Pages that link to "Q24324144"

The following pages link to Bcr-Abl oncoproteins bind directly to activators of the Ras signalling pathway (Q24324144):

Displaying 50 items.

• BCR activator of RhoGEF and GTPase (Q903924) (← links)
• Growth factor receptor bound protein 2 (Q5514416) (← links)
• The product of the cbl oncogene forms stable complexes in vivo with endogenous Crk in a tyrosine phosphorylation-dependent manner (Q24310761) (← links)
• Protein tyrosine phosphatase 1B antagonizes signalling by oncoprotein tyrosine kinase p210 bcr-abl in vivo (Q24311296) (← links)
• Molecular cloning and characterization of p56dok-2 defines a new family of RasGAP-binding proteins (Q24312189) (← links)
• Grap is a novel SH3-SH2-SH3 adaptor protein that couples tyrosine kinases to the Ras pathway (Q24315873) (← links)
• Rapid identification of phosphopeptide ligands for SH2 domains. Screening of peptide libraries by fluorescence-activated bead sorting (Q24321244) (← links)
• The CRKL adaptor protein transforms fibroblasts and functions in transformation by the BCR-ABL oncogene (Q24321680) (← links)
• Co-expression with BCR induces activation of the FES tyrosine kinase and phosphorylation of specific N-terminal BCR tyrosine residues (Q24336377) (← links)
• A direct binding site for Grb2 contributes to transformation and leukemogenesis by the Tel-Abl (ETV6-Abl) tyrosine kinase (Q24563301) (← links)
• Wiskott-Aldrich syndrome protein is associated with the adapter protein Grb2 and the epidermal growth factor receptor in living cells (Q24599228) (← links)
• Tyrosine phosphorylation of BCR by FPS/FES protein-tyrosine kinases induces association of BCR with GRB-2/SOS (Q24646851) (← links)
• Molecular mechanisms for survival regulation of chronic myeloid leukemia stem cells (Q26828528) (← links)
• Kinase-independent mechanisms of resistance of leukemia stem cells to tyrosine kinase inhibitors (Q26849792) (← links)
• Signal transduction in the chronic leukemias: implications for targeted therapies (Q27026031) (← links)
• Signaling via Shc family adapter proteins (Q28199357) (← links)
• The interaction of the Bcr-Abl tyrosine kinase with the Src kinase Hck is mediated by multiple binding domains (Q28210453) (← links)
• Tyrosine phosphorylation of Grb2 by Bcr/Abl and epidermal growth factor receptor: a novel regulatory mechanism for tyrosine kinase signaling (Q28365521) (← links)
• Modeling of molecular interaction between apoptin, BCR-Abl and CrkL--an alternative approach to conventional rational drug design (Q28478748) (← links)
• Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia (Q28505914) (← links)
• Inhibition of class II phosphoinositide 3-kinase gamma expression by p185(Bcr-Abl) contributes to impaired chemotaxis and aberrant homing of leukemic cells (Q28512494) (← links)
• A novel pathway from phosphorylation of tyrosine residues 239/240 of Shc, contributing to suppress apoptosis by IL-3 (Q28609040) (← links)
• Critical role for Gab2 in transformation by BCR/ABL (Q28610046) (← links)
• Icaritin Shows Potent Anti-Leukemia Activity on Chronic Myeloid Leukemia In Vitro and In Vivo by Regulating MAPK/ERK/JNK and JAK2/STAT3 /AKT Signalings (Q28741022) (← links)
• SH2 and SH3 domains as targets for anti-proliferative agents (Q30167833) (← links)
• The role of Gads in hematopoietic cell signalling. (Q30167860) (← links)
• Involvement of Jak2 tyrosine phosphorylation in Bcr-Abl transformation (Q30167883) (← links)
• Dynamin inhibits phosphatidylinositol 3-kinase in hematopoietic cells. (Q30168193) (← links)
• Grb2 promotes reinitiation of meiosis in Xenopus oocytes. (Q30168392) (← links)
• Bcr-Abl with an SH3 deletion retains the ability To induce a myeloproliferative disease in mice, yet c-Abl activated by an SH3 deletion induces only lymphoid malignancy (Q30175351) (← links)
• Mammalian Grb2 regulates multiple steps in embryonic development and malignant transformation. (Q30175931) (← links)
• Regulation of the oncogenic activity of BCR-ABL by a tightly bound substrate protein RIN1. (Q30176527) (← links)
• Activation of the JNK pathway is essential for transformation by the Met oncogene (Q30176542) (← links)
• Mutant forms of growth factor-binding protein-2 reverse BCR-ABL-induced transformation (Q30192925) (← links)
• The Grb2 adaptor (Q30193221) (← links)
• Growth advantage of chronic myeloid leukemia CFU-GM in vitro: survival to growth factor deprivation, possibly related to autocrine stimulation, is a more common feature than hypersensitivity to GM-CSF/IL3 and is efficiently counteracted by retinoids (Q32118893) (← links)
• Subcellular distribution of p210(BCR-ABL) in CML cell lines and primary CD34 CML cells (Q33308579) (← links)
• In vitro antiproliferative activity of the farnesyltransferase inhibitor R115777 in hematopoietic progenitors from patients with myelofibrosis with myeloid metaplasia (Q33348021) (← links)
• A BCR-ABL mutant lacking direct binding sites for the GRB2, CBL and CRKL adapter proteins fails to induce leukemia in mice (Q33510153) (← links)
• Farnesyltransferase inhibitors: targeting the molecular basis of cancer (Q33670187) (← links)
• The Bcr-Abl leukemia oncogene activates Jun kinase and requires Jun for transformation (Q33720267) (← links)
• The carboxyl terminus of v-Abl protein can augment SH2 domain function (Q33804134) (← links)
• Ceramide promotes apoptosis in chronic myelogenous leukemia-derived K562 cells by a mechanism involving caspase-8 and JNK (Q33810952) (← links)
• A genome-wide survey of RAS transformation targets (Q33888438) (← links)
• Mechanisms of transformation by the BCR/ABL oncogene (Q33946147) (← links)
• Profiling the global tyrosine phosphorylation state by Src homology 2 domain binding (Q33949818) (← links)
• The NH(2)-terminal coiled-coil domain and tyrosine 177 play important roles in induction of a myeloproliferative disease in mice by Bcr-Abl (Q33967112) (← links)
• Expression of a Src family kinase in chronic myelogenous leukemia cells induces resistance to imatinib in a kinase-dependent manner (Q33967180) (← links)
• SH2 domain specificity and activity modified by a single residue (Q34057752) (← links)
• Destabilization of Bcr-Abl/Jak2 Network by a Jak2/Abl Kinase Inhibitor ON044580 Overcomes Drug Resistance in Blast Crisis Chronic Myelogenous Leukemia (CML) (Q34082540) (← links)