The Role of Calcium-Calcineurin-NFAT Signaling Pathway in Health and Autoimmune Diseases (Q90639753)

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15 April 2020

review article

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25 June 2021

The Role of Calcium-Calcineurin-NFAT Signaling Pathway in Health and Autoimmune Diseases (English)

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15 April 2020

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25 June 2021

Yune-Jung Park

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Seung-Ah Yoo

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Mingyo Kim

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Wan-Uk Kim

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10 March 2020

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25 June 2021

Frontiers in Immunology

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Creative Commons Attribution 4.0 International

15 April 2020

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1 reference

In vivo calcium elevations in thymocytes with T cell receptors that are specific for self ligands

25 June 2021

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NFAT proteins: key regulators of T-cell development and function

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STIM is a Ca2 sensor essential for Ca2 -store-depletion-triggered Ca2 influx

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STIM1 is a Ca2 sensor that activates CRAC channels and migrates from the Ca2 store to the plasma membrane

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Live-cell imaging reveals sequential oligomerization and local plasma membrane targeting of stromal interaction molecule 1 after Ca2 store depletion.

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Signalling to transcription: store-operated Ca2 entry and NFAT activation in lymphocytes.

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Orai1-mediated calcium entry plays a critical role in osteoclast differentiation and function by regulating activation of the transcription factor NFATc1

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Identifiers

DOI

10.3389/FIMMU.2020.00195

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32210952 AND SRC:MED&resulttype=core&format=json

15 April 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32210952 AND SRC:MED&resulttype=core&format=json

15 April 2020

PubMed publication ID

32210952

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