Single-cell analysis reveals the KIT D816V mutation in haematopoietic stem and progenitor cells in systemic mastocytosis (Q93037900)

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3 May 2020

title

Single-cell analysis reveals the KIT D816V mutation in haematopoietic stem and progenitor cells in systemic mastocytosis (English)

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3 May 2020

main subject

systemic mastocytosis

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9

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3 May 2020

Gunnar Nilsson

10

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3 May 2020

Joakim S Dahlin

11

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3 May 2020

3

Maria Ekoff

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3 May 2020

1

Jennine Grootens

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3 May 2020

6

Rose-Marie Amini

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3 May 2020

2

Johanna S Ungerstedt

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3 May 2020

4

Elin Rönnberg

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3 May 2020

author name string

Monika Klimkowska

5

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3 May 2020

Michel Arock

7

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3 May 2020

Stina Söderlund

8

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3 May 2020

publication date

8 April 2019

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3 May 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30975542 AND SRC:MED&resulttype=core&format=json

3 May 2020

volume

43

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3 May 2020

page(s)

150-158

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Deciphering the differentiation trajectory from hematopoietic stem cells to mast cells

3 May 2020

cites work

1 reference

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Characterization of CD34 hematopoietic cells in systemic mastocytosis: potential role in disease dissemination.

11 February 2021

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KIT signaling is dispensable for human mast cell progenitor development

11 February 2021

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11 February 2021

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Detection of circulating mast cells in advanced systemic mastocytosis

11 February 2021

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11 February 2021

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Lin- CD34hi CD117int/hi FcεRI cells in human blood constitute a rare population of mast cell progenitors

11 February 2021

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Detection of the KIT D816V mutation in peripheral blood of systemic mastocytosis: diagnostic implications

11 February 2021

1 reference

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Mast cells in systemic mastocytosis have distinctly brighter CD45 expression by flow cytometry.

11 February 2021

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Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow

11 February 2021

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KIT mutation analysis in mast cell neoplasms: recommendations of the European Competence Network on Mastocytosis

11 February 2021

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Molecular profiling of myeloid progenitor cells in multi-mutated advanced systemic mastocytosis identifies KIT D816V as a distinct and late event.

11 February 2021

1 reference

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The immunophenotype of mast cells and its utility in the diagnostic work-up of systemic mastocytosis

11 February 2021

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CD52 is a molecular target in advanced systemic mastocytosis.

11 February 2021

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A new human mast cell line expressing a functional IgE receptor converts to tumorigenic growth by KIT D816V transfection

11 February 2021

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Mast cell progenitors: origin, development and migration to tissues

11 February 2021

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Revision of the human hematopoietic tree: granulocyte subtypes derive from distinct hematopoietic lineages.

11 February 2021

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Immunophenotyping in systemic mastocytosis diagnosis: 'CD25 positive' alone is more informative than the 'CD25 and/or CD2' WHO criterion.

11 February 2021

1 reference

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Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment

11 February 2021

1 reference

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Improved detection of the KIT D816V mutation in patients with systemic mastocytosis using a quantitative and highly sensitive real-time qPCR assay

11 February 2021

1 reference

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Coexistence of LMPP-like and GMP-like Leukemia Stem Cells in Acute Myeloid Leukemia

11 February 2021

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Aberrant expression of CD30 in neoplastic mast cells in high-grade mastocytosis

11 February 2021

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Revised map of the human progenitor hierarchy shows the origin of macrophages and dendritic cells in early lymphoid development

11 February 2021

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Mast cells from different molecular and prognostic subtypes of systemic mastocytosis display distinct immunophenotypes.

11 February 2021

1 reference

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Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood

11 February 2021

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Standards and standardization in mastocytosis: consensus statements on diagnostics, treatment recommendations and response criteria

11 February 2021

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KIT mutation in mast cells and other bone marrow hematopoietic cell lineages in systemic mast cell disorders: a prospective study of the Spanish Network on Mastocytosis (REMA) in a series of 113 patients

11 February 2021

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Analysis of the lineage relationship between mast cells and basophils using the c-kit D816V mutation as a biologic signature

11 February 2021

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11 February 2021

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Eosinophils are derived from the neoplastic clone in patients with systemic mastocytosis and eosinophilia

11 February 2021

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Functional and phenotypic studies of two variants of a human mast cell line with a distinct set of mutations in the c-kit proto-oncogene

11 February 2021

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11 February 2021

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Evidence for the involvement of a hematopoietic progenitor cell in systemic mastocytosis from single-cell analysis of mutations in the c-kit gene

11 February 2021

1 reference

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Multilineage involvement and erythropoietin-"independent" erythroid progenitor cells in a patient with systemic mastocytosis

11 February 2021

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Dendritic cell ontogeny: a human dendritic cell lineage of myeloid origin

11 February 2021

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Development of human mast cells from umbilical cord blood cells by recombinant human and murine c-kit ligand

11 February 2021

1 reference

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Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder

11 February 2021

1 reference

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Immunoperoxidase and enzyme-histochemical demonstration of human skin tryptase in cutaneous mast cells in normal and mastocytoma skin

11 February 2021

1 reference

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Induction of differentiation of human mast cells from bone marrow and peripheral blood mononuclear cells by recombinant human stem cell factor/kit-ligand in long-term culture

11 February 2021

1 reference

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Effect of IL-3 and stem cell factor on the appearance of human basophils and mast cells from CD34 pluripotent progenitor cells

11 February 2021

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Recombinant human stem cell factor stimulates differentiation of mast cells from dispersed human fetal liver cells

11 February 2021

1 reference

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10.1016/J.EBIOM.2019.03.089

11 February 2021

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30975542 AND SRC:MED&resulttype=core&format=json

3 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30975542 AND SRC:MED&resulttype=core&format=json

3 May 2020

PubMed publication ID

30975542

1 reference