Effects of an Oral CRTh2 Antagonist (AZD1981) on Eosinophil Activity and Symptoms in Chronic Spontaneous Urticaria (Q92414706)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30879003 AND SRC:MED&resulttype=core&format=json

29 April 2020

title

Effects of an Oral CRTh2 Antagonist (AZD1981) on Eosinophil Activity and Symptoms in Chronic Spontaneous Urticaria (English)

1 reference

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29 April 2020

1 reference

chronic spontaneous urticaria

1 reference

Eric Tyrell Oliver

1

1 reference

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29 April 2020

Kris Chichester

2

1 reference

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29 April 2020

Kelly Devine

3

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29 April 2020

Patricia Meghan Sterba

4

1 reference

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29 April 2020

Craig Wegner

5

1 reference

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29 April 2020

Becky Marie Vonakis

6

1 reference

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29 April 2020

Sarbjit Singh Saini

7

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29 April 2020

publication date

15 March 2019

1 reference

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International Archives of Allergy and Immunology

29 April 2020

published in

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29 April 2020

volume

179

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29 April 2020

issue

1

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29 April 2020

page(s)

21-30

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Efficacy and safety of the CRTh2 antagonist AZD1981 as add-on therapy to inhaled corticosteroids and long-acting β2-agonists in patients with atopic asthma.

29 April 2020

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Effect of Omalizumab on Blood Basophil Counts in Patients with Chronic Idiopathic/Spontaneous Urticaria

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Altered expression of chemoattractant receptor-homologous molecule expressed on T(H)2 cells on blood basophils and eosinophils in patients with chronic spontaneous urticaria.

17 February 2021

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Interval shifts in basophil measures correlate with disease activity in chronic spontaneous urticaria

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Anti-eosinophil activity and clinical efficacy of the CRTH2 antagonist OC000459 in eosinophilic esophagitis

17 February 2021

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CRTH2 antagonists in the treatment of allergic responses involving TH2 cells, basophils, and eosinophils

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Biochemical and pharmacological characterization of AZD1981, an orally available selective DP2 antagonist in clinical development for asthma

17 February 2021

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The CRTH2 antagonist OC000459 reduces nasal and ocular symptoms in allergic subjects exposed to grass pollen, a randomised, placebo-controlled, double-blind trial

17 February 2021

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Evaluating the minimally important difference of the urticaria activity score and other measures of disease activity in patients with chronic idiopathic urticaria

17 February 2021

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D-type prostanoid receptor enhances the signaling of chemoattractant receptor–homologous molecule expressed on TH2 cells

17 February 2021

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A randomized, double-blind, placebo-controlled study of the CRTH2 antagonist OC000459 in moderate persistent asthma

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17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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Expression of prostaglandin D synthase and the prostaglandin D2 receptors DP and CRTH2 in human nasal mucosa

17 February 2021

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17 February 2021

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17 February 2021

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Blood basophil numbers in chronic ordinary urticaria and healthy controls: diurnal variation, influence of loratadine and prednisolone and relationship to disease activity

17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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Local effects of synthetic leukotrienes (LTC4, LTD4, LTE4, and LTB4) in human skin

17 February 2021

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Comparative vascular effects of histamine, prostaglandin (PG) D2 and its metabolite 9alpha, 11beta-PGF2 in human skin

17 February 2021

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Differential release of histamine and eicosanoids from human skin mast cells activated by IgE-dependent and non-immunological stimuli

17 February 2021

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Cutaneous late-phase response to allergen. Mediator release and inflammatory cell infiltration

17 February 2021

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In vivo antigen-induced cutaneous mediator release: Simultaneous comparisons of histamine, tryptase, and prostaglandin D2 release and the effect of oral corticosteroid administration†

17 February 2021

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17 February 2021

Identifiers

DOI

10.1159/000496162

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30879003 AND SRC:MED&resulttype=core&format=json

29 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30879003 AND SRC:MED&resulttype=core&format=json

29 April 2020

PubMed publication ID

30879003

1 reference