Probing the Dynamics of AcrB Through Disulfide Bond Formation (Q99241187)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32905396 AND SRC:MED&resulttype=core&format=json

12 September 2020

title

Probing the Dynamics of AcrB Through Disulfide Bond Formation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32905396 AND SRC:MED&resulttype=core&format=json

12 September 2020

author name string

Prasangi Rajapaksha

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32905396 AND SRC:MED&resulttype=core&format=json

12 September 2020

Ankit Pandeya

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32905396 AND SRC:MED&resulttype=core&format=json

12 September 2020

Yinan Wei

series ordinal

3

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12 September 2020

publication date

20 August 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32905396 AND SRC:MED&resulttype=core&format=json

12 September 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32905396 AND SRC:MED&resulttype=core&format=json

12 September 2020

volume

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32905396 AND SRC:MED&resulttype=core&format=json

12 September 2020

issue

34

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12 September 2020

page(s)

21844-21852

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32905396 AND SRC:MED&resulttype=core&format=json

AcrB: a mean, keen, drug efflux machine

12 September 2020

cites work

1 reference

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In situ structure and assembly of the multidrug efflux pump AcrAB-TolC.

10 February 2021

1 reference

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Molecular mechanisms of AcrB-mediated multidrug export

10 February 2021

1 reference

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Minireview: CLSI Methods Development and Standardization Working Group Best Practices for the Evaluation of Antimicrobial Susceptibility Tests

10 February 2021

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Water-mediated interactions enable smooth substrate transport in a bacterial efflux pump

10 February 2021

1 reference

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Multiple entry pathways within the efflux transporter AcrB contribute to multidrug recognition.

10 February 2021

1 reference

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Energy coupling mechanisms of AcrB-like RND transporters

10 February 2021

1 reference

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Using a SMALP platform to determine a sub-nm single particle cryo-EM membrane protein structure.

10 February 2021

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An allosteric transport mechanism for the AcrAB-TolC multidrug efflux pump

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Transport of lipophilic carboxylates is mediated by transmembrane helix 2 in multidrug transporter AcrB.

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Tripartite assembly of RND multidrug efflux pumps.

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Structure of the tripartite multidrug efflux pump AcrAB-TolC suggests an alternative assembly mode

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

The challenge of efflux-mediated antibiotic resistance in Gram-negative bacteria

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Cysteine residue is not essential for CPM protein thermal-stability assay.

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Structure of the AcrAB–TolC multidrug efflux pump

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Functional relevance of AcrB Trimerization in pump assembly and substrate binding

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Disulfide by Design 2.0: a web-based tool for disulfide engineering in proteins

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Fiji: an open-source platform for biological-image analysis

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

AcrB trimer stability and efflux activity, insight from mutagenesis studies

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

A Reporter Platform for the Monitoring of In Vivo Conformational Changes in AcrB

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Site-Directed Disulfide Cross-Linking to Probe Conformational Changes of a Transporter During Its Functional Cycle: Escherichia coli AcrB Multidrug Exporter as an Example

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Functional rotation of the transporter AcrB: insights into drug extrusion from simulations

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Fluorometric determination of ethidium bromide efflux kinetics in Escherichia coli

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Covalently linked trimer of the AcrB multidrug efflux pump provides support for the functional rotating mechanism

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

The AcrB efflux pump: conformational cycling and peristalsis lead to multidrug resistance

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Multidrug efflux transporter, AcrB--the pumping mechanism

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Engineered disulfide bonds support the functional rotation mechanism of multidrug efflux pump AcrB.

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Crystal structure of AcrB in complex with a single transmembrane subunit reveals another twist

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Site-directed disulfide cross-linking shows that cleft flexibility in the periplasmic domain is needed for the multidrug efflux pump AcrB of Escherichia coli

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Crystal structure of the multidrug efflux transporter AcrB at 3.1Å resolution reveals the N-terminal region with conserved amino acids

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Drug export pathway of multidrug exporter AcrB revealed by DARPin inhibitors

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Structural asymmetry of AcrB trimer suggests a peristaltic pump mechanism

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Crystal structures of a multidrug transporter reveal a functionally rotating mechanism.

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Three's company: component structures bring a closer view of tripartite drug efflux pumps.

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Crystallographic analysis of AcrB.

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Extramembrane central pore of multidrug exporter AcrB in Escherichia coli plays an important role in drug transport

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Crystal structure of bacterial multidrug efflux transporter AcrB

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Antibiotic susceptibility profiles of Escherichia coli strains lacking multidrug efflux pump genes

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Multidrug resistance mechanisms: drug efflux across two membranes

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Multiple antibiotic resistance and efflux

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

Multidrug efflux pumps of gram-negative bacteria

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7469415

10 February 2021

Identifiers

DOI

10.1021/ACSOMEGA.0C02921

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32905396 AND SRC:MED&resulttype=core&format=json

12 September 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32905396 AND SRC:MED&resulttype=core&format=json

12 September 2020

PubMed publication ID

32905396

1 reference