A phase I study of single-agent BEZ235 special delivery system sachet in Japanese patients with advanced solid tumors (Q93184786)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30446785 AND SRC:MED&resulttype=core&format=json

4 May 2020

title

A phase I study of single-agent BEZ235 special delivery system sachet in Japanese patients with advanced solid tumors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30446785 AND SRC:MED&resulttype=core&format=json

4 May 2020

author name string

Masanori Toyoda

1

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4 May 2020

Koichiro Watanabe

2

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4 May 2020

Taro Amagasaki

3

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4 May 2020

Kazuto Natsume

4

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4 May 2020

Hiromi Takeuchi

5

1 reference

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4 May 2020

Cornelia Quadt

6

1 reference

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4 May 2020

publication date

16 November 2018

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Cancer Chemotherapy and Pharmacology

4 May 2020

published in

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4 May 2020

volume

83

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4 May 2020

issue

2

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4 May 2020

page(s)

289-299

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Creative Commons Attribution 4.0 International

4 May 2020

copyright license

start time

16 November 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Phase 1/1b dose escalation and expansion study of BEZ235, a dual PI3K/mTOR inhibitor, in patients with advanced solid tumors including patients with advanced breast cancer

1 reference

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A Phase Ib Study of BEZ235, a Dual Inhibitor of Phosphatidylinositol 3-Kinase (PI3K) and Mammalian Target of Rapamycin (mTOR), in Patients With Advanced Renal Cell Carcinoma

11 February 2021

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A phase 1 study of the sachet formulation of the oral dual PI3K/mTOR inhibitor BEZ235 given twice daily (BID) in patients with advanced solid tumors

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6394493

A Translational, Pharmacodynamic, and Pharmacokinetic Phase IB Clinical Study of Everolimus in Resectable Non-Small Cell Lung Cancer

11 February 2021

1 reference

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Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity

11 February 2021

1 reference

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Simultaneous inhibition of PDK1/AKT and Fms-like tyrosine kinase 3 signaling by a small-molecule KP372-1 induces mitochondrial dysfunction and apoptosis in acute myelogenous leukemia

11 February 2021

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PTEN function in normal and neoplastic growth

11 February 2021

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Genetic pathways to glioblastomas

11 February 2021

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

11 February 2021

1 reference

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Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic

11 February 2021

1 reference

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10.1007/S00280-018-3725-2

11 February 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30446785 AND SRC:MED&resulttype=core&format=json

4 May 2020

1 reference

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4 May 2020

PubMed publication ID

30446785

1 reference