Cutting off the fuel supply to calcium pumps in pancreatic cancer cells: role of pyruvate kinase-M2 (PKM2) (Q91826296)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31819190 AND SRC:MED&resulttype=core&format=json

24 April 2020

title

Cutting off the fuel supply to calcium pumps in pancreatic cancer cells: role of pyruvate kinase-M2 (PKM2) (English)

1 reference

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24 April 2020

1 reference

4

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24 April 2020

Jason I E Bruce

7

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24 April 2020

6

Lisa Barrett

1 reference

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24 April 2020

author name string

Andrew D James

1

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24 April 2020

Daniel A Richardson

2

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24 April 2020

In-Whan Oh

3

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24 April 2020

Thomas Attard

5

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24 April 2020

publication date

10 December 2019

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British Journal of Cancer

24 April 2020

published in

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24 April 2020

volume

122

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24 April 2020

issue

2

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24 April 2020

page(s)

266-278

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describes a project that uses

24 April 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC7052184/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

PKM2 regulates endothelial cell junction dynamics and angiogenesis via ATP production

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PKM2 is not required for pancreatic ductal adenocarcinoma

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Tyrosine Kinase Signaling in Cancer Metabolism: PKM2 Paradox in the Warburg Effect

23 February 2021

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Pyruvate kinase type M2 contributes to the development of pancreatic ductal adenocarcinoma by regulating the production of metabolites and reactive oxygen species

23 February 2021

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The responsively decreased PKM2 facilitates the survival of pancreatic cancer cells in hypoglucose

23 February 2021

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Pyruvate kinase M2 promotes pancreatic ductal adenocarcinoma invasion and metastasis through phosphorylation and stabilization of PAK2 protein.

23 February 2021

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Inhibition of Proliferation, Migration, and Invasion by Knockdown of Pyruvate Kinase-M2 (PKM2) in Ovarian Cancer SKOV3 and OVCAR3 Cells

23 February 2021

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Enhanced expression of the M2 isoform of pyruvate kinase is involved in gastric cancer development by regulating cancer-specific metabolism

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PKM2, cancer metabolism, and the road ahead

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23 February 2021

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Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma

23 February 2021

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Mounting Pressure in the Microenvironment: Fluids, Solids, and Cells in Pancreatic Ductal Adenocarcinoma

23 February 2021

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Pyruvate Kinase M2 and Lactate Dehydrogenase A Are Overexpressed in Pancreatic Cancer and Correlate with Poor Outcome

23 February 2021

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Knockdown of PKM2 Suppresses Tumor Growth and Invasion in Lung Adenocarcinoma

23 February 2021

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PKM2 Promotes Cell Survival and Invasion Under Metabolic Stress by Enhancing Warburg Effect in Pancreatic Ductal Adenocarcinoma

23 February 2021

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The Plasma Membrane Calcium Pump in Pancreatic Cancer Cells Exhibiting the Warburg Effect Relies on Glycolytic ATP.

23 February 2021

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PARP14 promotes the Warburg effect in hepatocellular carcinoma by inhibiting JNK1-dependent PKM2 phosphorylation and activation

23 February 2021

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Glycolysis is the primary bioenergetic pathway for cell motility and cytoskeletal remodeling in human prostate and breast cancer cells

23 February 2021

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PKM2 gene regulates the behavior of pancreatic cancer cells via mitogen-activated protein kinase pathways

23 February 2021

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Separation of metabolic supply and demand: aerobic glycolysis as a normal physiological response to fluctuating energetic demands in the membrane

23 February 2021

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Glycolytic ATP fuels the plasma membrane calcium pump critical for pancreatic cancer cell survival.

23 February 2021

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23 February 2021

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Proviral insertion in murine lymphomas 2 (PIM2) oncogene phosphorylates pyruvate kinase M2 (PKM2) and promotes glycolysis in cancer cells

23 February 2021

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PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells.

23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses

23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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Shikonin and its analogs inhibit cancer cell glycolysis by targeting tumor pyruvate kinase-M2

23 February 2021

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Ca²⁺ regulation of mitochondrial ATP synthesis visualized at the single cell level

23 February 2021

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23 February 2021

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23 February 2021

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Pancreatic cancer: epidemiology and risk factors

23 February 2021

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Pyruvate kinase type M2: a key regulator of the metabolic budget system in tumor cells

23 February 2021

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Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth

23 February 2021

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23 February 2021

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THE METABOLISM OF TUMORS IN THE BODY

23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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An enquiry into metabolite domains

23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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p53-mediated cell cycle arrest and apoptosis induced by shikonin via a caspase-9-dependent mechanism in human malignant melanoma A375-S2 cells

23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

23 February 2021

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Microcompartmentation, metabolic channelling and carbohydrate metabolism

23 February 2021

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Preferential support of Ca2 uptake in smooth muscle plasma membrane vesicles by an endogenous glycolytic cascade

23 February 2021

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Energy costs of ion pumping by animal tissues

23 February 2021

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Substrate channeling among glycolytic enzymes: Fact or fiction

23 February 2021

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Comparison of endogenous and exogenous sources of ATP in fueling Ca2 uptake in smooth muscle plasma membrane vesicles

23 February 2021

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10.1038/S41416-019-0675-3

23 February 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31819190 AND SRC:MED&resulttype=core&format=json

24 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31819190 AND SRC:MED&resulttype=core&format=json

24 April 2020

PubMed publication ID

31819190

1 reference