Tranexamic acid reduces heme cytotoxicity via the TLR4/TNF axis and ameliorates functional recovery after spinal cord injury (Q92260540)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31358003 AND SRC:MED&resulttype=core&format=json

28 April 2020

title

Tranexamic acid reduces heme cytotoxicity via the TLR4/TNF axis and ameliorates functional recovery after spinal cord injury (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31358003 AND SRC:MED&resulttype=core&format=json

28 April 2020

1 reference

5

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28 April 2020

author name string

Shingo Yoshizaki

1

1 reference

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28 April 2020

Ken Kijima

2

1 reference

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28 April 2020

Masamitsu Hara

3

1 reference

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28 April 2020

Takeyuki Saito

4

1 reference

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28 April 2020

Masatake Tanaka

6

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28 April 2020

Dai-Jiro Konno

7

1 reference

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28 April 2020

Yasuharu Nakashima

8

1 reference

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28 April 2020

Seiji Okada

9

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28 April 2020

publication date

29 July 2019

1 reference

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Journal of Neuroinflammation

28 April 2020

published in

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28 April 2020

volume

16

1 reference

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28 April 2020

issue

1

1 reference

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28 April 2020

page(s)

160

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describes a project that uses

28 April 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6661785/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Heme oxygenase-1 promotes neuron survival through down-regulation of neuronal NLRP1 expression after spinal cord injury

23 February 2021

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Red alert: labile heme is an alarmin

23 February 2021

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Endogenous plasminogen activators mediate progressive intracerebral hemorrhage after traumatic brain injury in mice

23 February 2021

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Tranexamic acid--an old drug still going strong and making a revival

23 February 2021

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Classifying types of disseminated intravascular coagulation: clinical and animal models

23 February 2021

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Acute hyperglycemia impairs functional improvement after spinal cord injury in mice and humans

23 February 2021

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23 February 2021

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Hemolysis exacerbates hyperfibrinolysis, whereas platelolysis shuts down fibrinolysis: evolving concepts of the spectrum of fibrinolysis in response to severe injury

23 February 2021

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Heme, an essential nutrient from dietary proteins, critically impacts diverse physiological and pathological processes.

23 February 2021

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Characterization of vascular disruption and blood-spinal cord barrier permeability following traumatic spinal cord injury

23 February 2021

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Hemostasis and alterations of the central nervous system

23 February 2021

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Ly6C Ly6G- Myeloid-derived suppressor cells play a critical role in the resolution of acute inflammation and the subsequent tissue repair process after spinal cord injury.

23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis

23 February 2021

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Neurological recovery is impaired by concurrent but not by asymptomatic pre-existing spinal cord compression after traumatic spinal cord injury

23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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Tissue-type plasminogen activator (t-PA) is stored in Weibel-Palade bodies in human endothelial cells both in vitro and in vivo

23 February 2021

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23 February 2021

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Intravascular hemolysis increases atherogenicity of diet-induced hypercholesterolemia in rabbits in spite of heme oxygenase-1 gene and protein induction

23 February 2021

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Tranexamic acid: a review of its use in surgery and other indications

23 February 2021

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CNS fibrinolysis: a review of the literature with a pediatric emphasis

23 February 2021

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Expression of tissue plasminogen activator in cerebral capillaries: possible fibrinolytic function of the blood-brain barrier

23 February 2021

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Incidence, characteristics, and outcome of spinal cord injury at trauma centers in North America

23 February 2021

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Extracellular proteolysis in the adult murine brain

23 February 2021

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Post-traumatic spinal epidural hematoma

23 February 2021

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Plasminogen activator-plasmin system and neuronal migration

23 February 2021

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Accelerated autoxidation and heme loss due to instability of sickle hemoglobin

23 February 2021

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Degradation of underlying extracellular matrix by sensory neurons during neurite outgrowth

23 February 2021

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The coagulation cascade: initiation, maintenance, and regulation

23 February 2021

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The binding of tranexamic acid to native (Glu) and modified (Lys) human plasminogen and its effect on conformation

23 February 2021

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10.1186/S12974-019-1536-Y

23 February 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31358003 AND SRC:MED&resulttype=core&format=json

28 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31358003 AND SRC:MED&resulttype=core&format=json

28 April 2020

PubMed publication ID

31358003

1 reference