Identification of a novel oncogenic mutation of FGFR4 in gastric cancer (Q90641469)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31601997 AND SRC:MED&resulttype=core&format=json

15 April 2020

title

Identification of a novel oncogenic mutation of FGFR4 in gastric cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31601997 AND SRC:MED&resulttype=core&format=json

15 April 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31601997 AND SRC:MED&resulttype=core&format=json

15 April 2020

author name string

Takashi Futami

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31601997 AND SRC:MED&resulttype=core&format=json

15 April 2020

Tatsuya Kawase

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31601997 AND SRC:MED&resulttype=core&format=json

15 April 2020

Makoto Asaumi

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31601997 AND SRC:MED&resulttype=core&format=json

15 April 2020

Rumi Kihara

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31601997 AND SRC:MED&resulttype=core&format=json

15 April 2020

Nobuaki Shindoh

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31601997 AND SRC:MED&resulttype=core&format=json

15 April 2020

Sadao Kuromitsu

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31601997 AND SRC:MED&resulttype=core&format=json

15 April 2020

publication date

10 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31601997 AND SRC:MED&resulttype=core&format=json

15 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31601997 AND SRC:MED&resulttype=core&format=json

15 April 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31601997 AND SRC:MED&resulttype=core&format=json

15 April 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31601997 AND SRC:MED&resulttype=core&format=json

15 April 2020

page(s)

14627

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31601997 AND SRC:MED&resulttype=core&format=json

Gastric Cancer in the Era of Precision Medicine

15 April 2020

cites work

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

The FGF family: biology, pathophysiology and therapy

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

Fibroblast Growth Factor (FGF) Receptor/FGF Inhibitors: Novel Targets and Strategies for Optimization of Response of Solid Tumors

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

FGF10 signaling controls stomach morphogenesis

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

Targeting the fibroblast growth factor receptor 2 in gastric cancer: promise or pitfall?

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

An mRNA Gene Expression-Based Signature to Identify FGFR1-Amplified Estrogen Receptor-Positive Breast Tumors

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer.

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

Identification of targetable FGFR gene fusions in diverse cancers.

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

Kinase domain activation of FGFR2 yields high-grade lung adenocarcinoma sensitive to a Pan-FGFR inhibitor in a mouse model of NSCLC

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

Comprehensive molecular characterization of urothelial bladder carcinoma

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

Driver Fusions and Their Implications in the Development and Treatment of Human Cancers.

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

Single nucleotide polymorphism in fibroblast growth factor receptor 4 at codon 388 is associated with prognosis in high‐grade soft tissue sarcoma

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

The Fibroblast Growth Factor Receptor-4 Arg388 Allele is Associated with Gastric Cancer Progression

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

The genomic landscape of oesophagogastric junctional adenocarcinoma

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

Structural analysis of the human fibroblast growth factor receptor 4 kinase

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

Four classes of beta-hairpins in proteins

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

Knowledge-based prediction of protein structures and the design of novel molecules

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

Beta-hairpins in proteins revisited: lessons for de novo design

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

Ba/F3 transformation assays

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

ASP5878, a Novel Inhibitor of FGFR1, 2, 3, and 4, Inhibits the Growth of FGF19-Expressing Hepatocellular Carcinoma

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

ASP5878, a selective FGFR inhibitor, to treat FGFR3-dependent urothelial cancer with or without chemoresistance

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling Pathway

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

Fibroblast growth factor signaling in liver carcinogenesis

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

U.S. Food and Drug Administration approval: crizotinib for treatment of advanced or metastatic non-small cell lung cancer that is anaplastic lymphoma kinase positive.

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

Recurrent gain-of-function mutations of RHOA in diffuse-type gastric carcinoma

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

FGFR2 mutations are associated with poor outcomes in endometrioid endometrial cancer: An NRG Oncology/Gynecologic Oncology Group study

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

FGFR3 and TP53 mutation analysis in inverted urothelial papilloma: incidence and etiological considerations

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

Fibroblast growth factor receptors as treatment targets in clinical oncology

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

Landscape of activating cancer mutations in FGFR kinases and their differential responses to inhibitors in clinical use.

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

NTRK fusion-positive cancers and TRK inhibitor therapy

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor.

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

Elucidation of a four-site allosteric network in fibroblast growth factor receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

Altered fibroblast growth factor receptor 4 stability promotes prostate cancer progression

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

The selectivity of receptor tyrosine kinase signaling is controlled by a secondary SH2 domain binding site

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

A Molecular Brake in the Kinase Hinge Region Regulates the Activity of Receptor Tyrosine Kinases

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

A crystallographic snapshot of tyrosine trans-phosphorylation in action

1 reference

https://api.crossref.org/works/10.1038/S41598-019-51217-6

7 January 2021

10.1038/S41598-019-51217-6

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31601997 AND SRC:MED&resulttype=core&format=json

15 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31601997 AND SRC:MED&resulttype=core&format=json

15 April 2020

PubMed publication ID

31601997

1 reference