Neuroinflammation in frontotemporal dementia (Q92035807)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31324897 AND SRC:MED&resulttype=core&format=json

26 April 2020

review article

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title

Neuroinflammation in frontotemporal dementia (English)

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26 April 2020

main subject

frontotemporal dementia

1 reference

1

1 reference

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26 April 2020

Glenda Halliday

6

1 reference

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26 April 2020

Jillian J. Kril

11

1 reference

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26 April 2020

7

John R Hodges

1 reference

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26 April 2020

4

Olivier Piguet

1 reference

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26 April 2020

5

Lars M Ittner

1 reference

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26 April 2020

3

Carol Dobson-Stone

1 reference

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26 April 2020

9

Clement T Loy

1 reference

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26 April 2020

2

Eryn L Werry

1 reference

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26 April 2020

author name string

Matthew C Kiernan

8

1 reference

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26 April 2020

Michael Kassiou

10

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26 April 2020

publication date

19 July 2019

1 reference

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26 April 2020

published in

Nature Reviews Neurology

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26 April 2020

volume

15

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26 April 2020

issue

9

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26 April 2020

page(s)

540-555

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The classification, genetics and neuropathology of frontotemporal dementia. Introduction to the special topic papers: Part I.

26 April 2020

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Innate immune activation in neurodegenerative disease

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Common inflammatory mechanisms in Lewy body disease and Alzheimer disease

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Cytokine production of activated microglia and decrease in neurotrophic factors of neurons in the hippocampus of Lewy body disease brains.

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7 January 2021

Inflammatory Response in the CNS: Friend or Foe?

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7 January 2021

Neuroinflammation in Alzheimer's disease

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Parkinson's disease dementia: a neural networks perspective

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Inflammatory processes in amyotrophic lateral sclerosis

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CNS inflammation and neurodegeneration

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7 January 2021

How neuroinflammation contributes to neurodegeneration

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DAMPs, PAMPs and alarmins: all we need to know about danger

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7 January 2021

Inside, outside, upside down: damage-associated molecular-pattern molecules (DAMPs) and redox

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7 January 2021

Neuroinflammation: the devil is in the details

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7 January 2021

The resolution of neuroinflammation in neurodegeneration: leukocyte recruitment via the choroid plexus.

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7 January 2021

Mechanisms underlying inflammation in neurodegeneration

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7 January 2021

Neuroimmune regulation of microglial activity involved in neuroinflammation and neurodegenerative diseases

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7 January 2021

Imaging and fluid biomarkers in frontotemporal dementia.

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7 January 2021

Microglia and mast cells: two tracks on the road to neuroinflammation

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7 January 2021

Neuroinflammation and blood-brain barrier changes in capillary amyloid angiopathy.

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7 January 2021

Blood-brain barrier breakdown, neuroinflammation, and cognitive decline in older adults

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7 January 2021

Blood-brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders

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7 January 2021

The blood-brain barrier in health and chronic neurodegenerative disorders

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7 January 2021

In vivo detection of microglial activation in frontotemporal dementia

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7 January 2021

Patterns of microglial cell activation in frontotemporal lobar degeneration

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7 January 2021

Patterns of Microglial Cell Activation in Alzheimer Disease and Frontotemporal Lobar Degeneration

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7 January 2021

Regional and cellular pathology in frontotemporal dementia: relationship to stage of disease in cases with and without Pick bodies

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7 January 2021

Quantitative neurohistological features of frontotemporal degeneration

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7 January 2021

Autoimmunity and Frontotemporal Dementia

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7 January 2021

Diverse Requirements for Microglial Survival, Specification, and Function Revealed by Defined-Medium Cultures

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7 January 2021

A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease

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Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy.

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7 January 2021

Translocator protein 18 kDa (TSPO): old dogma, new mice, new structure, and new questions for neuroprotection

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7 January 2021

Translational evaluation of translocator protein as a marker of neuroinflammation in schizophrenia

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7 January 2021

The macrophage marker translocator protein (TSPO) is down-regulated on pro-inflammatory 'M1' human macrophages

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7 January 2021

Increased Expression of Translocator Protein (TSPO) Marks Pro-inflammatory Microglia but Does Not Predict Neurodegeneration

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7 January 2021

Pro-inflammatory activation of primary microglia and macrophages increases 18 kDa translocator protein expression in rodents but not humans.

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7 January 2021

Pathological correlates of white matter hyperintensities in a case of progranulin mutation associated frontotemporal dementia

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7 January 2021

Presence of Reactive Microglia and Neuroinflammatory Mediators in a Case of Frontotemporal Dementia with P301S Mutation

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7 January 2021

Microglial activation correlates with disease progression and upper motor neuron clinical symptoms in amyotrophic lateral sclerosis

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7 January 2021

New tools for studying microglia in the mouse and human CNS.

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7 January 2021

TMEM119 marks a subset of microglia in the human brain

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7 January 2021

A proteomic network approach across the ALS-FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain.

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7 January 2021

Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer's Disease Not Evident in Mouse Models

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7 January 2021

Does inflammation in an autoimmune disease differ from inflammation in neurodegenerative diseases? Possible implications for therapy

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7 January 2021

Autoimmune Aspects of Neurodegenerative and Psychiatric Diseases: A Template for Innovative Therapy

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7 January 2021

Biomarkers of Neurodegeneration in Autoimmune-Mediated Encephalitis

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7 January 2021

Neuronal surface antigen antibodies in limbic encephalitis: clinical-immunologic associations.

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7 January 2021

A novel non-rapid-eye movement and rapid-eye-movement parasomnia with sleep breathing disorder associated with antibodies to IgLON5: a case series, characterisation of the antigen, and post-mortem study

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7 January 2021

Autoimmune Frontotemporal Dementia: A New Nosological Entity?

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7 January 2021

Anti-AMPA GluA3 antibodies in Frontotemporal dementia: a new molecular target.

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7 January 2021

Antinuclear antibodies in Frontotemporal Dementia: the tip's of autoimmunity iceberg?

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7 January 2021

Increased serum GP88 (Progranulin) concentrations in rheumatoid arthritis

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7 January 2021

Serum progranulin irrelated with Breg cell levels, but elevated in RA patients, reflecting high disease activity

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7 January 2021

Upregulated expression level of the growth factor, progranulin, is associated with the development of primary Sjögren's syndrome

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7 January 2021

Progranulin is preferentially expressed in patients with psoriasis vulgaris and protects mice from psoriasis-like skin inflammation.

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7 January 2021

Progranulin: A key player in autoimmune diseases.

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7 January 2021

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD

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7 January 2021

Neurodegenerative disease: Frontotemporal dementia--time to target inflammation?

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7 January 2021

SMCR8 negatively regulates AKT and MTORC1 signaling to modulate lysosome biogenesis and tissue homeostasis

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7 January 2021

Prevalence of immunological diseases in a Finnish frontotemporal lobar degeneration cohort with the C9orf72 repeat expansion carriers and non-carriers

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7 January 2021

Could immunological mechanisms trigger neurodegeneration in frontotemporal dementia?

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7 January 2021

Genetics of FTLD: overview and what else we can expect from genetic studies

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7 January 2021

Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways

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7 January 2021

Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia

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7 January 2021

The rs75932628 and rs2234253 polymorphisms of the TREM2 gene were associated with susceptibility to frontotemporal lobar degeneration in Caucasian populations.

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7 January 2021

Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17

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7 January 2021

Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21

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7 January 2021

Strikingly different clinicopathological phenotypes determined by progranulin-mutation dosage

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7 January 2021

Portuguese family with the co-occurrence of frontotemporal lobar degeneration and neuronal ceroid lipofuscinosis phenotypes due to progranulin gene mutation

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7 January 2021

Immune system irregularities in lysosomal storage disorders.

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7 January 2021

Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival

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7 January 2021

Progranulin deficiency decreases gross neural connectivity but enhances transmission at individual synapses

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7 January 2021

Synaptic dysfunction in progranulin-deficient mice

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7 January 2021

Granulins, a novel class of peptide from leukocytes

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7 January 2021

Divergent patterns of cytosolic TDP-43 and neuronal progranulin expression following axotomy: implications for TDP-43 in the physiological response to neuronal injury

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7 January 2021

Progranulin expression is upregulated after spinal contusion in mice.

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7 January 2021

Exacerbated inflammatory responses related to activated microglia after traumatic brain injury in progranulin-deficient mice

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7 January 2021

Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury

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7 January 2021

Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice

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7 January 2021

Progranulin promotes peripheral nerve regeneration and reinnervation: role of notch signaling

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7 January 2021

Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation

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7 January 2021

Dissociation of frontotemporal dementia-related deficits and neuroinflammation in progranulin haploinsufficient mice

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7 January 2021

Loss of function mutations in the progranulin gene are related to pro-inflammatory cytokine dysregulation in frontotemporal lobar degeneration patients

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7 January 2021

Inflammatory molecules in Frontotemporal Dementia: cerebrospinal fluid signature of progranulin mutation carriers.

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7 January 2021

Molecular signature of disease onset in granulin mutation carriers: a gene expression analysis study

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7 January 2021

Conversion of proepithelin to epithelins: roles of SLPI and elastase in host defense and wound repair

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7 January 2021

Progranulin Is a Chemoattractant for Microglia and Stimulates Their Endocytic Activity

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7 January 2021

Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12).

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7 January 2021

Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS

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7 January 2021

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

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7 January 2021

Genetic models of C9orf72: what is toxic?

1 reference

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7 January 2021

Deletion of C9ORF72 results in motor neuron degeneration and stress sensitivity in C. elegans

1 reference

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7 January 2021

C9orf72 ablation causes immune dysregulation characterized by leukocyte expansion, autoantibody production, and glomerulonephropathy in mice.

1 reference

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7 January 2021

C9orf72 is required for proper macrophage and microglial function in mice

1 reference

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7 January 2021

Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease

1 reference

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7 January 2021

Full ablation of C9orf72 in mice causes immune system-related pathology and neoplastic events but no motor neuron defects

1 reference

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7 January 2021

Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss

1 reference

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7 January 2021

Neurodegeneration. C9ORF72 repeat expansions in mice cause TDP-43 pathology, neuronal loss, and behavioral deficits

1 reference

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7 January 2021

Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs

1 reference

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7 January 2021

C9orf72 BAC Mouse Model with Motor Deficits and Neurodegenerative Features of ALS/FTD.

1 reference

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7 January 2021

C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Human TBK1: A Gatekeeper of Neuroinflammation

1 reference

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7 January 2021

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

1 reference

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7 January 2021

Triggering the interferon antiviral response through an IKK-related pathway

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-kappaB-dependent gene transcription

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

TBK1: a new player in ALS linking autophagy and neuroinflammation.

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Copy number variations on chromosome 12q14 in patients with normal tension glaucoma

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

TBK1 gene duplication and normal-tension glaucoma.

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Copy number variations of TBK1 in Australian patients with primary open-angle glaucoma

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Heterozygous TBK1 mutations impair TLR3 immunity and underlie herpes simplex encephalitis of childhood

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Regulation of T-cell activation and migration by the kinase TBK1 during neuroinflammation

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Mutations of optineurin in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

SQSTM1 mutations in familial and sporadic amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

SQSTM1 mutations in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Whole-genome sequencing reveals important role for TBK1 and OPTN mutations in frontotemporal lobar degeneration without motor neuron disease

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

TBK-1 Promotes Autophagy-Mediated Antimicrobial Defense by Controlling Autophagosome Maturation

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

TREMs in the immune system and beyond

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Distribution and signaling of TREM2/DAP12, the receptor system mutated in human polycystic lipomembraneous osteodysplasia with sclerosing leukoencephalopathy dementia

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

TREM2 in Neurodegenerative Diseases

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

TREM2, Microglia, and Neurodegenerative Diseases.

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Attenuated inflammatory response in triggering receptor expressed on myeloid cells 2 (TREM2) knock-out mice following stroke

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Triggering receptor expressed on myeloid cells 2 (TREM2) deficiency attenuates phagocytic activities of microglia and exacerbates ischemic damage in experimental stroke.

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Triggering Receptor Expressed on Myeloid Cells 2 Deficiency Alters Acute Macrophage Distribution and Improves Recovery after Traumatic Brain Injury

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

TREM2 sustains microglial expansion during aging and response to demyelination

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury.

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Nasu-Hakola syndrome: polycystic lipomembranous osteodysplasia with sclerosing leucoencephalopathy and presenile dementia

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Alzheimer's disease pathology in Nasu-Hakola disease brains.

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

New insights into the role of TREM2 in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Using exome sequencing to reveal mutations in TREM2 presenting as a frontotemporal dementia-like syndrome without bone involvement

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Homozygous TREM2 mutation in a family with atypical frontotemporal dementia

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

TREM2 variants and risk of Alzheimer's disease: a meta-analysis.

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Silencing of TREM2 exacerbates tau pathology, neurodegenerative changes, and spatial learning deficits in P301S tau transgenic mice

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Review: Fluid biomarkers for frontotemporal dementias

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Biological, Neuroimaging, and Neurophysiological Markers in Frontotemporal Dementia: Three Faces of the Same Coin

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis.

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Low plasma progranulin levels predict progranulin mutations in frontotemporal lobar degeneration.

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Plasma progranulin levels predict progranulin mutation status in frontotemporal dementia patients and asymptomatic family members

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Low Serum Progranulin Predicts the Presence of Mutations: A Prospective Study

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Progranulin plasma levels predict the presence of GRN mutations in asymptomatic subjects and do not correlate with brain atrophy: results from the GENFI study

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

CSF Biomarkers of Neurodegeneration in Progressive Non-fluent Aphasia and Other Forms of Frontotemporal Dementia: Clues for Pathomechanisms?

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Progranulin as a therapeutic target for dementia

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Results from a pilot study on amiodarone administration in monogenic frontotemporal dementia with granulin mutation

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Trehalose upregulates progranulin expression in human and mouse models of GRN haploinsufficiency: a novel therapeutic lead to treat frontotemporal dementia

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Targeted manipulation of the sortilin-progranulin axis rescues progranulin haploinsufficiency

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Cerebrospinal fluid soluble TREM2 levels in frontotemporal dementia differ by genetic and pathological subgroup

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Novel CSF biomarkers for frontotemporal lobar degenerations

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Increased intrathecal inflammatory activity in frontotemporal dementia: pathophysiological implications

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Plasma levels of progranulin and interleukin-6 in frontotemporal lobar degeneration

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Epidemiology of Alzheimer disease

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Microglia recapitulate a hematopoietic master regulator network in the aging human frontal cortex

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Control of microglial neurotoxicity by the fractalkine receptor

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Gene expression profiling in fetal, aged, and Alzheimer hippocampus: a continuum of stress-related signaling.

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Enlarged and phagocytic, but not primed, interleukin-1α-immunoreactive microglia increase with age in normal human brain

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Effect of age on proliferation-regulating factors in human adult neurogenic regions

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Gene regulation and DNA damage in the ageing human brain

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Immunosenescence of microglia and macrophages: impact on the ageing central nervous system.

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Innate immune memory in the brain shapes neurological disease hallmarks

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

The Lifespan and Turnover of Microglia in the Human Brain

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Coupled Proliferation and Apoptosis Maintain the Rapid Turnover of Microglia in the Adult Brain

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

New Insights into Microglia-Neuron Interactions: A Neuron's Perspective

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

A study on the association between infectious burden and Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

High BMI levels associate with reduced mRNA expression of IL10 and increased mRNA expression of iNOS (NOS2) in human frontal cortex

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Medical and environmental risk factors for sporadic frontotemporal dementia: a retrospective case-control study

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Traumatic brain injury causes frontotemporal dementia and TDP-43 proteolysis.

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Major Shifts in Glial Regional Identity Are a Transcriptional Hallmark of Human Brain Aging

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

A transcriptomic atlas of aged human microglia.

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Dystrophic microglia in the aging human brain

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Microglia Gone Rogue: Impacts on Psychiatric Disorders across the Lifespan

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Cellular senescence and the aging brain

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Aging causes morphological alterations in astrocytes and microglia in human substantia nigra pars compacta

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Glial reaction in the hippocampal formation is highly correlated with aging in human brain

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

GFAP mRNA increases with age in rat and human brain

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Increased levels of proinflammatory cytokines in the aged rat brain attenuate injury-induced cytokine response after excitotoxic damage.

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Microglial NFκB-TNFα hyperactivation induces obsessive-compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia.

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Progranulin Gene Therapy Improves Lysosomal Dysfunction and Microglial Pathology Associated with Frontotemporal Dementia and Neuronal Ceroid Lipofuscinosis.

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Living Neurons with Tau Filaments Aberrantly Expose Phosphatidylserine and Are Phagocytosed by Microglia

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

The Dual Role of Microglia in ALS: Mechanisms and Therapeutic Approaches

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Single-cell mass cytometry reveals distinct populations of brain myeloid cells in mouse neuroinflammation and neurodegeneration models

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Reduced frequency of T lymphocytes expressing CTLA-4 in frontotemporal dementia compared to Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Intrathecal levels of IL-6, IL-11 and LIF in Alzheimer's disease and frontotemporal lobar degeneration

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Intrathecal chemokine levels in Alzheimer disease and frontotemporal lobar degeneration.

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Interleukin-12 is reduced in cerebrospinal fluid of patients with Alzheimer's disease and frontotemporal dementia.

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Decreased expression of CCL3 in monocytes and CCR5 in lymphocytes from frontotemporal dementia as compared with Alzheimer's disease patients.

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

MCP-1 A-2518G polymorphism: effect on susceptibility for frontotemporal lobar degeneration and on cerebrospinal fluid MCP-1 levels

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Alterations in the Peripheral Immune System in Dementia

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Traumatic brain injury in hTau model mice: Enhanced acute macrophage response and altered long-term recovery.

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Cytokine profiling in patients with VCP-associated disease

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

The p97-UFD1L-NPL4 protein complex mediates cytokine-induced IκBα proteolysis

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Activation of the NLRP3 Inflammasome Is Associated with Valosin-Containing Protein Myopathy

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Metabolic dysfunction drives a mechanistically distinct proinflammatory phenotype in adipose tissue macrophages

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Optineurin insufficiency impairs IRF3 but not NF-κB activation in immune cells

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

The TBK1-binding domain of optineurin promotes type I interferon responses

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Optineurin deficiency in mice contributes to impaired cytokine secretion and neutrophil recruitment in bacteria-driven colitis

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

TDP-43 Depletion in Microglia Promotes Amyloid Clearance but Also Induces Synapse Loss

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

Differential Aging Analysis in Human Cerebral Cortex Identifies Variants in TMEM106B and GRN that Regulate Aging Phenotypes

1 reference

https://api.crossref.org/works/10.1038/S41582-019-0231-Z

7 January 2021

10.1038/S41582-019-0231-Z

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31324897 AND SRC:MED&resulttype=core&format=json

26 April 2020

1 reference