Competitive Binding of Magnesium to Calcium Binding Sites Reciprocally Regulates Transamidase and GTP Hydrolysis Activity of Transglutaminase 2 (Q93006482)

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scientific article published on 25 January 2020

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English	Competitive Binding of Magnesium to Calcium Binding Sites Reciprocally Regulates Transamidase and GTP Hydrolysis Activity of Transglutaminase 2	scientific article published on 25 January 2020

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scholarly article

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3 May 2020

Competitive Binding of Magnesium to Calcium Binding Sites Reciprocally Regulates Transamidase and GTP Hydrolysis Activity of Transglutaminase 2 (English)

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3 May 2020

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3 May 2020

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Ki Baek Lee

2

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3 May 2020

Gi Eob Kim

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3 May 2020

Chang Min Kim

4

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3 May 2020

Jin-Haeng Lee

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Hyo-Jun Kim

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3 May 2020

Ji-Woong Shin

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3 May 2020

Mee-Ae Kwon

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3 May 2020

Hyun Ho Park

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3 May 2020

In-Gyu Kim

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25 January 2020

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3 May 2020

International Journal of Molecular Sciences

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3 May 2020

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3 May 2020

3

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3 May 2020

copyright license

Creative Commons Attribution 4.0 International

25 January 2020

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Structure of natural variant transglutaminase 2 reveals molecular basis of gaining stability and higher activity

1 reference

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Transglutaminase 2 mediates UV-induced skin inflammation by enhancing inflammatory cytokine production.

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Processing of X-ray diffraction data collected in oscillation mode

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Transglutaminase 2 has opposing roles in the regulation of cellular functions as well as cell growth and death

1 reference

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Invited review: Activation of G proteins by GTP and the mechanism of Gα-catalyzed GTP hydrolysis

1 reference

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11 February 2021

Association between magnesium intake and risk of colorectal cancer among postmenopausal women.

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11 February 2021

Crystal structure of transglutaminase 2 with GTP complex and amino acid sequence evidence of evolution of GTP binding site

1 reference

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11 February 2021

Crystallization and preliminary X-ray crystallographic studies of transglutaminase 2 in complex with Ca2 .

1 reference

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11 February 2021

Magnesium intake is inversely associated with coronary artery calcification: the Framingham Heart Study

1 reference

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Structure of active coagulation factor XIII triggered by calcium binding: basis for the design of next-generation anticoagulants

1 reference

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11 February 2021

The role of magnesium for geometry and charge in GTP hydrolysis, revealed by quantum mechanics/molecular mechanics simulations

1 reference

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11 February 2021

Magnesium decreases inflammatory cytokine production: a novel innate immunomodulatory mechanism

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Doxorubicin induces the persistent activation of intracellular transglutaminase 2 that protects from cell death

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Epithelial transglutaminase 2 is needed for T cell interleukin-17 production and subsequent pulmonary inflammation and fibrosis in bleomycin-treated mice

1 reference

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11 February 2021

On the roles of Mg in the activation of G proteins

1 reference

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11 February 2021

Magnesium homeostasis and aging

1 reference

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MolProbity: all-atom structure validation for macromolecular crystallography

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11 February 2021

Functional significance of five noncanonical Ca2 -binding sites of human transglutaminase 2 characterized by site-directed mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7037829

11 February 2021

Transglutaminase 2 suppresses apoptosis by modulating caspase 3 and NF-kappaB activity in hypoxic tumor cells

1 reference

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11 February 2021

Transglutaminases and disease: lessons from genetically engineered mouse models and inherited disorders.

1 reference

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11 February 2021

Degradation of transglutaminase 2 by calcium-mediated ubiquitination responding to high oxidative stress

1 reference

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Magnesium deficiency accelerates cellular senescence in cultured human fibroblasts

1 reference

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11 February 2021

Transglutaminase 2 undergoes a large conformational change upon activation

1 reference

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Calcium signaling

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Magnesium homeostasis in mammalian cells.

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Mutation of a critical arginine in the GTP-binding site of transglutaminase 2 disinhibits intracellular cross-linking activity

1 reference

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Magnesium intake in relation to risk of colorectal cancer in women

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1 reference

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1 reference

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1 reference

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GTP modulates calcium binding and cation-induced conformational changes in erythrocyte transglutaminase

1 reference

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11 February 2021

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10.3390/IJMS21030791

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3 May 2020

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3 May 2020

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3 May 2020

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