Pages that link to "Q30659857"
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The following pages link to Novel CFTR chloride channel activators identified by screening of combinatorial libraries based on flavone and benzoquinolizinium lead compounds (Q30659857):
Displaying 50 items.
- Therapeutic Rescue of Misfolded Mutants: Validation of Primary High Throughput Screens for Identification of Pharmacoperone Drugs (Q21089948) (← links)
- Pharmacoperone Identification for Therapeutic Rescue of Misfolded Mutant Proteins (Q21131288) (← links)
- Chloride channels as drug targets (Q24601830) (← links)
- High throughput screening technologies for ion channels (Q26776486) (← links)
- CFTR Modulators: Shedding Light on Precision Medicine for Cystic Fibrosis (Q28073996) (← links)
- Inhibition of ANO1/TMEM16A Chloride Channel by Idebenone and Its Cytotoxicity to Cancer Cell Lines (Q28546722) (← links)
- Potentiation of ΔF508- and G551D-CFTR-Mediated Cl- Current by Novel Hydroxypyrazolines (Q28550065) (← links)
- Ani9, A Novel Potent Small-Molecule ANO1 Inhibitor with Negligible Effect on ANO2 (Q28552360) (← links)
- Expression and function of epithelial anoctamins (Q28591748) (← links)
- Trafficking and quality control of the gonadotropin releasing hormone receptor in health and disease (Q28755163) (← links)
- Monomeric CFTR in plasma membranes in live cells revealed by single molecule fluorescence imaging (Q30483292) (← links)
- Small molecule correctors of F508del-CFTR discovered by structure-based virtual screening (Q30577535) (← links)
- Cellular Fluorescent Indicators and Voltage/Ion Probe Reader (VIPR TM ): Tools for Ion Channel and Receptor Drug Discovery (Q31138101) (← links)
- A phenotypic high throughput screening assay for the identification of pharmacoperones for the gonadotropin releasing hormone receptor (Q33629937) (← links)
- Cystic fibrosis: exploiting its genetic basis in the hunt for new therapies (Q33664918) (← links)
- Transitioning pharmacoperones to therapeutic use: in vivo proof-of-principle and design of high throughput screens. (Q33717398) (← links)
- Chloride channel inhibition by a red wine extract and a synthetic small molecule prevents rotaviral secretory diarrhoea in neonatal mice (Q33723721) (← links)
- Identification of Synergistic Combinations of F508del Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Modulators (Q33738057) (← links)
- Optimization of a Yellow Fluorescent Protein-Based Iodide Influx High-Throughput Screening Assay for Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Modulators (Q33738063) (← links)
- Phenylquinoxalinone CFTR activator as potential prosecretory therapy for constipation (Q33752154) (← links)
- New horizons in the treatment of cystic fibrosis (Q33756002) (← links)
- Using pharmacological chaperones to restore proteostasis (Q33804655) (← links)
- Small-molecule correctors of defective DeltaF508-CFTR cellular processing identified by high-throughput screening. (Q33925348) (← links)
- Direct effects of 9-anthracene compounds on cystic fibrosis transmembrane conductance regulator gating (Q33947514) (← links)
- Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion. (Q34162541) (← links)
- A sensitive membrane-targeted biosensor for monitoring changes in intracellular chloride in neuronal processes (Q34233878) (← links)
- Cysteine transport through excitatory amino acid transporter 3 (EAAT3). (Q34282413) (← links)
- CFTR chloride channel in the apical compartments: spatiotemporal coupling to its interacting partners (Q34340439) (← links)
- Pharmacological Correctors of Mutant CFTR Mistrafficking (Q34444239) (← links)
- Novel amino-carbonitrile-pyrazole identified in a small molecule screen activates wild-type and ΔF508 cystic fibrosis transmembrane conductance regulator in the absence of a cAMP agonist (Q34780067) (← links)
- Microfluidics platform for single-shot dose-response analysis of chloride channel-modulating compounds (Q34888430) (← links)
- Disease genes: flattery and deception (Q34987529) (← links)
- Ion transport mechanisms linked to bicarbonate secretion in the esophageal submucosal glands (Q35086913) (← links)
- Pharmacological Chaperones for Misfolded Gonadotropin-Releasing Hormone Receptors (Q35606973) (← links)
- Resveratrol ameliorates abnormalities of fluid and electrolyte secretion in a hypoxia-Induced model of acquired CFTR deficiency (Q35623246) (← links)
- Pharmacological approaches to correcting the ion transport defect in cystic fibrosis (Q35627639) (← links)
- Drug discovery in academia (Q35648435) (← links)
- Assay strategies for identification of therapeutic leads that target protein trafficking (Q35661403) (← links)
- CFTR regulation in human airway epithelial cells requires integrity of the actin cytoskeleton and compartmentalized cAMP and PKA activity (Q35883884) (← links)
- Macromolecular interactions and ion transport in cystic fibrosis (Q35901540) (← links)
- Pharmacologic rescue of conformationally-defective proteins: implications for the treatment of human disease (Q35915771) (← links)
- Pharmacological Rescue of the Mutant Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Detected by Use of a Novel Fluorescence Platform (Q36071699) (← links)
- Improved fluorescence assays to measure the defects associated with F508del-CFTR allow identification of new active compounds (Q36251047) (← links)
- G551D and G1349D, two CF-associated mutations in the signature sequences of CFTR, exhibit distinct gating defects (Q36296010) (← links)
- Channel Gating Regulation by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) First Cytosolic Loop (Q36489303) (← links)
- Targeting the Intracellular Environment in Cystic Fibrosis: Restoring Autophagy as a Novel Strategy to Circumvent the CFTR Defect (Q36547077) (← links)
- Targeted therapy for cystic fibrosis: cystic fibrosis transmembrane conductance regulator mutation-specific pharmacologic strategies (Q36615230) (← links)
- Local modulation of cystic fibrosis conductance regulator: cytoskeleton and compartmentalized cAMP signalling (Q36783966) (← links)
- Small-molecule CFTR activators increase tear secretion and prevent experimental dry eye disease (Q36812082) (← links)
- CFTR activator increases intestinal fluid secretion and normalizes stool output in a mouse model of constipation (Q36833766) (← links)