical role of autophagy in antileukemia/lymphoma effects of APO866, an inhibitor of NAD biosynthesis (Q33878859) (← links)
- Characterization of NAD uptake in mammalian cells (Q34009257) (← links)
- Nicotinamide phosphoribosyltransferase inhibitor is a novel therapeutic candidate in murine models of inflammatory lung injury (Q34103687) (← links)
- Nicotinamide phosphoribosyl transferase (Nampt) is required for de novo lipogenesis in tumor cells (Q34328772) (← links)
- Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase. (Q34482044) (← links)
- Next-generation NAMPT inhibitors identified by sequential high-throughput phenotypic chemical and functional genomic screens (Q35030829) (← links)
- New function for Escherichia coli xanthosine phophorylase (xapA): genetic and biochemical evidences on its participation in NAD( ) salvage from nicotinamide (Q35088919) (← links)
- Discovery and characterization of novel small-molecule inhibitors targeting nicotinamide phosphoribosyltransferase (Q35652041) (← links)
- Discovery of Novel Inhibitors and Fluorescent Probe Targeting NAMPT. (Q35727985) (← links)
- NAD levels control Ca2 store replenishment and mitogen-induced increase of cytosolic Ca2 by Cyclic ADP-ribose-dependent TRPM2 channel gating in human T lymphocytes (Q36033195) (← links)
- Pharmacological inhibition of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme essential for NAD biosynthesis, in human cancer cells: metabolic basis and potential clinical implications (Q36579595) (← links)
- Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model (Q36771997) (← links)
- Intracellular NAD⁺ depletion enhances bortezomib-induced anti-myeloma activity (Q37098847) (← links)
- CD73 protein as a source of extracellular precursors for sustained NAD biosynthesis in FK866-treated tumor cells (Q37151029) (← links)
- Dependence of tumor cell lines and patient-derived tumors on the NAD salvage pathway renders them sensitive to NAMPT inhibition with GNE-618 (Q37285546) (← links)
- How to live long and prosper: autophagy, mitochondria, and aging (Q37300834) (← links)
- Regulation of inflammatory cytokine expression in pulmonary epithelial cells by pre-B-cell colony-enhancing factor via a nonenzymatic and AP-1-dependent mechanism (Q37448001) (← links)
- Supplementation of nicotinic acid with NAMPT inhibitors results in loss of in vivo efficacy in NAPRT1-deficient tumor models. (Q37448050) (← links)
- A pancreatic ductal adenocarcinoma subpopulation is sensitive to FK866, an inhibitor of NAMPT. (Q37619827) (← links)
- Targeting of NAD metabolism in pancreatic cancer cells: potential novel therapy for pancreatic tumors. (Q37626233) (← links)
- MC-PPEA as a new and more potent inhibitor of CLP-induced sepsis and pulmonary inflammation than FK866. (Q37691630) (← links)
- Inhibition of Nicotinamide Phosphoribosyltransferase Induces Apoptosis in Estrogen Receptor-Positive MCF-7 Breast Cancer Cells (Q37735953) (← links)
- Metabolic and molecular insights into an essential role of nicotinamide phosphoribosyltransferase (Q37745422) (← links)
- Targeting cancer metabolism: a therapeutic window opens (Q37924094) (← links)
- PBEF/NAMPT/visfatin: a promising drug target for treating rheumatoid arthritis? (Q38005192) (← links)
- The NAD metabolome--a key determinant of cancer cell biology (Q38047182) (← links)
- EWS-FLI1 confers exquisite sensitivity to NAMPT inhibition in Ewing sarcoma cells (Q38405687) (← links)
- Physiological and pathophysiological roles of NAMPT and NAD metabolism (Q38555243) (← links)
- Crystal structure-based comparison of two NAMPT inhibitors (Q38635017) (← links)
- Intracellular NAD levels are associated with LPS-induced TNF-α release in pro-inflammatory macrophages. (Q38668587) (← links)
- Cardiotoxicity Associated with Nicotinamide Phosphoribosyltransferase Inhibitors in Rodents and in Rat and Human-Derived Cells Lines. (Q38736710) (← links)
- Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is a tumoural cytokine released from melanoma (Q38836229) (← links)
- NAMPT inhibition sensitizes pancreatic adenocarcinoma cells to tumor-selective, PAR-independent metabolic catastrophe and cell death induced by β-lapachone. (Q38919749) (← links)
- Retinal toxicity, in vivo and in vitro, associated with inhibition of nicotinamide phosphoribosyltransferase. (Q38928592) (← links)
- Nicotinamide Phosphoribosyltransferase Promotes Pulmonary Vascular Remodeling and Is a Therapeutic Target in Pulmonary Arterial Hypertension (Q38986359) (← links)
- Nicotinamide phosphoribosyltransferase (Nampt) affects the lineage fate determination of mesenchymal stem cells: A possible cause for reduced osteogenesis and increased adipogenesis in older individuals (Q39496015) (← links)
- Expression patterns of nicotinamide phosphoribosyltransferase and nicotinic acid phosphoribosyltransferase in human malignant lymphomas. (Q39558774) (← links)