ROCK inhibitors upregulate the neuroprotective Parkin-mediated mitophagy pathway (Q92406985)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31900402 AND SRC:MED&resulttype=core&format=json

29 April 2020

title

ROCK inhibitors upregulate the neuroprotective Parkin-mediated mitophagy pathway (English)

1 reference

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29 April 2020

1

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29 April 2020

Alessandro Datti

5

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29 April 2020

George Angus McQuibban

7

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29 April 2020

author name string

Victoria Riccio

2

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29 April 2020

Mikhail Bashkurov

3

1 reference

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29 April 2020

Rediet Taddese

4

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29 April 2020

Peter N Lewis

6

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29 April 2020

publication date

3 January 2020

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29 April 2020

published in

Nature Communications

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29 April 2020

volume

11

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29 April 2020

issue

1

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29 April 2020

page(s)

88

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describes a project that uses

29 April 2020

scikit-image

1 reference

8 June 2022

https://europepmc.org/search?query=(METHODS:'scikit-image')

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Superoxide Dismutase (SOD)-mimetic M40403 Is Protective in Cell and Fly Models of Paraquat Toxicity: IMPLICATIONS FOR PARKINSON DISEASE.

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Deubiquitinating enzymes regulate PARK2-mediated mitophagy

17 February 2021

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Genetic mosaic analysis of a deleterious mitochondrial DNA mutation in Drosophila reveals novel aspects of mitochondrial regulation and function

17 February 2021

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High-content functional genomic screening to identify novel regulators of the PINK1-Parkin pathway.

17 February 2021

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The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy

17 February 2021

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17 February 2021

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Ubiquitin is phosphorylated by PINK1 to activate parkin

17 February 2021

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17 February 2021

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High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy

17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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Broad activation of the ubiquitin–proteasome system by Parkin is critical for mitophagy

17 February 2021

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17 February 2021

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17 February 2021

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PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

17 February 2021

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PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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17 February 2021

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Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

17 February 2021

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Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

17 February 2021

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Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons

17 February 2021

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Dopamine covalently modifies and functionally inactivates parkin

17 February 2021

1 reference

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Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin

17 February 2021

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S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function

17 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6941965

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

17 February 2021

1 reference

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Sequential treatment of SH-SY5Y cells with retinoic acid and brain-derived neurotrophic factor gives rise to fully differentiated, neurotrophic factor-dependent, human neuron-like cells

17 February 2021

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The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

17 February 2021

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Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

17 February 2021

1 reference

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Null mutation of copper/zinc superoxide dismutase in Drosophila confers hypersensitivity to paraquat and reduced longevity

17 February 2021

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6941965

10.1038/S41467-019-13781-3

17 February 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31900402 AND SRC:MED&resulttype=core&format=json

29 April 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31900402 AND SRC:MED&resulttype=core&format=json

29 April 2020

PubMed publication ID

31900402

1 reference