Ferroportin disease mutations influence manganese accumulation and cytotoxicity (Q91685806)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30247984 AND SRC:MED&resulttype=core&format=json

24 April 2020

title

Ferroportin disease mutations influence manganese accumulation and cytotoxicity (English)

1 reference

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24 April 2020

3

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24 April 2020

author name string

Eun-Kyung Choi

series ordinal

1

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24 April 2020

Trang-Tiffany Nguyen

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30247984 AND SRC:MED&resulttype=core&format=json

24 April 2020

Young Ah Seo

series ordinal

4

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24 April 2020

publication date

24 September 2018

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24 April 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30247984 AND SRC:MED&resulttype=core&format=json

24 April 2020

volume

33

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issue

2

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24 April 2020

page(s)

2228-2240

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describes a project that uses

24 April 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6338638/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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23 February 2021

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Direct Comparison of Manganese Detoxification/Efflux Proteins and Molecular Characterization of ZnT10 Protein as a Manganese Transporter.

23 February 2021

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Manganese Is Essential for Neuronal Health

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Ferroportin deficiency impairs manganese metabolism in flatiron mice

23 February 2021

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23 February 2021

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SLC30A10 is a cell surface-localized manganese efflux transporter, and parkinsonism-causing mutations block its intracellular trafficking and efflux activity

23 February 2021

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Comprehensive functional annotation of 18 missense mutations found in suspected hemochromatosis type 4 patients

23 February 2021

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23 February 2021

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Glial cell ceruloplasmin and hepcidin differentially regulate iron efflux from brain microvascular endothelial cells

23 February 2021

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23 February 2021

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Kinetics of manganese transport and gene expressions of manganese transport carriers in Caco-2 cell monolayers

23 February 2021

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Ferroportin diseases: functional studies, a link between genetic and clinical phenotype

23 February 2021

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Structure-function analysis of the human ferroportin iron exporter (SLC40A1): effect of hemochromatosis type 4 disease mutations and identification of critical residues.

23 February 2021

1 reference

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Iron depletion increases manganese uptake and potentiates apoptosis through ER stress

23 February 2021

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Manganese efflux in Parkinsonism: insights from newly characterized SLC30A10 mutations

23 February 2021

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Efflux function, tissue-specific expression and intracellular trafficking of the Zn transporter ZnT10 indicate roles in adult Zn homeostasis

23 February 2021

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23 February 2021

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Syndrome of hepatic cirrhosis, dystonia, polycythemia, and hypermanganesemia caused by mutations in SLC30A10, a manganese transporter in man

23 February 2021

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Mutations in SLC30A10 Cause Parkinsonism and Dystonia with Hypermanganesemia, Polycythemia, and Chronic Liver Disease

23 February 2021

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The iron transporter ferroportin can also function as a manganese exporter

23 February 2021

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Non-HFEHepatic Iron Overload

23 February 2021

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A histidine-rich motif mediates mitochondrial localization of ZnT2 to modulate mitochondrial function

23 February 2021

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23 February 2021

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G80S-linked ferroportin disease: Classical ferroportin disease in an Asian family and reclassification of the mutant as iron transport defective

23 February 2021

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Functional analysis of two single nucleotide polymorphisms in SLC30A2 (ZnT2): implications for mammary gland function and breast disease in women

23 February 2021

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23 February 2021

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23 February 2021

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Ferroportin is a manganese-responsive protein that decreases manganese cytotoxicity and accumulation

23 February 2021

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Functional analysis and theoretical modeling of ferroportin reveals clustering of mutations according to phenotype.

23 February 2021

1 reference

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Oxidative damage and neurodegeneration in manganese-induced neurotoxicity

23 February 2021

1 reference

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Hereditary hemochromatosis due to resistance to hepcidin: high hepcidin concentrations in a family with C326S ferroportin mutation

23 February 2021

1 reference

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Manganese exposure is cytotoxic and alters dopaminergic and GABAergic neurons within the basal ganglia

23 February 2021

1 reference

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The molecular basis of hepcidin-resistant hereditary hemochromatosis

23 February 2021

1 reference

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Iron overload in the Asian community

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6338638

Investigation of the biophysical and cell biological properties of ferroportin, a multipass integral membrane protein iron exporter

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6338638

Phenotypic expression of ferroportin disease in a family with the N144H mutation

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6338638

Global sequencing approach for characterizing the molecular background of hereditary iron disorders

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6338638

Implication of PTEN in production of reactive oxygen species and neuronal death in in vitro models of stroke and Parkinson's disease

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6338638

Magnetic resonance imaging to identify classic and nonclassic forms of ferroportin disease

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6338638

Wild-type and mutant ferroportins do not form oligomers in transfected cells.

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6338638

Lack of enterocyte iron accumulation in the ferroportin disease

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6338638

The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6338638

The molecular basis of ferroportin-linked hemochromatosis

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6338638

Functional consequences of ferroportin 1 mutations

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6338638

Autosomal dominant hereditary hemochromatosis associated with a novel ferroportin mutation and unique clinical features

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6338638

In vitro functional analysis of human ferroportin (FPN) and hemochromatosis-associated FPN mutations

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6338638

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6338638

Expression of the iron transporter ferroportin in synaptic vesicles and the blood-brain barrier

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6338638

A novel mutation in ferroportin1 is associated with haemochromatosis in a Solomon Islands patient

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6338638

The SLC40 basolateral iron transporter family (IREG1/ferroportin/MTP1)

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6338638

Molecular analyses of patients with hyperferritinemia and normal serum iron values reveal both L ferritin IRE and 3 new ferroportin (slc11A3) mutations

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6338638

Dominant hemochromatosis due to N144H mutation of SLC11A3: clinical and biological characteristics

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6338638

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6338638

A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6338638

A novel mammalian iron-regulated protein involved in intracellular iron metabolism

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6338638

Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6338638

A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6338638

Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6338638

23 February 2021

Identifiers

DOI

10.1096/FJ.201800831R

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30247984 AND SRC:MED&resulttype=core&format=json

24 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30247984 AND SRC:MED&resulttype=core&format=json

24 April 2020

PubMed publication ID

30247984

1 reference