The coming of age of Langerhans cell histiocytosis (Q91934621)

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25 April 2020

title

The coming of age of Langerhans cell histiocytosis (English)

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Langerhans cell histiocytosis specific to childhood

25 April 2020

main subject

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2

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25 April 2020

Eli L Diamond

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25 April 2020

Florent Ginhoux

6

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25 April 2020

Christopher K Glass

7

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25 April 2020

Astrid van Halteren

10

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9

Barrett J Rollins

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25 April 2020

author name string

Carl E Allen

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25 April 2020

Matthew Collin

3

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25 April 2020

R Maarten Egeler

5

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25 April 2020

Milen Minkov

8

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25 April 2020

publication date

1 January 2020

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25 April 2020

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25 April 2020

volume

21

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issue

1

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page(s)

1-7

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The Nikolas Symposia and histiocytosis

25 April 2020

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Central nervous system disease in Langerhans cell histiocytosis

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Abundant expression of CD40 and CD40-ligand (CD154) in paediatric Langerhans cell histiocytosis lesions

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Disseminated histiocytoses biomarkers beyond BRAFV600E: frequent expression of PD-L1.

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Langerhans cell histiocytosis: fascinating dynamics of the dendritic cell-macrophage lineage.

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Aberrant chemokine receptor expression and chemokine production by Langerhans cells underlies the pathogenesis of Langerhans cell histiocytosis.

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7 January 2021

Cell-specific gene expression in Langerhans cell histiocytosis lesions reveals a distinct profile compared with epidermal Langerhans cells

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Expansion of regulatory T cells in patients with Langerhans cell histiocytosis

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Epigenomics and Single-Cell Sequencing Define a Developmental Hierarchy in Langerhans Cell Histiocytosis

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Expression of cell cycle-related gene products in Langerhans cell histiocytosis.

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p53 Expression in Langerhans Cell Histiocytosis

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High expression of markers of apoptosis in Langerhans cell histiocytosis

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7 January 2021

The presence of CXCR4 CD1a cells at onset of Langerhans cell histiocytosis is associated with a less favorable outcome

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7 January 2021

Langerhans'-cell histiocytosis (histiocytosis X)--a clonal proliferative disease.

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7 January 2021

Clonal proliferation of Langerhans cells in Langerhans cell histiocytosis

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7 January 2021

Acute leukemia in association with Langerhans cell histiocytosis

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7 January 2021

Recurrent BRAF mutations in Langerhans cell histiocytosis

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7 January 2021

Molecular characterization of the histiocytoses: Neoplasia of dendritic cells and macrophages.

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7 January 2021

High prevalence of BRAF V600E mutations in Erdheim-Chester disease but not in other non-Langerhans cell histiocytoses.

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7 January 2021

Association of both Langerhans cell histiocytosis and Erdheim-Chester disease linked to the BRAFV600E mutation.

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7 January 2021

Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms.

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7 January 2021

A novel fusion gene PLEKHA6-NTRK3 in langerhans cell histiocytosis

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7 January 2021

Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis.

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7 January 2021

Recurrent NRAS mutations in pulmonary Langerhans cell histiocytosis.

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7 January 2021

Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages

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7 January 2021

Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophages

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7 January 2021

Development of plasmacytoid and conventional dendritic cell subtypes from single precursor cells derived in vitro and in vivo

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7 January 2021

Origin, homeostasis and function of Langerhans cells and other langerin-expressing dendritic cells

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7 January 2021

The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting

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7 January 2021

Blood-derived dermal langerin dendritic cells survey the skin in the steady state

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7 January 2021

Langerin-expressing dendritic cells in human tissues are related to CD1c dendritic cells and distinct from Langerhans cells and CD141high XCR1 dendritic cells.

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7 January 2021

Notch is active in Langerhans cell histiocytosis and confers pathognomonic features on dendritic cells.

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7 January 2021

BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups

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7 January 2021

Hematopoietic origin of Langerhans cell histiocytosis and Erdheim-Chester disease in adults.

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7 January 2021

Functional evidence for derivation of systemic histiocytic neoplasms from hematopoietic stem/progenitor cells

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7 January 2021

RAF/MEK/extracellular signal-related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions

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7 January 2021

Identification of the Common Origins of Osteoclasts, Macrophages, and Dendritic Cells in Human Hematopoiesis

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7 January 2021

A genome-wide association study of LCH identifies a variant in SMAD6 associated with susceptibility.

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7 January 2021

Progress in understanding the pathogenesis of Langerhans cell histiocytosis: back to Histiocytosis X?

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Improved outcome in multisystem Langerhans cell histiocytosis is associated with therapy intensification

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7 January 2021

BRAF Mutation Correlates With High-Risk Langerhans Cell Histiocytosis and Increased Resistance to First-Line Therapy

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7 January 2021

Dramatic efficacy of vemurafenib in both multisystemic and refractory Erdheim-Chester disease and Langerhans cell histiocytosis harboring the BRAF V600E mutation

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7 January 2021

Targeted therapies in 54 patients with Erdheim-Chester disease, including follow-up after interruption (the LOVE study).

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7 January 2021

Clinical responses and persistent BRAF V600E blood cells in children with LCH treated with MAPK pathway inhibition

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7 January 2021

Longitudinal assessment of peripheral blood BRAFV600E levels in patients with Langerhans cell histiocytosis

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7 January 2021

A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease.

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7 January 2021

KRASG12D expression in lung-resident myeloid cells promotes pulmonary LCH-like neoplasm sensitive to statin treatment

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7 January 2021

Merkel cell polyomavirus and Langerhans cell neoplasm

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7 January 2021

10.1038/S41590-019-0558-Z

Identifiers

DOI

1 reference

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25 April 2020

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