β-Catenin Activation Promotes Immune Escape and Resistance to Anti-PD-1 Therapy in Hepatocellular Carcinoma (Q92665666)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

title

β-Catenin Activation Promotes Immune Escape and Resistance to Anti-PD-1 Therapy in Hepatocellular Carcinoma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

evasion of host immune response

1 May 2020

main subject

1 reference

based on heuristic

inferred from title

hepatocellular carcinoma

1 reference

based on heuristic

inferred from title

author

Marina Ruiz de Galarreta

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

Marc Puigvehí

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

María Casanova-Acebes

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

Maxime Dhainaut

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

Johann von Felden

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

Alice O Kamphorst

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

Josep M. Llovet

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

Amaia Lujambio

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

22

Miriam Merad

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

author name string

Erin Bresnahan

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

Pedro Molina-Sánchez

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

Katherine E Lindblad

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

Barbara Maier

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

Daniela Sia

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

Verónica Miguela

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

Carlos Villacorta-Martin

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

Aatur D Singhi

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

Akshata Moghe

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

Lauren Tal Grinspan

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

Shuang Wang

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

Satdarshan P Monga

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

Brian D Brown

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

Augusto Villanueva

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

publication date

11 June 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

page(s)

1124-1141

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

Systemic clinical tumor regressions and potentiation of PD1 blockade with in situ vaccination

1 May 2020

cites work

1 reference

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WNT/β-catenin Pathway Activation Correlates with Immune Exclusion across Human Cancers

11 February 2021

1 reference

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Immune Exclusion-Wnt/CTNNB1 Class Predicts Resistance to Immunotherapies in HCC

11 February 2021

1 reference

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Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade.

11 February 2021

1 reference

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A novel spontaneous hepatocellular carcinoma mouse model for studying T-cell exhaustion in the tumor microenvironment

11 February 2021

1 reference

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Low and variable tumor reactivity of the intratumoral TCR repertoire in human cancers

11 February 2021

1 reference

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Prospective Genotyping of Hepatocellular Carcinoma: Clinical Implications of Next Generation Sequencing for Matching Patients to Targeted and Immune Therapies

11 February 2021

1 reference

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Molecular therapies and precision medicine for hepatocellular carcinoma

11 February 2021

1 reference

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Cabozantinib in Patients with Advanced and Progressing Hepatocellular Carcinoma

11 February 2021

1 reference

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Mouse models of hepatocellular carcinoma: an overview and highlights for immunotherapy research

11 February 2021

1 reference

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Pembrolizumab in patients with advanced hepatocellular carcinoma previously treated with sorafenib (KEYNOTE-224): a non-randomised, open-label phase 2 trial

11 February 2021

1 reference

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Bystander CD8 T cells are abundant and phenotypically distinct in human tumour infiltrates

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6677618

ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade

11 February 2021

1 reference

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EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma

11 February 2021

1 reference

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Lenvatinib versus sorafenib in first-line treatment of patients with unresectable hepatocellular carcinoma: a randomised phase 3 non-inferiority trial

11 February 2021

1 reference

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Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma

11 February 2021

1 reference

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A major chromatin regulator determines resistance of tumor cells to T cell-mediated killing

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6677618

Identification of an Immune-specific Class of Hepatocellular Carcinoma, Based on Molecular Features

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6677618

Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6677618

Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6677618

Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6677618

Combination immunotherapy: a road map.

11 February 2021

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Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6677618

Regorafenib for patients with hepatocellular carcinoma who progressed on sorafenib treatment (RESORCE): a randomised, double-blind, placebo-controlled, phase 3 trial

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6677618

The Role of Liver Biopsy in Hepatocellular Carcinoma

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6677618

Palbociclib (PD-0332991), a selective CDK4/6 inhibitor, restricts tumour growth in preclinical models of hepatocellular carcinoma.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6677618

Mouse models in oncoimmunology

11 February 2021

1 reference

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Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma

11 February 2021

1 reference

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Expansion and Activation of CD103( ) Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition.

11 February 2021

1 reference

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Comprehensive multiplatform biomarker analysis of 350 hepatocellular carcinomas identifies potential novel therapeutic options

11 February 2021

1 reference

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Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy.

11 February 2021

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Immunological landscape and immunotherapy of hepatocellular carcinoma

11 February 2021

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PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

11 February 2021

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Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma

11 February 2021

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Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity

11 February 2021

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Pembrolizumab for the treatment of non-small-cell lung cancer

11 February 2021

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Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets

11 February 2021

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Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

11 February 2021

1 reference

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Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

11 February 2021

1 reference

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Genetic basis for clinical response to CTLA-4 blockade in melanoma

11 February 2021

1 reference

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CRISPR-mediated direct mutation of cancer genes in the mouse liver

11 February 2021

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Hydrodynamic transfection for generation of novel mouse models for liver cancer research

11 February 2021

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featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

11 February 2021

1 reference

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Durable cancer regression off-treatment and effective reinduction therapy with an anti-PD-1 antibody

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6677618

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

11 February 2021

1 reference

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Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

11 February 2021

1 reference

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The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

11 February 2021

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Expression of tumour-specific antigens underlies cancer immunoediting

11 February 2021

1 reference

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11 February 2021

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Endogenous T Cell Responses to Antigens Expressed in Lung Adenocarcinomas Delay Malignant Tumor Progression

11 February 2021

1 reference

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Modified RECIST (mRECIST) assessment for hepatocellular carcinoma

11 February 2021

1 reference

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Identification of the murine firefly luciferase-specific CD8 T-cell epitopes.

11 February 2021

1 reference

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Batf3 Deficiency Reveals a Critical Role for CD8 Dendritic Cells in Cytotoxic T Cell Immunity

11 February 2021

1 reference

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Focal gains of VEGFA and molecular classification of hepatocellular carcinoma

11 February 2021

1 reference

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Sorafenib in advanced hepatocellular carcinoma

11 February 2021

1 reference

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Distinct pathways of genomic progression to benign and malignant tumors of the liver.

11 February 2021

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Maximizing mouse cancer models

11 February 2021

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CCL5-enhanced human immature dendritic cell migration through the basement membrane in vitro depends on matrix metalloproteinase-9.

11 February 2021

1 reference

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

11 February 2021

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Androgen ablation mitigates tolerance to a prostate/prostate cancer-restricted antigen

11 February 2021

1 reference

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Bystander elimination of antigen loss variants in established tumors

11 February 2021

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Cancer immunoediting: from immunosurveillance to tumor escape

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6677618

Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction

11 February 2021

1 reference

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10.1158/2159-8290.CD-19-0074

11 February 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31186238 AND SRC:MED&resulttype=core&format=json

1 May 2020

PubMed publication ID

31186238

1 reference