Prion protein quantification in human cerebrospinal fluid as a tool for prion disease drug development (Q92766222)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30936307 AND SRC:MED&resulttype=core&format=json

1 May 2020

title

Prion protein quantification in human cerebrospinal fluid as a tool for prion disease drug development (English)

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1 May 2020

4

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1 May 2020

Piero Parchi

5

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1 May 2020

Kathryn J Swoboda

11

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1 May 2020

Eric Minikel

15

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13

Henrik Zetterberg

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1 May 2020

12

Michael D Geschwind

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1 May 2020

16

Stuart L Schreiber

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1 May 2020

author name string

Sonia M Vallabh

1

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1 May 2020

Chloe K Nobuhara

2

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1 May 2020

Franc Llorens

3

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1 May 2020

Sabina Capellari

6

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1 May 2020

Eric Kuhn

7

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1 May 2020

Jacob Klickstein

8

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1 May 2020

Jiri G Safar

9

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Flavia C Nery

10

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1 May 2020

Steven E Arnold

14

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1 May 2020

publication date

1 April 2019

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Proceedings of the National Academy of Sciences of the United States of America

1 May 2020

published in

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1 May 2020

volume

116

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1 May 2020

issue

16

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1 May 2020

page(s)

7793-7798

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Structural and mechanistic aspects influencing the ADAM10-mediated shedding of the prion protein.

1 May 2020

cites work

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RT-QuIC Assays for Prion Disease Detection and Diagnostics

11 February 2021

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Effects of the Insulin Sensitizer Metformin in Alzheimer Disease: Pilot Data From a Randomized Placebo-controlled Crossover Study

11 February 2021

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Genetic prion disease: Experience of a rapidly progressive dementia center in the United States and a review of the literature.

11 February 2021

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Diagnostic and prognostic value of human prion detection in cerebrospinal fluid

11 February 2021

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Diagnostic Accuracy of a Combined Analysis of Cerebrospinal Fluid t-PrP, t-tau, p-tau, and Aβ42 in the Differential Diagnosis of Creutzfeldt-Jakob Disease from Alzheimer's Disease with Emphasis on Atypical Disease Variants

11 February 2021

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Quantifying prion disease penetrance using large population control cohorts

11 February 2021

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Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patients

11 February 2021

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Association of cerebrospinal fluid prion protein levels and the distinction between Alzheimer disease and Creutzfeldt-Jakob disease

11 February 2021

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Convection-enhanced delivery of AAV2-PrPshRNA in prion-infected mice

11 February 2021

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Effects of blood contamination and the rostro-caudal gradient on the human cerebrospinal fluid proteome

11 February 2021

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Novel compounds lowering the cellular isoform of the human prion protein in cultured human cells

11 February 2021

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Prion disease tempo determined by host-dependent substrate reduction

11 February 2021

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Doxycycline in Creutzfeldt-Jakob disease: a phase 2, randomised, double-blind, placebo-controlled trial.

11 February 2021

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Quinacrine treatment trial for sporadic Creutzfeldt-Jakob disease

11 February 2021

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PrP mRNA and protein expression in brain and PrP(c) in CSF in Creutzfeldt-Jakob disease MM1 and VV2.

11 February 2021

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An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study

11 February 2021

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Intracerebral Infusion of Antisense Oligonucleotides Into Prion-infected Mice

11 February 2021

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Healthy goats naturally devoid of prion protein

11 February 2021

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Real time quaking-induced conversion analysis of cerebrospinal fluid in sporadic Creutzfeldt-Jakob disease

11 February 2021

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Altered Prion protein expression pattern in CSF as a biomarker for Creutzfeldt-Jakob disease

11 February 2021

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Risk of Alzheimer's Disease Biological Misdiagnosis Linked to Cerebrospinal Collection Tubes

11 February 2021

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Ultrasensitive human prion detection in cerebrospinal fluid by real-time quaking-induced conversion.

11 February 2021

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Rapid End-Point Quantitation of Prion Seeding Activity with Sensitivity Comparable to Bioassays

11 February 2021

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Codon 129 polymorphism and the E200K mutation do not affect the cellular prion protein isoform composition in the cerebrospinal fluid from patients with Creutzfeldt-Jakob disease

11 February 2021

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Axonal prion protein is required for peripheral myelin maintenance

11 February 2021

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Total prion protein levels in the cerebrospinal fluid are reduced in patients with various neurological disorders

11 February 2021

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Generation of goats lacking prion protein

11 February 2021

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Single treatment with RNAi against prion protein rescues early neuronal dysfunction and prolongs survival in mice with prion disease

11 February 2021

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Production of cattle lacking prion protein.

11 February 2021

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Effect of Sample Collection Tubes on Cerebrospinal Fluid Concentrations of Tau Proteins and Amyloid Peptides

11 February 2021

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11 February 2021

Prion disease genetics

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Prion clearance in bigenic mice

11 February 2021

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The impact of blood contamination on the proteome of cerebrospinal fluid

11 February 2021

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11 February 2021

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Protein measurement with the Folin phenol reagent

11 February 2021

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Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis.

11 February 2021

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Proteins in cerebrospinal fluid and blood: barriers, CSF flow rate and source-related dynamics

11 February 2021

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Distribution of cell-associated prion protein in normal adult blood determined by flow cytometry

11 February 2021

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Application of a time-resolved fluoroimmunoassay for the analysis of normal prion protein in human blood and its components

11 February 2021

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Classification of sporadic Creutzfeldt-Jakob disease based on molecular and phenotypic analysis of 300 subjects

11 February 2021

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11 February 2021

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Liposome solubilization and membrane protein reconstitution using Chaps and Chapso

11 February 2021

1 reference

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High prion and PrPSc levels but delayed onset of disease in scrapie-inoculated mice heterozygous for a disrupted PrP gene

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6475435

Control of aggregation in protein refolding: a variety of surfactants promote renaturation of carbonic anhydrase II.

11 February 2021

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Mice devoid of PrP are resistant to scrapie

11 February 2021

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6475435

16 Solubilization of functional membrane proteins

11 February 2021

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6475435

N-terminal truncation of the scrapie-associated form of PrP by lysosomal protease(s): implications regarding the site of conversion of PrP to the protease-resistant state

11 February 2021

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6475435

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

11 February 2021

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6475435

11 February 2021

Identifiers

DOI

10.1073/PNAS.1901947116

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30936307 AND SRC:MED&resulttype=core&format=json

1 May 2020

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1 May 2020

PubMed publication ID

30936307

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