Low-Dose Decitabine Assists Human Umbilical Cord-Derived Mesenchymal Stem Cells in Protecting β Cells via the Modulation of the Macrophage Phenotype in Type 2 Diabetic Mice (Q93165383)

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scientific article published on 03 April 2020

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English	Low-Dose Decitabine Assists Human Umbilical Cord-Derived Mesenchymal Stem Cells in Protecting β Cells via the Modulation of the Macrophage Phenotype in Type 2 Diabetic Mice	scientific article published on 03 April 2020

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4 May 2020

Low-Dose Decitabine Assists Human Umbilical Cord-Derived Mesenchymal Stem Cells in Protecting β Cells via the Modulation of the Macrophage Phenotype in Type 2 Diabetic Mice (English)

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human umbilical cord mesenchymal stem cell

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Yu Cheng

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Haojie Hao

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Jieqing Gao

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Yaqi Yin

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Songyan Yu

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Junyan Zou

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Jiejie Liu

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Qi Zhang

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3 April 2020

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Stem Cells International

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4 May 2020

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3 April 2020

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Human umbilical cord-derived mesenchymal stem cells direct macrophage polarization to alleviate pancreatic islets dysfunction in type 2 diabetic mice

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Long term effect and safety of Wharton's jelly-derived mesenchymal stem cells on type 2 diabetes

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Mesenchymal stromal cells induce peculiar alternatively activated macrophages capable of dampening both innate and adaptive immune responses.

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Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation

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Human umbilical cord-derived mesenchymal stem cells elicit macrophages into an anti-inflammatory phenotype to alleviate insulin resistance in type 2 diabetic rats.

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LPS-preconditioned mesenchymal stromal cells modify macrophage polarization for resolution of chronic inflammation via exosome-shuttled let-7b

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Decitabine Enhances Lymphocyte Migration and Function and Synergizes with CTLA-4 Blockade in a Murine Ovarian Cancer Model.

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Minireview: Emerging Concepts in Islet Macrophage Biology in Type 2 Diabetes

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Therapeutic efficacy and biodistribution of allogeneic mesenchymal stem cells delivered by intrasplenic and intrapancreatic routes in streptozotocin-induced diabetic mice.

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Concise Review: Macrophages: Versatile Gatekeepers During Pancreatic β-Cell Development, Injury, and Regeneration.

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Umbilical cord mesenchymal stem cell transfusion ameliorated hyperglycemia in patients with type 2 diabetes mellitus.

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A Novel Long-Acting Glucagon-Like Peptide-1 Agonist with Improved Efficacy in Insulin Secretion and β-Cell Growth

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Niche-dependent regulations of metabolic balance in high-fat diet-induced diabetic mice by mesenchymal stromal cells

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Inhibiting DNA Methylation by 5-Aza-2'-deoxycytidine ameliorates atherosclerosis through suppressing macrophage inflammation.

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Decitabine, a new star in epigenetic therapy: the clinical application and biological mechanism in solid tumors

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Activated macrophages create lineage-specific microenvironments for pancreatic acinar- and β-cell regeneration in mice

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Low-dose 5-aza-2'-deoxycytidine pretreatment inhibits experimental autoimmune encephalomyelitis by induction of regulatory T cells

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A preliminary evaluation of efficacy and safety of Wharton's jelly mesenchymal stem cell transplantation in patients with type 2 diabetes mellitus.

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The M1 and M2 paradigm of macrophage activation: time for reassessment

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M2 macrophages promote beta-cell proliferation by up-regulation of SMAD7.

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Islet microenvironment, modulated by vascular endothelial growth factor-A signaling, promotes β cell regeneration

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Islet beta cell failure in type 2 diabetes

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Oral antihyperglycemic therapy for type 2 diabetes: scientific review

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11 February 2021

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10.1155/2020/4689798

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4 May 2020

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4 May 2020

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