LSH interacts with and stabilizes GINS4 transcript that promotes tumourigenesis in non-small cell lung cancer (Q93112025)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31253190 AND SRC:MED&resulttype=core&format=json

3 May 2020

title

LSH interacts with and stabilizes GINS4 transcript that promotes tumourigenesis in non-small cell lung cancer (English)

1 reference

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non-small-cell lung carcinoma

3 May 2020

main subject

1 reference

18

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3 May 2020

author name string

Rui Yang

1

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3 May 2020

Na Liu

2

1 reference

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3 May 2020

Ling Chen

3

1 reference

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3 May 2020

Yiqun Jiang

4

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3 May 2020

Ying Shi

5

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3 May 2020

Chao Mao

6

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3 May 2020

Yating Liu

7

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3 May 2020

Min Wang

8

1 reference

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3 May 2020

Weiwei Lai

9

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3 May 2020

Haosheng Tang

10

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3 May 2020

Menghui Gao

11

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3 May 2020

Desheng Xiao

12

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3 May 2020

Xiang Wang

13

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3 May 2020

Fenglei Yu

14

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3 May 2020

Ya Cao

15

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3 May 2020

Qin Yan

16

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3 May 2020

Shuang Liu

17

1 reference

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3 May 2020

publication date

28 June 2019

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Journal of Experimental & Clinical Cancer Research

3 May 2020

published in

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3 May 2020

volume

38

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3 May 2020

issue

1

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3 May 2020

page(s)

280

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SWI/SNF remains localized to chromatin in the presence of SCHLAP1

3 May 2020

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Modular Organization and Assembly of SWI/SNF Family Chromatin Remodeling Complexes

11 February 2021

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Aryl hydrocarbon receptor activated by benzo (a) pyrene promotes SMARCA6 expression in NSCLC

11 February 2021

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Activation of AhR with nuclear IKKα regulates cancer stem-like properties in the occurrence of radioresistance.

11 February 2021

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A G3BP1-interacting lncRNA promotes ferroptosis and apoptosis in cancer via nuclear sequestration of p53.

11 February 2021

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Nuclear EGFR-PKM2 axis induces cancer stem cell-like characteristics in irradiation-resistant cells.

11 February 2021

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Decrease in Lymphoid Specific Helicase and 5-hydroxymethylcytosine Is Associated with Metastasis and Genome Instability

11 February 2021

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EGLN1/c-Myc Induced Lymphoid-Specific Helicase Inhibits Ferroptosis through Lipid Metabolic Gene Expression Changes

11 February 2021

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Long Noncoding RNA and Cancer: A New Paradigm

11 February 2021

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Posttranscriptional Regulation of PARG mRNA by HuR Facilitates DNA Repair and Resistance to PARP Inhibitors.

11 February 2021

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Posttranscriptional Upregulation of IDH1 by HuR Establishes a Powerful Survival Phenotype in Pancreatic Cancer Cells.

11 February 2021

1 reference

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RNA Binding by Histone Methyltransferases Set1 and Set2.

11 February 2021

1 reference

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Mcm10 regulates DNA replication elongation by stimulating the CMG replicative helicase

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

KDM5 lysine demethylases are involved in maintenance of 3'UTR length.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

Chromatin Remodeling Factor LSH is Upregulated by the LRP6-GSK3β-E2F1 Axis Linking Reversely with Survival in Gliomas

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

Regulation of SLD5 gene expression by miR-370 during acute growth of cancer cells

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

Chromatin remodeling factor LSH affects fumarate hydratase as a cancer driver

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

Chromatin Remodeling Factor LSH Drives Cancer Progression by Suppressing the Activity of Fumarate Hydratase

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

Long Noncoding RNAs in Cancer Pathways

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

Epigenetic modulators, modifiers and mediators in cancer aetiology and progression

11 February 2021

1 reference

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Cancer statistics in China, 2015.

11 February 2021

1 reference

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The ratio of FoxA1 to FoxA2 in lung adenocarcinoma is regulated by LncRNA HOTAIR and chromatin remodeling factor LSH.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

Repression of Hox genes by LMP1 in nasopharyngeal carcinoma and modulation of glycolytic pathway genes by HoxC8.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

The ATP binding site of the chromatin remodeling homolog Lsh is required for nucleosome density and de novo DNA methylation at repeat sequences

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

DNA damage enhanced by the attenuation of SLD5 delays cell cycle restoration in normal cells but not in cancer cells

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

Genome-wide DNA methylation patterns in LSH mutant reveals de-repression of repeat elements and redundant epigenetic silencing pathways

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

Transcriptome sequencing reveals altered long intergenic non-coding RNAs in lung cancer

11 February 2021

1 reference

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CG hypomethylation in Lsh-/- mouse embryonic fibroblasts is associated with de novo H3K4me1 formation and altered cellular plasticity

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

New strategies in lung cancer: epigenetic therapy for non-small cell lung cancer

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

HuR posttranscriptionally regulates WEE1: implications for the DNA damage response in pancreatic cancer cells

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

Lsh regulates LTR retrotransposon repression independently of Dnmt3b function

11 February 2021

1 reference

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Management of non-small-cell lung cancer: recent developments

11 February 2021

1 reference

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The Arabidopsis nucleosome remodeler DDM1 allows DNA methyltransferases to access H1-containing heterochromatin

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

Long noncoding RNAs: cellular address codes in development and disease

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

The SNF2 family ATPase LSH promotes phosphorylation of H2AX and efficient repair of DNA double-strand breaks in mammalian cells

11 February 2021

1 reference

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Nuclear epidermal growth factor receptor interacts with transcriptional intermediary factor 2 to activate cyclin D1 gene expression triggered by the oncoprotein latent membrane protein 1.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

Cdc6 expression represses E-cadherin transcription and activates adjacent replication origins.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

The SNF2-like helicase HELLS mediates E2F3-dependent transcription and cellular transformation

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

Treatment of breast cancer cells with DNA demethylating agents leads to a release of Pol II stalling at genes with DNA-hypermethylated regions upstream of TSS

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

Lsh, chromatin remodeling family member, modulates genome-wide cytosine methylation patterns at nonrepeat sequences

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

ΔNp63α is an oncogene that targets chromatin remodeler Lsh to drive skin stem cell proliferation and tumorigenesis

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

LSH and G9a/GLP complex are required for developmentally programmed DNA methylation

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

Lsh mediated RNA polymerase II stalling at HoxC6 and HoxC8 involves DNA methylation

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

A key role for the GINS complex at DNA replication forks

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

Structure of the human GINS complex and its assembly and functional interface in replication initiation

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

Identification and characterization of mouse PSF1-binding protein, SLD5

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

Lsh-deficient murine embryonal fibroblasts show reduced proliferation with signs of abnormal mitosis

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6599244

10.1186/S13046-019-1276-Y

11 February 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31253190 AND SRC:MED&resulttype=core&format=json

3 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31253190 AND SRC:MED&resulttype=core&format=json

3 May 2020

PubMed publication ID

31253190

1 reference