Polymorphic Region-Specific Antibody for Evaluation of Affinity-Associated Profile of Chimeric Antigen Receptor (Q94528313)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32368617 AND SRC:MED&resulttype=core&format=json

15 May 2020

title

Polymorphic Region-Specific Antibody for Evaluation of Affinity-Associated Profile of Chimeric Antigen Receptor (English)

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15 May 2020

10

Hyeon-Seok Eom

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15 May 2020

author name string

Chungyong Han

1

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15 May 2020

Beom K Choi

2

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15 May 2020

Seon-Hee Kim

3

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15 May 2020

Su-Jung Sim

4

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15 May 2020

Seongeun Han

5

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15 May 2020

Bomi Park

6

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15 May 2020

Yohei Tsuchiya

7

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15 May 2020

Masaki Takahashi

8

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15 May 2020

Young H Kim

9

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15 May 2020

Tetsuya Kitaguchi

11

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15 May 2020

Hiroshi Ueda

12

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15 May 2020

Byoung S Kwon

13

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15 May 2020

publication date

14 April 2020

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Molecular therapy oncolytics

15 May 2020

published in

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volume

17

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15 May 2020

page(s)

293-305

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Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR

15 May 2020

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Chimeric antigen receptor T cells form nonclassical and potent immune synapses driving rapid cytotoxicity

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Micromolar affinity CAR T cells to ICAM-1 achieves rapid tumor elimination while avoiding systemic toxicity

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Tonic 4-1BB Costimulation in Chimeric Antigen Receptors Impedes T Cell Survival and Is Vector-Dependent

11 February 2021

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Function of Novel Anti-CD19 Chimeric Antigen Receptors with Human Variable Regions Is Affected by Hinge and Transmembrane Domains

11 February 2021

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A Rational Strategy for Reducing On-Target Off-Tumor Effects of CD38-Chimeric Antigen Receptors by Affinity Optimization.

11 February 2021

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Balance of Anti-CD123 Chimeric Antigen Receptor Binding Affinity and Density for the Targeting of Acute Myeloid Leukemia

11 February 2021

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New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management

11 February 2021

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Cell-Binding Assays for Determining the Affinity of Protein-Protein Interactions: Technologies and Considerations

11 February 2021

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Polyfunctional Melan-A-specific tumor-reactive CD8( ) T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOS.

11 February 2021

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Bispecific antibodies and CARs: generalized immunotherapeutics harnessing T cell redirection

11 February 2021

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Affinity-Tuned ErbB2 or EGFR Chimeric Antigen Receptor T Cells Exhibit an Increased Therapeutic Index against Tumors in Mice

11 February 2021

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Tuning Sensitivity of CAR to EGFR Density Limits Recognition of Normal Tissue While Maintaining Potent Antitumor Activity

11 February 2021

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A T-cell-directed chimeric antigen receptor for the selective treatment of T-cell malignancies

11 February 2021

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4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors

11 February 2021

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Functional Tuning of CARs Reveals Signaling Threshold above Which CD8 CTL Antitumor Potency Is Attenuated due to Cell Fas-FasL-Dependent AICD.

11 February 2021

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The IPD and IMGT/HLA database: allele variant databases

11 February 2021

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The nonsignaling extracellular spacer domain of chimeric antigen receptors is decisive for in vivo antitumor activity.

11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit

11 February 2021

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11 February 2021

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VH and VL gene analysis in sporadic Burkitt's lymphoma shows somatic hypermutation, intraclonal heterogeneity, and a role for antigen selection

11 February 2021

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Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

11 February 2021

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Activation and proliferation of follicular dendritic cell-like cells by activated T lymphocytes

11 February 2021

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10.1016/J.OMTO.2020.04.004

11 February 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32368617 AND SRC:MED&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32368617 AND SRC:MED&resulttype=core&format=json

15 May 2020

PubMed publication ID

32368617

1 reference