Rationale and Roadmap for Developing Panels of Hotspot Cancer Driver Gene Mutations as Biomarkers of Cancer Risk (Q93009792)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31469467 AND SRC:MED&resulttype=core&format=json

3 May 2020

review article

1 reference

title

Rationale and Roadmap for Developing Panels of Hotspot Cancer Driver Gene Mutations as Biomarkers of Cancer Risk (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31469467 AND SRC:MED&resulttype=core&format=json

3 May 2020

1 reference

Kelly L Harris

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31469467 AND SRC:MED&resulttype=core&format=json

3 May 2020

Meagan B Myers

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31469467 AND SRC:MED&resulttype=core&format=json

3 May 2020

Karen L McKim

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31469467 AND SRC:MED&resulttype=core&format=json

3 May 2020

Rosalie K Elespuru

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31469467 AND SRC:MED&resulttype=core&format=json

3 May 2020

Barbara L Parsons

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31469467 AND SRC:MED&resulttype=core&format=json

3 May 2020

publication date

6 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31469467 AND SRC:MED&resulttype=core&format=json

Environmental and Molecular Mutagenesis

3 May 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31469467 AND SRC:MED&resulttype=core&format=json

3 May 2020

volume

61

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31469467 AND SRC:MED&resulttype=core&format=json

3 May 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31469467 AND SRC:MED&resulttype=core&format=json

3 May 2020

page(s)

152-175

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31469467 AND SRC:MED&resulttype=core&format=json

Ultra-Sensitive TP53 Sequencing for Cancer Detection Reveals Progressive Clonal Selection in Normal Tissue over a Century of Human Lifespan

3 May 2020

cites work

1 reference

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Passenger hotspot mutations in cancer driven by APOBEC3A and mesoscale genomic features

11 February 2021

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Regulatory assessment and risk management of chemical mixtures: challenges and ways forward

11 February 2021

1 reference

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Accumulation of genetic and epigenetic alterations in normal cells and cancer risk

11 February 2021

1 reference

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Low-Frequency Mutational Heterogeneity of Invasive Ductal Carcinoma Subtypes: Information to Direct Precision Oncology

11 February 2021

1 reference

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Toward liquid biopsies in cancer treatment: application of circulating tumor DNA

11 February 2021

1 reference

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Elevated expression of GNAS promotes breast cancer cell proliferation and migration via the PI3K/AKT/Snail1/E-cadherin axis

11 February 2021

1 reference

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Vascular-endothelial response to IDH1 mutant fibrosarcoma secretome and metabolite: implications on cancer microenvironment

11 February 2021

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11 February 2021

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Hormone signaling via androgen receptor affects breast cancer and prostate cancer in a male patient: A case report

11 February 2021

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ATM-Mediated Phosphorylation of Cortactin Involved in Actin Polymerization Promotes Breast Cancer Cells Migration and Invasion

11 February 2021

1 reference

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Steroidogenic differentiation and PKA signaling are programmed by histone methyltransferase EZH2 in the adrenal cortex.

11 February 2021

1 reference

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Osimertinib in patients with T790M mutation-positive, advanced non-small cell lung cancer: Long-term follow-up from a pooled analysis of 2 phase 2 studies

11 February 2021

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Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017

11 February 2021

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The expression profile of integrin receptors and osteopontin in thyroid malignancies varies depending on the tumor progression rate and presence of BRAF V600E mutation

11 February 2021

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TGF-β1 promotes gap junctions formation in chondrocytes via Smad3/Smad4 signalling

11 February 2021

1 reference

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Autocrine-paracrine prostaglandin E signaling restricts TLR4 internalization and TRIF signaling

11 February 2021

1 reference

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Quantitative Approaches to Assess Key Carcinogenic Events of Genotoxic Carcinogens

11 February 2021

1 reference

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Low Prevalence of TERT Promoter, BRAF and RAS Mutations in Papillary Thyroid Cancer in the Greek Population

11 February 2021

1 reference

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Somatic mutant clones colonize the human esophagus with age

11 February 2021

1 reference

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The COSMIC Cancer Gene Census: describing genetic dysfunction across all human cancers

11 February 2021

1 reference

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IL-17A Attenuates IFN-λ Expression by Inducing Suppressor of Cytokine Signaling Expression in Airway Epithelium

11 February 2021

1 reference

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Epidermal Growth Factor (EGF) Autocrine Activation of Human Platelets Promotes EGF Receptor-Dependent Oral Squamous Cell Carcinoma Invasion, Migration, and Epithelial Mesenchymal Transition

11 February 2021

1 reference

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Multiclonal tumor origin: Evidence and implications

11 February 2021

1 reference

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Clonal Expansion and Diversification of Cancer-Associated Mutations in Endometriosis and Normal Endometrium

11 February 2021

1 reference

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Validation of the Oncomine focus panel for next-generation sequencing of clinical tumour samples

11 February 2021

1 reference

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Regulation of Pituitary Progenitor Differentiation by β-Catenin

11 February 2021

1 reference

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Mouse ER /PIK3CAH1047R breast cancers caused by exogenous estrogen are heterogeneously dependent on estrogen and undergo BIM-dependent apoptosis with BH3 and PI3K agents.

11 February 2021

1 reference

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Inhibiting RHOA Signaling in Mice Increases Glucose Tolerance and Numbers of Enteroendocrine and Other Secretory Cells in the Intestine

11 February 2021

1 reference

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Cancer-mutation network and the number and specificity of driver mutations

11 February 2021

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Conditional Deletion of FOXL2 and SMAD4 in Gonadotropes of Adult Mice Causes Isolated FSH Deficiency

11 February 2021

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Silencing Stem Cell Factor Gene in Fibroblasts to Regulate Paracrine Factor Productions and Enhance c-Kit Expression in Melanocytes on Melanogenesis.

11 February 2021

1 reference

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Insulin signaling acts in adult adipocytes via GSK-3β and independently of FOXO to control Drosophila female germline stem cell numbers

11 February 2021

1 reference

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Comprehensive Characterization of Cancer Driver Genes and Mutations.

11 February 2021

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ER-positive breast cancer cells are poised for RET-mediated endocrine resistance.

11 February 2021

1 reference

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Cancer Genome Interpreter annotates the biological and clinical relevance of tumor alterations.

11 February 2021

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Enhancing the accuracy of next-generation sequencing for detecting rare and subclonal mutations.

11 February 2021

1 reference

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The crosstalk between breast carcinoma-associated fibroblasts and cancer cells promotes RhoA-dependent invasion via IGF-1 and PAI-1.

11 February 2021

1 reference

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Development and validation of a high-throughput transcriptomic biomarker to address 21st century genetic toxicology needs

11 February 2021

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ATM is required for the prolactin-induced HSP90-mediated increase in cellular viability and clonogenic growth after DNA damage

11 February 2021

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Cisplatin triggers cancer stem cell enrichment in platinum-resistant cells through NF-κB-TNFα-PIK3CA loop.

11 February 2021

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SBCDDB: Sleeping Beauty Cancer Driver Database for gene discovery in mouse models of human cancers

11 February 2021

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Photodynamic therapy inhibits melanogenesis through paracrine effects by keratinocytes and fibroblasts.

11 February 2021

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Applying 'omics technologies in chemicals risk assessment: Report of an ECETOC workshop.

11 February 2021

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Gonadotropin-Dependent Neuregulin-1 Signaling Regulates Female Rat Ovarian Granulosa Cell Survival

11 February 2021

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Moving forward in carcinogenicity assessment: Report of an EURL ECVAM/ESTIV workshop

11 February 2021

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Variation in organ-specific PIK3CA and KRAS mutant levels in normal human tissues correlates with mutation prevalence in corresponding carcinomas.

11 February 2021

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Mutations in Cancer Cause Gain of Cysteine, Histidine, and Tryptophan at the Expense of a Net Loss of Arginine on the Proteome Level

11 February 2021

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Bisphenol A activates EGFR and ERK promoting proliferation, tumor spheroid formation and resistance to EGFR pathway inhibition in estrogen receptor-negative inflammatory breast cancer cells

11 February 2021

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Exosome-delivered EGFR regulates liver microenvironment to promote gastric cancer liver metastasis

11 February 2021

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Acquired RAS or EGFR mutations and duration of response to EGFR blockade in colorectal cancer.

11 February 2021

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Evaluating the evaluation of cancer driver genes

11 February 2021

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KRAS mutant tumor subpopulations can subvert durable responses to personalized cancer treatments

11 February 2021

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Spatial Rho regulation: Molecular mechanisms controlling the GAP protein DLC3.

11 February 2021

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Low-frequency KRAS mutations are prevalent in lung adenocarcinomas

11 February 2021

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Enhancer of Zeste Homolog 2 Inhibition Stimulates Bone Formation and Mitigates Bone Loss Caused by Ovariectomy in Skeletally Mature Mice

11 February 2021

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Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults

11 February 2021

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Low-Dose Mixture Hypothesis of Carcinogenesis Workshop: Scientific Underpinnings and Research Recommendations

11 February 2021

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Biomarkers of genome instability and cancer epigenetics.

11 February 2021

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KRASG12 mutant induces the release of the WSTF/NRG3 complex, and contributes to an oncogenic paracrine signaling pathway

11 February 2021

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AKT Signaling Prevailing in Mesenchymal Stromal Cells Modulates the Functionality of Hematopoietic Stem Cells via Intercellular Communication

11 February 2021

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Current practices and guidelines for clinical next-generation sequencing oncology testing

11 February 2021

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KRAS-MEK Signaling Controls Ago2 Sorting into Exosomes

11 February 2021

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Breast Cancer Heterogeneity Examined by High-Sensitivity Quantification of PIK3CA, KRAS, HRAS, and BRAF Mutations in Normal Breast and Ductal Carcinomas

11 February 2021

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Association of polymorphisms in the MyD88, IRAK4 and TRAF6 genes and susceptibility to type 2 diabetes mellitus and diabetic nephropathy in a southern Han Chinese population

11 February 2021

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Autotaxin Regulates Maintenance of Ovarian Cancer Stem Cells through Lysophosphatidic Acid-Mediated Autocrine Mechanism.

11 February 2021

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Key Characteristics of Carcinogens as a Basis for Organizing Data on Mechanisms of Carcinogenesis

11 February 2021

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Targeted single molecule mutation detection with massively parallel sequencing

11 February 2021

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Mutation tracking in circulating tumor DNA predicts relapse in early breast cancer

11 February 2021

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MacroH2A1 and ATM Play Opposing Roles in Paracrine Senescence and the Senescence-Associated Secretory Phenotype

11 February 2021

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The scientific basis of uncertainty factors used in setting occupational exposure limits

11 February 2021

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Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients.

11 February 2021

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TP53: an oncogene in disguise.

11 February 2021

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Disruption of Smad4 in odontoblasts and dental epithelial cells influences the phenotype of multiple keratocystic odontogenic tumors.

11 February 2021

1 reference

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Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin

11 February 2021

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IWGT report on quantitative approaches to genotoxicity risk assessment II. Use of point-of-departure (PoD) metrics in defining acceptable exposure limits and assessing human risk.

11 February 2021

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Activating PIK3CA Mutations Induce an Epidermal Growth Factor Receptor (EGFR)/Extracellular Signal-regulated Kinase (ERK) Paracrine Signaling Axis in Basal-like Breast Cancer

11 February 2021

1 reference

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Loss of TGFβ Receptor Type 2 Expression Impairs Estrogen Response and Confers Tamoxifen Resistance

11 February 2021

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Quantifying ultra-rare pre-leukemic clones via targeted error-corrected sequencing

11 February 2021

1 reference

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Regulatory Forum Opinion Piece*: Transgenic/Alternative Carcinogenicity Assays: A Retrospective Review of Studies Submitted to CDER/FDA 1997-2014.

11 February 2021

1 reference

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Paracrine regulation of glioma cells invasion by astrocytes is mediated by glial-derived neurotrophic factor

11 February 2021

1 reference

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Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia.

11 February 2021

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Stromal Indian hedgehog signaling is required for intestinal adenoma formation in mice

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Menin determines K-RAS proliferative outputs in endocrine cells

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Induction of the matricellular protein CCN1 through RhoA and MRTF-A contributes to ischemic cardioprotection.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Loss of Fbw7 reprograms adult pancreatic ductal cells into α, δ, and β cells

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Direct transcriptional repression of Zfp423 by Zfp521 mediates a bone morphogenic protein-dependent osteoblast versus adipocyte lineage commitment switch

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Biologic and clinical significance of androgen receptor variants in castration resistant prostate cancer

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

SDS, a structural disruption score for assessment of missense variant deleteriousness.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Mode of action human relevance (species concordance) framework: Evolution of the Bradford Hill considerations and comparative analysis of weight of evidence

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

p53 inactivation decreases dependence on estrogen/ERK signalling for proliferation but promotes EMT and susceptility to 3-bromopyruvate in ERα breast cancer MCF-7 cells.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Mutational landscape and significance across 12 major cancer types

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Dysregulated STAT1-SOCS1 control of JAK2 promotes mammary luminal progenitor cell survival and drives ERα( ) tumorigenesis

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

The canonical WNT2 pathway and FSH interact to regulate gap junction assembly in mouse granulosa cells

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Transformation of epithelial cells through recruitment leads to polyclonal intestinal tumors

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Accurately identifying low-allelic fraction variants in single samples with next-generation sequencing: applications in tumor subclone resolution

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Long-term fasting in the anadromous Arctic charr is associated with downregulation of metabolic enzyme activity and upregulation of leptin A1 and SOCS expression in the liver

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Personalized cancer treatment and the myth of KRAS wild-type colon tumors

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Growth of triple-negative breast cancer cells relies upon coordinate autocrine expression of the proinflammatory cytokines IL-6 and IL-8.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

11 February 2021

Cancer genome landscapes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

A subset of papillary thyroid carcinomas contain KRAS mutant subpopulations at levels above normal thyroid

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

IL-1R-MyD88 signaling in keratinocyte transformation and carcinogenesis

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

The Origin and Evolution of Mutations in Acute Myeloid Leukemia

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Epidermal growth factor regulates connexin 43 in the human epididymis: role of gap junctions in azoospermia

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Intra-tumour heterogeneity: a looking glass for cancer?

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Transcriptomic fingerprints in human peripheral blood mononuclear cells indicative of genotoxic and non-genotoxic carcinogenic exposure

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

CTNNB1 signaling in sertoli cells downregulates spermatogonial stem cell activity via WNT4

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Induction of vascular endothelial growth factor secretion by childhood acute lymphoblastic leukemia cells via the FLT-3 signaling pathway.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Arginine residues at internal positions in a protein are always charged

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Signal transducer and activator of transcription-6 (STAT6) inhibition suppresses renal cyst growth in polycystic kidney disease.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Field cancerization in the GI tract.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Substitution rate variation at human CpG sites correlates with non-CpG divergence, methylation level and GC content

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

An analysis of pharmaceutical experience with decades of rat carcinogenicity testing: support for a proposal to modify current regulatory guidelines.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Detection and quantification of rare mutations with massively parallel sequencing

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Evaluation of carcinogenicity studies of medicinal products for human use authorised via the European centralised procedure (1995–2009)

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

A Critical Review of the Effectiveness of Rodent Pharmaceutical Carcinogenesis Testing in Predicting for Human Risk

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Hallmarks of Cancer: The Next Generation

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Morphological and functional alterations in adult boar epididymis: Effects of prenatal and postnatal administration of flutamide

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Effects of androgen receptor and androgen on gene expression in prostate stromal fibroblasts and paracrine signaling to prostate cancer cells

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Epiregulin-dependent amphiregulin expression and ERBB2 signaling are involved in luteinizing hormone-induced paracrine signaling pathways in mouse ovary

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Multiple oncogenic mutations and clonal relationship in spatially distinct benign human epidermal tumors

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

ACB-PCR quantification of K-RAS codon 12 GAT and GTT mutant fraction in colon tumor and non-tumor tissue.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Finding transcriptomics biomarkers for in vivo identification of (non-)genotoxic carcinogens using wild-type and Xpa/p53 mutant mouse models

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Autocrine regulation of early embryonic development by the artemin-GFRA3 (GDNF family receptor-alpha 3) signaling system in mice.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Urothelial transdifferentiation to prostate epithelia is mediated by paracrine TGF-beta signaling.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Pathophysiological aspects of Wnt-signaling in endocrine disease

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Analysis of p53 mutations in histologically normal lung tissues and lung tumors from non-small cell lung cancer patients

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Many different tumor types have polyclonal tumor origin: evidence and implications.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Akt1 governs breast cancer progression in vivo

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Smad4-dependent regulation of urokinase plasminogen activator secretion and RNA stability associated with invasiveness by autocrine and paracrine transforming growth factor-beta

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Distributions of five common point mutants in the human tracheal-bronchial epithelium

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Evolution of intratumoral genetic heterogeneity during colorectal cancer progression.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Development of an autocrine neuregulin signaling loop with malignant transformation of human breast epithelial cells

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Overexpression of collagenase 1 (MMP-1) is mediated by the ERK pathway in invasive melanoma cells: role of BRAF mutation and fibroblast growth factor signaling

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

FLT3 ligand causes autocrine signaling in acute myeloid leukemia cells

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Cells heterozygous for the ApcMin mutation have decreased gap junctional intercellular communication and connexin43 level, and reduced microtubule polymerization.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

The use of non-tumor data in cancer risk assessment: reflections on butadiene, vinyl chloride, and benzene

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

BCL2 expression correlates with metastatic potential in pancreatic cancer cell lines.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

C-erbB2/neu transfection induces gap junctional communication incompetence in glial cells.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Characterization of ret oncogenic activation in MEN2 inherited cancer syndromes

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

N-nitroso-N-methylurea-induced rat mammary tumors arise from cells with preexisting oncogenic Hras1 gene mutations

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

Clonal analysis of human colorectal tumors

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

The clonal evolution of tumor cell populations

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6973253

11 February 2021

Identifiers

DOI

10.1002/EM.22326

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31469467 AND SRC:MED&resulttype=core&format=json

3 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31469467 AND SRC:MED&resulttype=core&format=json

3 May 2020

PubMed publication ID

31469467

1 reference