Pages that link to "Q24676047"
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The following pages link to Thiopurine S-methyltransferase deficiency: two nucleotide transitions define the most prevalent mutant allele associated with loss of catalytic activity in Caucasians (Q24676047):
Displaying 50 items.
- Very important pharmacogene summary: thiopurine S-methyltransferase (Q24601748) (← links)
- Enhanced proteolysis of thiopurine S-methyltransferase (TPMT) encoded by mutant alleles in humans (TPMT*3A, TPMT*2): mechanisms for the genetic polymorphism of TPMT activity (Q24682894) (← links)
- A health-care system perspective on implementing genomic medicine: pediatric acute lymphoblastic leukemia as a paradigm (Q26866379) (← links)
- Using Germline Genomics to Individualize Pediatric Cancer Treatments (Q27003261) (← links)
- Structural basis of allele variation of human thiopurine-S-methyltransferase (Q27643631) (← links)
- Pharmacogenomics in Pediatric Oncology: Review of Gene-Drug Associations for Clinical Use (Q28068930) (← links)
- Personalization of the immunosuppressive treatment in renal transplant recipients: the great challenge in "omics" medicine (Q28082746) (← links)
- NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity (Q28115755) (← links)
- Thiopurine methyltransferase (TPMT) genotype distribution in azathioprine-tolerant and -intolerant patients with various disorders. The impact of TPMT genotyping in predicting toxicity (Q28186720) (← links)
- Pharmacogenomics: the promise of personalized medicine (Q28210286) (← links)
- Promoter and intronic sequences of the human thiopurine S-methyltransferase (TPMT) gene isolated from a human PAC1 genomic library (Q28260851) (← links)
- Genetic polymorphisms of human flavin-containing monooxygenase 3: implications for drug metabolism and clinical perspectives (Q28305656) (← links)
- Frequencies of thiopurine S-methyltransferase mutant alleles (TPMT*2, *3A, *3B and *3C) in 151 healthy Japanese subjects and the inheritance of TPMT*3C in the family of a propositus (Q28367534) (← links)
- Pharmacogenomic discovery using cell-based models (Q28392982) (← links)
- Assessment of Thiopurine-based drugs according to Thiopurine S-methyltransferase genotype in patients with Acute Lymphoblastic Leukemia (Q28612763) (← links)
- Four human thiopurine s-methyltransferase alleles severely affect protein structure and dynamics (Q30369449) (← links)
- Genes implicated in thiopurine-induced toxicity: Comparing TPMT enzyme activity with clinical phenotype and exome data in a paediatric IBD cohort. (Q31134780) (← links)
- Pharmacogenetics as a molecular basis for individualized drug therapy: the thiopurine S-methyltransferase paradigm (Q33600016) (← links)
- Pharmacogenomics. Interview by Clare Thompson (Q33821420) (← links)
- Pharmacogenetics: a tool for individualizing antineoplastic therapy (Q34099799) (← links)
- Thiopurine Methyltransferase Predicts the Extent of Cytotoxicty and DNA Damage in Astroglial Cells after Thioguanine Exposure (Q34117269) (← links)
- Ecto-5'-nucleotidase and thiopurine cellular circulation: association with cytotoxicity (Q34359524) (← links)
- Pharmacogenetics of Cancer Therapy: Getting Personal (Q34386321) (← links)
- Pharmacogenetics: the therapeutic drug monitoring of the future? (Q34458332) (← links)
- Clinical pharmacology and pharmacogenetics of thiopurines (Q34782066) (← links)
- Clinically Relevant Genetic Variations in Drug Metabolizing Enzymes (Q35032378) (← links)
- Pharmacogenomics: marshalling the human genome to individualise drug therapy (Q35090217) (← links)
- Polymorphisms of the thiopurine S-methyltransferase gene among the Libyan population (Q35225364) (← links)
- Thiopurine S-methyltransferase genetic polymorphism in the Thai population (Q35826222) (← links)
- Phenotyping and genotyping study of thiopurine S-methyltransferase in healthy Chinese children: a comparison of Han and Yao ethnic groups (Q35826329) (← links)
- Thiopurine methyltransferase activity and its relationship to the occurrence of rejection episodes in paediatric renal transplant recipients treated with azathioprine (Q36053671) (← links)
- The thiopurines: an update (Q36305435) (← links)
- Pharmacogenetics and diseases of the colon (Q36404764) (← links)
- Genetic polymorphisms of drug-metabolising enzymes and drug transporters in the chemotherapeutic treatment of cancer (Q36410400) (← links)
- High-resolution melting analysis of the TPMT gene: a study in the Polish population. (Q36553971) (← links)
- Pharmacogenomics in pediatric leukemia (Q36727952) (← links)
- Nomenclature for alleles of the thiopurine methyltransferase gene (Q37056505) (← links)
- Pharmacogenetics of Drug Metabolizing Enzymes and Transporters: Effects on Pharmacokinetics and Pharmacodynamics of Anticancer Agents (Q37163352) (← links)
- TPMT*26 (208F-->L), a novel mutation detected in a Chinese (Q37321444) (← links)
- Human thiopurine methyltransferase pharmacogenetics. Kindred with a terminal exon splice junction mutation that results in loss of activity (Q37378665) (← links)
- Pharmacogenomic progress in individualized dosing of key drugs for cancer patients (Q37378994) (← links)
- Genetic polymorphism of inosine triphosphate pyrophosphatase is a determinant of mercaptopurine metabolism and toxicity during treatment for acute lymphoblastic leukemia (Q37388537) (← links)
- TPMT genetic variations in populations of the Russian Federation. (Q37477625) (← links)
- Advances in the diagnosis and management of inflammatory bowel disease: challenges and uncertainties. (Q37703514) (← links)
- Part 1: background, methodology, and clinical adoption of pharmacogenetics (Q37883726) (← links)
- Part 3: Pharmacogenetic Variability in Phase II Anticancer Drug Metabolism (Q37887337) (← links)
- Pharmacogenetics: implications for therapy in rheumatic diseases (Q37913989) (← links)
- One amino acid makes a difference-Characterization of a new TPMT allele and the influence of SAM on TPMT stability (Q38809535) (← links)
- Genotype and allele frequencies of TPMT, NAT2, GST, SULT1A1 and MDR-1 in the Egyptian population (Q39042848) (← links)
- Comparison of Direct Sequencing, Real-Time PCR-High Resolution Melt (PCR-HRM) and PCR-Restriction Fragment Length Polymorphism (PCR-RFLP) Analysis for Genotyping of Common Thiopurine Intolerant Variant Alleles NUDT15 c.415C>T and TPMT c.719A>G (TPMT (Q41008729) (← links)