Comprehensive single cell mRNA profiling reveals a detailed roadmap for pancreatic endocrinogenesis (Q92500947)

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30 April 2020

title

Comprehensive single cell mRNA profiling reveals a detailed roadmap for pancreatic endocrinogenesis (English)

1 reference

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single cell transcriptomics

30 April 2020

main subject

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author

Sophie Tritschler

2

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30 April 2020

Leander Dony

3

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30 April 2020

Fabian J. Theis

10

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30 April 2020

Heiko Lickert

11

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30 April 2020

Mostafa Bakhti

12

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30 April 2020

author name string

Aimée Bastidas-Ponce

1

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30 April 2020

Katharina Scheibner

4

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30 April 2020

Marta Tarquis-Medina

5

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30 April 2020

Ciro Salinno

6

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30 April 2020

Silvia Schirge

7

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30 April 2020

Ingo Burtscher

8

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30 April 2020

Anika Böttcher

9

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30 April 2020

publication date

17 June 2019

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30 April 2020

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30 April 2020

volume

146

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30 April 2020

issue

12

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describes a project that uses

30 April 2020

pancreas

1 reference

A curated database reveals trends in single-cell transcriptomics

7 February 2021

https://www.nxn.se/single-cell-studies/data.tsv

10x Genomics Chromium

1 reference

A curated database reveals trends in single-cell transcriptomics

https://www.nxn.se/single-cell-studies/data.tsv

Diffusion pseudotime robustly reconstructs lineage branching

7 February 2021

cites work

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Neurog3 gene dosage regulates allocation of endocrine and exocrine cell fates in the developing mouse pancreas

1 April 2022

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1 April 2022

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Dynamics of chromatin marks and the role of JMJD3 during pancreatic endocrine cell fate commitment

1 April 2022

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Precommitment low-level Neurog3 expression defines a long-lived mitotic endocrine-biased progenitor pool that drives production of endocrine-committed cells

1 April 2022

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Single cell transcriptomic profiling of mouse pancreatic progenitors

1 April 2022

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Single-Cell Transcriptome Profiling of Mouse and hESC-Derived Pancreatic Progenitors

1 April 2022

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Opposing actions of Arx and Pax4 in endocrine pancreas development

1 April 2022

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EGFR signalling controls cellular fate and pancreatic organogenesis by regulating apicobasal polarity.

1 April 2022

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MFng is dispensable for mouse pancreas development and function

1 April 2022

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Lineage dynamics of murine pancreatic development at single-cell resolution

1 April 2022

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Pancreatic neurogenin 3-expressing cells are unipotent islet precursors

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Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming

1 April 2022

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Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse

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Foxa2 and Pdx1 cooperatively regulate postnatal maturation of pancreatic β-cells

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Sox9 ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas.

1 April 2022

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The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals

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Cellular and molecular mechanisms coordinating pancreas development

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Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis

1 April 2022

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An integrated cell purification and genomics strategy reveals multiple regulators of pancreas development

1 April 2022

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Inferring population dynamics from single-cell RNA-sequencing time series data

1 April 2022

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1 April 2022

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Loss of α2δ-1 Calcium Channel Subunit Function Increases the Susceptibility for Diabetes

1 April 2022

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Defining Lineage Potential and Fate Behavior of Precursors during Pancreas Development

1 April 2022

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A Peninsular Structure Coordinates Asynchronous Differentiation with Morphogenesis to Generate Pancreatic Islets

1 April 2022

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Planar cell polarity controls pancreatic beta cell differentiation and glucose homeostasis.

1 April 2022

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Neurogenin 3 is essential for the proper specification of gastric enteroendocrine cells and the maintenance of gastric epithelial cell identity

1 April 2022

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Bicaudal C1 promotes pancreatic NEUROG3 endocrine progenitor differentiation and ductal morphogenesis

1 April 2022

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PAGA: graph abstraction reconciles clustering with trajectory inference through a topology preserving map of single cells

1 April 2022

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1 April 2022

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1 April 2022

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Pancreas organogenesis: From bud to plexus to gland

1 April 2022

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Induction of pancreatic islet cell differentiation by the neurogenin-neuroD cascade

1 April 2022

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Cell cycle-dependent differentiation dynamics balances growth and endocrine differentiation in the pancreas

1 April 2022

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https://opencitations.net/index/coci/api/v1/references/10.1242/DEV.173849

Neurogenin3 initiates stepwise delamination of differentiating endocrine cells during pancreas development.

1 April 2022

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https://opencitations.net/index/coci/api/v1/references/10.1242/DEV.173849

Neurogenin3 inhibits proliferation in endocrine progenitors by inducing Cdkn1a

1 April 2022

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https://opencitations.net/index/coci/api/v1/references/10.1242/DEV.173849

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

1 April 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1242/DEV.173849

Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3

1 April 2022

1 reference

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Multi-site Neurogenin3 Phosphorylation Controls Pancreatic Endocrine Differentiation.

1 April 2022

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SOX4 cooperates with neurogenin 3 to regulate endocrine pancreas formation in mouse models.

1 April 2022

1 reference

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Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration

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1 reference

https://opencitations.net/index/coci/api/v1/references/10.1242/DEV.173849

SOX9 is required for maintenance of the pancreatic progenitor cell pool

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1 reference

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Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types.

1 April 2022

1 reference

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Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth

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1 reference

https://opencitations.net/index/coci/api/v1/references/10.1242/DEV.173849

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Defining multistep cell fate decision pathways during pancreatic development at single-cell resolution

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1 reference

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The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells

1 April 2022

1 reference

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Phosphorylation of NEUROG3 Links Endocrine Differentiation to the Cell Cycle in Pancreatic Progenitors.

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1 reference

https://opencitations.net/index/coci/api/v1/references/10.1242/DEV.173849

p120ctn-Mediated Organ Patterning Precedes and Determines Pancreatic Progenitor Fate

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1 reference

https://opencitations.net/index/coci/api/v1/references/10.1242/DEV.173849

Modelling the endocrine pancreas in health and disease

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1 reference

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Pancreatic islet progenitor cells in neurogenin 3-yellow fluorescent protein knock-add-on mice.

1 April 2022

1 reference

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Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity

1 April 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1242/DEV.173849

Feedback control of growth, differentiation, and morphogenesis of pancreatic endocrine progenitors in an epithelial plexus niche.

1 April 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1242/DEV.173849

Notch 2-positive progenitors with the intrinsic ability to give rise to pancreatic ductal cells

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1 reference

https://opencitations.net/index/coci/api/v1/references/10.1242/DEV.173849

INSM1 functions as a transcriptional repressor of the neuroD/beta2 gene through the recruitment of cyclin D1 and histone deacetylases

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1 reference

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Homology arms of targeting vectors for gene insertions and CRISPR/Cas9 technology: size does not matter; quality control of targeted clones does

1 April 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1242/DEV.173849

Preservation of proliferating pancreatic progenitor cells by Delta-Notch signaling in the embryonic chicken pancreas

1 April 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1242/DEV.173849

A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation

1 April 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1242/DEV.173849

RNA velocity of single cells

1 April 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1242/DEV.173849

Notch signalling controls pancreatic cell differentiation

1 April 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1242/DEV.173849

ROCK-nmMyoII, Notch and Neurog3 gene-dosage link epithelial morphogenesis with cell fate in the pancreatic endocrine-progenitor niche

1 April 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1242/DEV.173849

Identification of Enteroendocrine Regulators by Real-Time Single-Cell Differentiation Mapping

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1 reference

https://opencitations.net/index/coci/api/v1/references/10.1242/DEV.173849

A multipotent progenitor domain guides pancreatic organogenesis

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1 reference

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1 April 2022

Identifiers

DOI

10.1242/DEV.173849

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31160421 AND SRC:MED&resulttype=core&format=json

30 April 2020

1 reference