Hepatic metabolic adaptation in a murine model of glutathione deficiency (Q91833658)

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25 April 2020

title

Hepatic metabolic adaptation in a murine model of glutathione deficiency (English)

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25 April 2020

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Rolando Garcia-Milian

3

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25 April 2020

Vasilis Vasiliou

6

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25 April 2020

author name string

Ying Chen

1

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25 April 2020

Srujana Golla

2

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25 April 2020

David C Thompson

4

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25 April 2020

Frank J Gonzalez

5

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25 April 2020

publication date

20 February 2019

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Chemico-biological Interactions

25 April 2020

published in

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25 April 2020

volume

303

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25 April 2020

page(s)

1-6

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Chronic Glutathione Depletion Confers Protection against Alcohol-induced Steatosis: Implication for Redox Activation of AMP-activated Protein Kinase Pathway

25 April 2020

cites work

1 reference

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Kinetic analysis of gluconate phosphorylation by human gluconokinase using isothermal titration calorimetry.

23 February 2021

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Metabolism of Sulfur-Containing Amino Acids in the Liver: A Link between Hepatic Injury and Recovery

23 February 2021

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Acetyl coenzyme A: a central metabolite and second messenger

23 February 2021

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Biochemical characterization of human gluconokinase and the proposed metabolic impact of gluconic acid as determined by constraint based metabolic network analysis

23 February 2021

1 reference

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Biomarkers of coordinate metabolic reprogramming in colorectal tumors in mice and humans.

23 February 2021

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Glutathione defense mechanism in liver injury: insights from animal models

23 February 2021

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Choline's role in maintaining liver function: new evidence for epigenetic mechanisms

23 February 2021

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Glutathione-Deficient Mice Are Susceptible to TCDD-Induced Hepatocellular Toxicity but Resistant to Steatosis

23 February 2021

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Lipid metabolism and body composition in Gclm(−/−) mice

23 February 2021

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Central role of mitochondria in drug-induced liver injury

23 February 2021

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Metabolic fingerprint of ischaemic cardioprotection: importance of the malate-aspartate shuttle.

23 February 2021

1 reference

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Attenuated progression of diet-induced steatohepatitis in glutathione-deficient mice

23 February 2021

1 reference

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Disruption of mitochondrial malate-aspartate shuttle activity in mouse blastocysts impairs viability and fetal growth

23 February 2021

1 reference

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Regulation of glutathione synthesis

23 February 2021

1 reference

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Oxidative mechanisms in the pathogenesis of alcoholic liver disease.

23 February 2021

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Interaction between the catalytic and modifier subunits of glutamate-cysteine ligase

23 February 2021

1 reference

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Glutamate cysteine ligase catalysis: dependence on ATP and modifier subunit for regulation of tissue glutathione levels

23 February 2021

1 reference

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Mitochondrial injury in steatohepatitis.

23 February 2021

1 reference

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Genetically altered mice to evaluate glutathione homeostasis in health and disease

23 February 2021

1 reference

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A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

23 February 2021

1 reference

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Amino acids as regulators and components of nonproteinogenic pathways

23 February 2021

1 reference

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Initial characterization of the glutamate-cysteine ligase modifier subunit Gclm(-/-) knockout mouse. Novel model system for a severely compromised oxidative stress response

23 February 2021

1 reference

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

23 February 2021

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Nonalcoholic steatosis and steatohepatitis. V. Mitochondrial dysfunction in steatohepatitis.

23 February 2021

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Knockout of the mouse glutamate cysteine ligase catalytic subunit (Gclc) gene: embryonic lethal when homozygous, and proposed model for moderate glutathione deficiency when heterozygous

23 February 2021

1 reference

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Glutathione deficiency produced by inhibition of its synthesis, and its reversal; Applications in research and therapy

23 February 2021

1 reference

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10.1016/J.CBI.2019.02.015

23 February 2021

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30794799 AND SRC:MED&resulttype=core&format=json

25 April 2020

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25 April 2020

PubMed publication ID

30794799

1 reference