Centrosome Amplification in Cancer Disrupts Autophagy and Sensitizes to Autophagy Inhibition (Q90662357)

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15 April 2020

title

Centrosome Amplification in Cancer Disrupts Autophagy and Sensitizes to Autophagy Inhibition (English)

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15 April 2020

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3

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15 April 2020

Mark E Burkard

5

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15 April 2020

author name string

Ryan A Denu

1

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15 April 2020

Gulpreet Kaur

2

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15 April 2020

Aparna Lakkaraju

4

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15 April 2020

publication date

11 October 2019

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Molecular Cancer Research

15 April 2020

published in

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volume

18

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issue

1

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page(s)

33-45

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Cytoskeletal elements are required for the formation and maturation of autophagic vacuoles

15 April 2020

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Causes and consequences of centrosome abnormalities in cancer

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12 December 2020

Cholesterol-mediated activation of acid sphingomyelinase disrupts autophagy in the retinal pigment epithelium

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The role for autophagy in cancer

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12 December 2020

Rampant centrosome amplification underlies more aggressive disease course of triple negative breast cancers

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12 December 2020

Mesenchymal Stromal Cells Derived From Crohn's Patients Deploy Indoleamine 2,3-dioxygenase-mediated Immune Suppression, Independent of Autophagy

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12 December 2020

Cell biology. Reversible centriole depletion with an inhibitor of Polo-like kinase 4.

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12 December 2020

Short- and long-term effects of chromosome mis-segregation and aneuploidy

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12 December 2020

Aneuploidy-induced cellular stresses limit autophagic degradation

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12 December 2020

Autophagy and proteins involved in vesicular trafficking

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12 December 2020

Aneuploidy triggers a TFEB-mediated lysosomal stress response

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12 December 2020

Identification of Selective Lead Compounds for Treatment of High-Ploidy Breast Cancer

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12 December 2020

Centrosome amplification induces high grade features and is prognostic of worse outcomes in breast cancer

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Prognostic relevance of autophagy markers LC3B and p62 in esophageal adenocarcinomas

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Pharmacological Inhibition of Centrosome Clustering by Slingshot-Mediated Cofilin Activation and Actin Cortex Destabilization.

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Autophagy controls centrosome number by degrading Cep63.

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Moving and positioning the endolysosomal system.

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Targeting Autophagy in Cancer: Update on Clinical Trials and Novel Inhibitors.

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Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy.

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12 December 2020

Centriole Overduplication is the Predominant Mechanism Leading to Centrosome Amplification in Melanoma

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12 December 2020

10.1158/1541-7786.MCR-19-0509

Identifiers

DOI

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15 April 2020

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