Genetically Encoded Fluorescent Biosensors Illuminate the Spatiotemporal Regulation of Signaling Networks (Q90494776)

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14 April 2020

title

Genetically Encoded Fluorescent Biosensors Illuminate the Spatiotemporal Regulation of Signaling Networks (English)

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14 April 2020

1

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14 April 2020

Sohum Mehta

series ordinal

2

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14 April 2020

Jin Zhang

series ordinal

3

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14 April 2020

publication date

14 December 2018

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14 April 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30550275 AND SRC:MED&resulttype=core&format=json

14 April 2020

volume

118

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14 April 2020

issue

24

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14 April 2020

page(s)

11707-11794

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Solubility and diffusion coefficient of adenosine 3':5'-monophosphate

14 April 2020

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12 December 2020

Compartmentalization of adenosine 3':5'-monophosphate and adenosine 3':5'-monophosphate-dependent protein kinase in heart tissue

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The calcium and magnesium binding sites on troponin and their role in the regulation of myofibrillar adenosine triphosphatase

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Iontophoresis of cyclic AMP

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Relationships between structural domains and function in the regulatory subunit of cAMP-dependent protein kinases I and II from porcine skeletal muscle

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Hormonally specific expression of cardiac protein kinase activity

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Fluorescence Energy Transfer as a Spectroscopic Ruler

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Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor

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Primary structure of the Aequorea victoria green-fluorescent protein

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PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activity

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12 December 2020

Crystallographic evidence of a large ligand-induced hinge-twist motion between the two domains of the maltodextrin binding protein involved in active transport and chemotaxis

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Molecular mechanisms of intracellular calcium excitability in X. laevis oocytes

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Neuronal Ca2 signalling takes the local route

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12 December 2020

β-Adrenergic receptor distribution in human and rat hippocampal formation: marked species differences

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12 December 2020

Kinetic analysis of cAMP-activated Na current in the molluscan neuron. A diffusion-reaction model

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12 December 2020

Fluorescence ratio imaging of cyclic AMP in single cells

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12 December 2020

Isolation and characterization of mutants of firefly luciferase which produce different colors of light.

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Calcium gradients underlying polarization and chemotaxis of eosinophils

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A model peptide with enhanced helicity

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Calcium oscillations in electrically non-excitable cells

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Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophores

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Fluorescent probes of cell signaling

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ATP-sensitive potassium channel and bursting in the pancreatic beta cell. A theoretical study

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Measurement of cytosolic free Ca2 with quin2

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Quantitative autoradiography of central beta adrenoceptor subtypes: comparison of the effects of chronic treatment with desipramine or centrally administered l-isoproterenol

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Chemotaxis in eukaryotic cells: a focus on leukocytes and Dictyostelium

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A new generation of Ca2 indicators with greatly improved fluorescence properties

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Intracellular free calcium localization in neutrophils during phagocytosis

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A cyclic-3',5'-adenosine monophosphate dependent protein kinase from the adrenal cortex: comparison with a cyclic AMP binding protein.

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Molecular forms and subunit composition of a cyclic adenosine 3',5'-monophosphate-dependent protein kinase purified from bovine heart muscle

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Adenosine 3',5'-monophosphate-dependent protein kinase from adipose tissue.

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Activation of protein kinase by physiological concentrations of cyclic AMP.

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Preparation of homogeneous cyclic AMP-dependent protein kinase(s) and its subunits from rabbit skeletal muscle

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Characterization by in vitro complementation of a peptide corresponding to an operator-proximal segment of the β-galactosidase structural gene of Escherichia coli

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Selective activation of particulate cAMP-dependent protein kinase by isoproterenol and prostaglandin E1

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12 December 2020

Phosphorylation of acyl and dansyl derivatives of the peptide Leu-Arg-Arg-Ala-Ser-Leu-Gly by the cAMP-dependent protein kinase

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12 December 2020

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12 December 2020

Compartments of cyclic AMP and protein kinase in mammalian cardiomyocytes

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The time-course of Ca2 exchange with calmodulin, troponin, parvalbumin, and myosin in response to transient increases in Ca2

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12 December 2020

Renaturation of Aequorea green-fluorescent protein

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12 December 2020

Spatially Resolved Dynamics of cAMP and Protein Kinase A Subunits in Aplysia Sensory Neurons

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12 December 2020

Wavelength mutations and posttranslational autoxidation of green fluorescent protein

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12 December 2020

Improved green fluorescence

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12 December 2020

Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate.

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12 December 2020

A calmodulin-target peptide hybrid molecule with unique calcium-binding properties

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12 December 2020

The spatial distribution of calcium signals in squid presynaptic terminals.

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12 December 2020

Movement of the free catalytic subunit of cAMP-dependent protein kinase into and out of the nucleus can be explained by diffusion

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12 December 2020

Structural, functional, and evolutionary relationships among extracellular solute-binding receptors of bacteria

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12 December 2020

Spatial calcium buffering in saccular hair cells

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12 December 2020

Spectroscopic Characterization of a High-Affinity Calmodulin−Target Peptide Hybrid Molecule†

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12 December 2020

Engineering green fluorescent protein for improved brightness, longer wavelengths and fluorescence resonance energy transfer

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12 December 2020

Fluorescence resonance energy transfer between blue-emitting and red-shifted excitation derivatives of the green fluorescent protein.

1 reference

12 December 2020

Ultra-fast excited state dynamics in green fluorescent protein: multiple states and proton transfer

1 reference

12 December 2020

Crystal structure of firefly luciferase throws light on a superfamily of adenylate-forming enzymes

1 reference

12 December 2020

Atomic structure and specificity of bacterial periplasmic receptors for active transport and chemotaxis: variation of common themes

1 reference

12 December 2020

Circular permutation of polypeptide chains: implications for protein folding and stability

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12 December 2020

Mutations that suppress the thermosensitivity of green fluorescent protein

1 reference

12 December 2020

Tripping the switch fantastic: how a protein kinase cascade can convert graded inputs into switch-like outputs

1 reference

12 December 2020

Elementary and global aspects of calcium signalling

1 reference

12 December 2020

Imaging the hierarchical Ca2 signalling system in HeLa cells.

1 reference

12 December 2020

Structural basis for dual excitation and photoisomerization of the Aequorea victoria green fluorescent protein

1 reference

12 December 2020

Sequence motifs for calmodulin recognition

1 reference

12 December 2020

Detection in living cells of Ca2 -dependent changes in the fluorescence emission of an indicator composed of two green fluorescent protein variants linked by a calmodulin-binding sequence. A new class of fluorescent indicators

1 reference

12 December 2020

On/off blinking and switching behaviour of single molecules of green fluorescent protein

1 reference

12 December 2020

Monitoring protein-protein interactions in intact eukaryotic cells by beta-galactosidase complementation

1 reference

12 December 2020

Crystal structure and photodynamic behavior of the blue emission variant Y66H/Y145F of green fluorescent protein

1 reference

12 December 2020

Fluorescent indicators for Ca2 based on green fluorescent proteins and calmodulin

1 reference

12 December 2020

Impact of Cytoplasmic Calcium Buffering on the Spatial and Temporal Characteristics of Intercellular Calcium Signals in Astrocytes

1 reference

12 December 2020

A Genetically Encoded Optical Probe of Membrane Voltage

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12 December 2020

Progressive cyclic nucleotide-induced conformational changes in the cGMP-dependent protein kinase studied by small angle X-ray scattering in solution.

1 reference

12 December 2020

Signaling Through Scaffold, Anchoring, and Adaptor Proteins

1 reference

12 December 2020

Green Fluorescent Protein (GFP)-tagged Cysteine-rich Domains from Protein Kinase C as Fluorescent Indicators for Diacylglycerol Signaling in Living Cells

1 reference

12 December 2020

Green Fluorescent Protein as a Noninvasive Intracellular pH Indicator

1 reference

12 December 2020

Receptor-induced transient reduction in plasma membrane PtdIns(4,5)P2 concentration monitored in living cells

1 reference

12 December 2020

Crystal structure of troponin C in complex with troponin I fragment at 2.3-Å resolution

1 reference

12 December 2020

Measurement of cytosolic, mitochondrial, and Golgi pH in single living cells with green fluorescent proteins

1 reference

12 December 2020

Control of pulsatile 5-HT/insulin secretion from single mouse pancreatic islets by intracellular calcium dynamics

1 reference

12 December 2020

The molecular structure of green fluorescent protein

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12 December 2020

Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins

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12 December 2020

Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domains

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12 December 2020

The green fluorescent protein

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12 December 2020

Oligomerization domain-directed reassembly of active dihydrofolate reductase from rationally designed fragments.

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12 December 2020

G protein signaling events are activated at the leading edge of chemotactic cells

1 reference

12 December 2020

Structural basis of spectral shifts in the yellow-emission variants of green fluorescent protein

1 reference

12 December 2020

Visualization of phosphoinositides that bind pleckstrin homology domains: calcium- and agonist-induced dynamic changes and relationship to myo-[3H]inositol-labeled phosphoinositide pools

1 reference

12 December 2020

Protein kinase C as a molecular machine for decoding calcium and diacylglycerol signals

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12 December 2020

The fibronectin type III domain as a scaffold for novel binding proteins

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12 December 2020

Generation of destabilized green fluorescent protein as a transcription reporter

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12 December 2020

Phosphoinositide lipids as signaling molecules: common themes for signal transduction, cytoskeletal regulation, and membrane trafficking

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12 December 2020

Dynamic and quantitative Ca2 measurements using improved cameleons

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12 December 2020

The relationship between the free concentrations of Ca2 and Ca2 -calmodulin in intact cells

1 reference

12 December 2020

Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium

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12 December 2020

Akt/PKB localisation and 3' phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction

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12 December 2020

Cyclic AMP diffusion coefficient in frog olfactory cilia

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12 December 2020

Spatiotemporal dynamics of inositol 1,4,5-trisphosphate that underlies complex Ca2 mobilization patterns

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12 December 2020

1 reference

12 December 2020

Directional guidance of neuronal migration in the olfactory system by the protein Slit

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12 December 2020

Circular permutation and receptor insertion within green fluorescent proteins

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12 December 2020

Sensitivity of the yellow variant of green fluorescent protein to halides and nitrate

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12 December 2020

Site-directed mutagenesis of firefly luciferase active site amino acids: a proposed model for bioluminescence color.

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12 December 2020

Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization

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12 December 2020

The pleckstrin homology domains of protein kinase B and GRP1 (general receptor for phosphoinositides-1) are sensitive and selective probes for the cellular detection of phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 3,4,5-trisphos

1 reference

12 December 2020

Role of metallothionein in nitric oxide signaling as revealed by a green fluorescent fusion protein

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12 December 2020

A genetically encoded, fluorescent indicator for cyclic AMP in living cells

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12 December 2020

Polarization of chemoattractant receptor signaling during neutrophil chemotaxis

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12 December 2020

Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI

1 reference

12 December 2020

Mechanism and cellular applications of a green fluorescent protein-based halide sensor

1 reference

12 December 2020

A fluorescent indicator for visualizing cAMP-induced phosphorylation in vivo

1 reference

12 December 2020

Differential affinities of visual arrestin, beta arrestin1, and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors

1 reference

12 December 2020

Chemical and physiological characterization of fluo-4 Ca(2 )-indicator dyes

1 reference

12 December 2020

Calmodulin: a prototypical calcium sensor

1 reference

12 December 2020

Cyclic nucleotide-gated channels colocalize with adenylyl cyclase in regions of restricted cAMP diffusion

1 reference

12 December 2020

The use of pHluorins for optical measurements of presynaptic activity

1 reference

12 December 2020

Localized Rac activation dynamics visualized in living cells

1 reference

12 December 2020

Structure of the GAF domain, a ubiquitous signaling motif and a new class of cyclic GMP receptor

1 reference

12 December 2020

A genetically encoded ratiometric indicator for chloride: capturing chloride transients in cultured hippocampal neurons

1 reference

12 December 2020

The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms

1 reference

12 December 2020

Spatial sensing in fibroblasts mediated by 3' phosphoinositides

1 reference

12 December 2020

Fluorescent indicators for cyclic GMP based on cyclic GMP-dependent protein kinase Ialpha and green fluorescent proteins

1 reference

12 December 2020

Monitoring Agonist-induced Phospholipase C Activation in Live Cells by Fluorescence Resonance Energy Transfer

1 reference

12 December 2020

A high signal-to-noise Ca(2 ) probe composed of a single green fluorescent protein

1 reference

12 December 2020

Spatiotemporal dynamics of guanosine 3',5'-cyclic monophosphate revealed by a genetically encoded, fluorescent indicator

1 reference

12 December 2020

Running on Ran: nuclear transport and the mitotic spindle.

1 reference

12 December 2020

Mammalian MAP kinase signalling cascades

1 reference

12 December 2020

Circularly permuted green fluorescent proteins engineered to sense Ca2 .

1 reference

12 December 2020

Phosphoserine/threonine-binding domains

1 reference

12 December 2020

Subcellular targeting by membrane lipids

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12 December 2020

Rapid caspase-3 activation during apoptosis revealed using fluorescence-resonance energy transfer

1 reference

12 December 2020

Regulation and role of adenylyl cyclase isoforms

1 reference

12 December 2020

Compartmentation of G protein-coupled signaling pathways in cardiac myocytes

1 reference

12 December 2020

Receptor-mediated activation of heterotrimeric G-proteins in living cells

1 reference

12 December 2020

A clearer vision for in vivo imaging

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12 December 2020

PhosphoSerine/threonine binding domains: you can't pSERious?

1 reference

12 December 2020

Application of the fluorescence resonance energy transfer method for studying the dynamics of caspase-3 activation during UV-induced apoptosis in living HeLa cells

1 reference

12 December 2020

G-protein signaling through tubby proteins

1 reference

12 December 2020

Reducing the environmental sensitivity of yellow fluorescent protein. Mechanism and applications

1 reference

12 December 2020

A pair of fluorescent resonance energy transfer-based probes for tyrosine phosphorylation of the CrkII adaptor protein in vivo.

1 reference

12 December 2020

Lipid rafts and signal transduction

1 reference

12 December 2020

Green fluorescent protein-based halide indicators with improved chloride and iodide affinities

1 reference

12 December 2020

Spatio-temporal images of growth-factor-induced activation of Ras and Rap1.

1 reference

12 December 2020

Design and characterization of a DNA-encoded, voltage-sensitive fluorescent protein.

1 reference

12 December 2020

FRET-based detection of different conformations of MK2.

1 reference

12 December 2020

Transcriptional regulation by the phosphorylation-dependent factor CREB

1 reference

12 December 2020

Control of astrocyte Ca(2 ) oscillations and waves by oscillating translocation and activation of protein kinase C.

1 reference

12 December 2020

Bistability in the JNK cascade

1 reference

12 December 2020

Monitoring the activation state of the insulin receptor using bioluminescence resonance energy transfer

1 reference

12 December 2020

Spatial heterogeneity of calcium transient alternans during the early phase of myocardial ischemia in the blood-perfused rabbit heart

1 reference

12 December 2020

Phosphatidylinositol 3-phosphate is generated in phagosomal membranes.

1 reference

12 December 2020

Shedding light on disulfide bond formation: engineering a redox switch in green fluorescent protein

1 reference

12 December 2020

FRET-based in vivo Ca2 imaging by a new calmodulin-GFP fusion molecule

1 reference

12 December 2020

Membrane targeting of C2 domains of phospholipase C-delta isoforms

1 reference

12 December 2020

Novel green fluorescent protein-based ratiometric indicators for monitoring pH in defined intracellular microdomains

1 reference

12 December 2020

Crystal structure of Escherichia coli ketopantoate reductase at 1.7 A resolution and insight into the enzyme mechanism

1 reference

12 December 2020

A genetically targetable fluorescent probe of channel gating with rapid kinetics

1 reference

12 December 2020

Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering

1 reference

12 December 2020

Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells

1 reference

12 December 2020

A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications

1 reference

12 December 2020

Calmodulin is a limiting factor in the cell

1 reference

12 December 2020

Cardiac excitation-contraction coupling

1 reference

12 December 2020

A fluorescent resonant energy transfer-based biosensor reveals transient and regional myosin light chain kinase activation in lamella and cleavage furrows

1 reference

12 December 2020

Calmodulin as an ion channel subunit

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12 December 2020

Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes

1 reference

12 December 2020

Fluorescent indicators for imaging protein phosphorylation in single living cells

1 reference

12 December 2020

Protein-protein interactions monitored in mammalian cells via complementation of beta -lactamase enzyme fragments

1 reference

12 December 2020

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12 December 2020

Bromodomain: an acetyl-lysine binding domain

1 reference

12 December 2020

Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts

1 reference

12 December 2020

Probing the dynamics and functions of aurora B kinase in living cells during mitosis and cytokinesis

1 reference

12 December 2020

Single-cell fluorescence resonance energy transfer analysis demonstrates that caspase activation during apoptosis is a rapid process. Role of caspase-3.

1 reference

12 December 2020

Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation

1 reference

12 December 2020

Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells

1 reference

12 December 2020

Beta-lactamase protein fragment complementation assays as in vivo and in vitro sensors of protein protein interactions

1 reference

12 December 2020

A monomeric red fluorescent protein

1 reference

12 December 2020

Tumor suppressor PTEN mediates sensing of chemoattractant gradients.

1 reference

12 December 2020

Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis

1 reference

12 December 2020

A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity

1 reference

12 December 2020

Visualization of maltose uptake in living yeast cells by fluorescent nanosensors.

1 reference

12 December 2020

A functional link between glucokinase binding to insulin granules and conformational alterations in response to glucose and insulin

1 reference

12 December 2020

Visualizing PI3 kinase-mediated cell-cell signaling during Dictyostelium development

1 reference

12 December 2020

High-resolution structure of the pleckstrin homology domain of protein kinase b/akt bound to phosphatidylinositol (3,4,5)-trisphosphate

1 reference

12 December 2020

Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells

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12 December 2020

Cyclic nucleotide research -- still expanding after half a century

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12 December 2020

Network motifs: simple building blocks of complex networks

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12 December 2020

Confirmation by FRET in individual living cells of the absence of significant amyloid beta -mediated caspase 8 activation

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12 December 2020

Structure and regulation of the cAMP-binding domains of Epac2

1 reference

12 December 2020

Tuning FlaSh: redesign of the dynamics, voltage range, and color of the genetically encoded optical sensor of membrane potential

1 reference

12 December 2020

Green fluorescent protein variants as ratiometric dual emission pH sensors. 1. Structural characterization and preliminary application

1 reference

12 December 2020

Spatio-temporal activation of caspase revealed by indicator that is insensitive to environmental effects

1 reference

12 December 2020

The molecular basis of differential subcellular localization of C2 domains of protein kinase C-alpha and group IVa cytosolic phospholipase A2.

1 reference

12 December 2020

The state of lipid rafts: from model membranes to cells

1 reference

12 December 2020

Sniffers, buzzers, toggles and blinkers: dynamics of regulatory and signaling pathways in the cell

1 reference

12 December 2020

In vivo imaging of the dynamics of glucose uptake in the cytosol of COS-7 cells by fluorescent nanosensors

1 reference

12 December 2020

Monitoring conformational changes of proteins in cells by fluorescence lifetime imaging microscopy

1 reference

12 December 2020

Rational design of genetically encoded fluorescence resonance energy transfer-based sensors of cellular Cdc42 signaling

1 reference

12 December 2020

Molecular nanosprings in spider capture-silk threads

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12 December 2020

Phosphoinositide recognition domains

1 reference

12 December 2020

Communication between the regulatory and the catalytic region of the cAMP-responsive guanine nucleotide exchange factor Epac

1 reference

12 December 2020

Transition Metal Speciation in the Cell: Insights from the Chemistry of Metal Ion Receptors

1 reference

12 December 2020

Efficiently folding and circularly permuted variants of the Sapphire mutant of GFP

1 reference

12 December 2020

Fluorescent indicators for Akt/protein kinase B and dynamics of Akt activity visualized in living cells

1 reference

12 December 2020

Bistability in cell signaling: How to make continuous processes discontinuous, and reversible processes irreversible

1 reference

12 December 2020

A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C

1 reference

12 December 2020

AKAP7gamma is a nuclear RI-binding AKAP

1 reference

12 December 2020

Measurement of the millisecond activation switch of G protein-coupled receptors in living cells

1 reference

12 December 2020

Calcium signalling: dynamics, homeostasis and remodelling

1 reference

12 December 2020

Activity of Rho-family GTPases during cell division as visualized with FRET-based probes

1 reference

12 December 2020

SH2 and PTB domains in tyrosine kinase signaling

1 reference

12 December 2020

Structural basis of a phototropin light switch

1 reference

12 December 2020

Transcriptional regulation by calcium, calcineurin, and NFAT

1 reference

12 December 2020

The beginnings of immunofluorescence

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12 December 2020

Production of PtdInsP3 at endomembranes is triggered by receptor endocytosis

1 reference

12 December 2020

Development of a fluorescent nanosensor for ribose

1 reference

12 December 2020

Buffer kinetics shape the spatiotemporal patterns of IP3-evoked Ca2 signals

1 reference

12 December 2020

Genetic Engineering of an Allosterically Based Glucose Indicator Protein for Continuous Glucose Monitoring by Fluorescence Resonance Energy Transfer

1 reference

12 December 2020

Nonlinear magic: multiphoton microscopy in the biosciences

1 reference

12 December 2020

A positive-feedback-based bistable 'memory module' that governs a cell fate decision

1 reference

12 December 2020

Cell migration: integrating signals from front to back

1 reference

12 December 2020

Gi protein activation in intact cells involves subunit rearrangement rather than dissociation

1 reference

12 December 2020

Lateral phosphorylation propagation: an aspect of feedback signalling?

1 reference

12 December 2020

Mitochondrial pH monitored by a new engineered green fluorescent protein mutant.

1 reference

12 December 2020

Localized effects of cAMP mediated by distinct routes of protein kinase A.

1 reference

12 December 2020

Investigating mitochondrial redox potential with redox-sensitive green fluorescent protein indicators

1 reference

12 December 2020

Genetically encoded indicators of cellular calcium dynamics based on troponin C and green fluorescent protein

1 reference

12 December 2020

Gap junctional communication modulates agonist-induced calcium oscillations in transfected HeLa cells

1 reference

12 December 2020

Detection of multistability, bifurcations, and hysteresis in a large class of biological positive-feedback systems

1 reference

12 December 2020

Bicarbonate-responsive "soluble" adenylyl cyclase defines a nuclear cAMP microdomain

1 reference

12 December 2020

A ratiometric expressible FRET sensor for phosphoinositides displays a signal change in highly dynamic membrane structures in fibroblasts

1 reference

12 December 2020

Imaging dynamic redox changes in mammalian cells with green fluorescent protein indicators

1 reference

12 December 2020

An improved cyan fluorescent protein variant useful for FRET

1 reference

12 December 2020

Isoforms of mammalian adenylyl cyclase: multiplicities of signaling

1 reference

12 December 2020

Calcium signaling in chemorepellant Slit2-dependent regulation of neuronal migration

1 reference

12 December 2020

RalA activation at nascent lamellipodia of epidermal growth factor-stimulated Cos7 cells and migrating Madin-Darby canine kidney cells

1 reference

12 December 2020

Cyan-emitting and orange-emitting fluorescent proteins as a donor/acceptor pair for fluorescence resonance energy transfer

1 reference

12 December 2020

Real-time evaluation of myosin light chain kinase activation in smooth muscle tissues from a transgenic calmodulin-biosensor mouse

1 reference

12 December 2020

Imaging sites of N-wasp activity in lamellipodia and invadopodia of carcinoma cells

1 reference

12 December 2020

Functional stoichiometry and local enrichment of calmodulin interacting with Ca2 channels

1 reference

12 December 2020

Genetically encoded fluorescent reporters of histone methylation in living cells

1 reference

12 December 2020

Model systems, lipid rafts, and cell membranes

1 reference

12 December 2020

Mechanistic systems models of cell signaling networks: a case study of myocyte adrenergic regulation.

1 reference

12 December 2020

Cell cycle-dependent regulation of a human DNA helicase that localizes in DNA damage foci

1 reference

12 December 2020

A genetically encoded fluorescent reporter of histone phosphorylation in living cells

1 reference

12 December 2020

TRPV1 acts as proton channel to induce acidification in nociceptive neurons

1 reference

12 December 2020

Fluorescence resonance energy transfer-based analysis of cAMP dynamics in live neonatal rat cardiac myocytes reveals distinct functions of compartmentalized phosphodiesterases

1 reference

12 December 2020

Guiding neuronal growth cones using Ca2 signals.

1 reference

12 December 2020

Imaging phosphorylation dynamics of the epidermal growth factor receptor

1 reference

12 December 2020

Novel single chain cAMP sensors for receptor-induced signal propagation.

1 reference

12 December 2020

Expanded dynamic range of fluorescent indicators for Ca(2 ) by circularly permuted yellow fluorescent proteins.

1 reference

12 December 2020

Models of cell signaling pathways

1 reference

12 December 2020

Fluorescent biosensor for quantitative real-time measurements of inositol 1,4,5-trisphosphate in single living cells

1 reference

12 December 2020

Signaling in small subcellular volumes. I. Stochastic and diffusion effects on individual pathways

1 reference

12 December 2020

Hormonally specific phosphorylation of cardiac troponin I and activation of glycogen phosphorylase

1 reference

12 December 2020

Nitric oxide-sensitive guanylyl cyclase: structure and regulation

1 reference

12 December 2020

Periplasmic binding proteins: a versatile superfamily for protein engineering

1 reference

12 December 2020

APC/C and SCF: controlling each other and the cell cycle

1 reference

12 December 2020

Genetically encoded FRET probe for PKC activity based on pleckstrin

1 reference

12 December 2020

Single color fluorescent indicators of protein phosphorylation for multicolor imaging of intracellular signal flow dynamics

1 reference

12 December 2020

Oscillations in NF-kappaB signaling control the dynamics of gene expression

1 reference

12 December 2020

Fluorescent indicators of cAMP and Epac activation reveal differential dynamics of cAMP signaling within discrete subcellular compartments

1 reference

12 December 2020

Regulated fast nucleocytoplasmic shuttling observed by reversible protein highlighting

1 reference

12 December 2020

Detecting cAMP-induced Epac activation by fluorescence resonance energy transfer: Epac as a novel cAMP indicator

1 reference

12 December 2020

Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein

1 reference

12 December 2020

AKAP signalling complexes: focal points in space and time

1 reference

12 December 2020

Protein tagging and detection with engineered self-assembling fragments of green fluorescent protein

1 reference

12 December 2020

Spatio-temporal dynamics of protein kinase B/Akt signaling revealed by a genetically encoded fluorescent reporter

1 reference

12 December 2020

Bcl-2-mediated alterations in endoplasmic reticulum Ca2 analyzed with an improved genetically encoded fluorescent sensor

1 reference

12 December 2020

Building and breeding molecules to spy on cells and tumors

1 reference

12 December 2020

Evolutionary optimization of fluorescent proteins for intracellular FRET

1 reference

12 December 2020

Ras binding opens c-Raf to expose the docking site for mitogen-activated protein kinase kinase.

1 reference

12 December 2020

Real-time monitoring of receptor and G-protein interactions in living cells.

1 reference

12 December 2020

Real-time monitoring of ubiquitination in living cells by BRET.

1 reference

12 December 2020

Visualization of synaptic Ca2 /calmodulin-dependent protein kinase II activity in living neurons.

1 reference

12 December 2020

Ca2 transients control CNS neuronal migration

1 reference

12 December 2020

Visualizing the mechanical activation of Src.

1 reference

12 December 2020

Phosphoinositide phosphatase activity coupled to an intrinsic voltage sensor

1 reference

12 December 2020

A FRET-based probe for epidermal growth factor receptor bound non-covalently to a pair of synthetic amphipathic helixes.

1 reference

12 December 2020

Detection of glutamate release from neurons by genetically encoded surface-displayed FRET nanosensors

1 reference

12 December 2020

The crystal structure of Escherichia coli ketopantoate reductase with NADP bound

1 reference

12 December 2020

Interplay of Ca2 and cAMP signaling in the insulin-secreting MIN6 beta-cell line

1 reference

12 December 2020

Cygnets: in vivo characterization of novel cGMP indicators and in vivo imaging of intracellular cGMP.

1 reference

12 December 2020

Development of ERK Activity Sensor, an in vitro, FRET-based sensor of Extracellular Regulated Kinase activity.

1 reference

12 December 2020

A new type of bacteriophytochrome acts in tandem with a classical bacteriophytochrome to control the antennae synthesis in Rhodopseudomonas palustris

1 reference

12 December 2020

Locating inositol 1,4,5-trisphosphate in the nucleus and neuronal dendrites with genetically encoded fluorescent indicators

1 reference

12 December 2020

Construction and optimization of a family of genetically encoded metabolite sensors by semirational protein engineering.

1 reference

12 December 2020

Nonlinear structured-illumination microscopy: wide-field fluorescence imaging with theoretically unlimited resolution

1 reference

12 December 2020

Imaging the nanomolar range of nitric oxide with an amplifier-coupled fluorescent indicator in living cells

1 reference

12 December 2020

Insulin disrupts beta-adrenergic signalling to protein kinase A in adipocytes

1 reference

12 December 2020

The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways.

1 reference

12 December 2020

Stochastic simulation of chemical reactions with spatial resolution and single molecule detail

1 reference

12 December 2020

Dynamics of signaling by PKA.

1 reference

12 December 2020

Signal propagation from membrane messengers to nuclear effectors revealed by reporters of phosphoinositide dynamics and Akt activity

1 reference

12 December 2020

Coordinating ERK/MAPK signalling through scaffolds and inhibitors

1 reference

12 December 2020

Biosensors to measure inositol 1,4,5-trisphosphate concentration in living cells with spatiotemporal resolution

1 reference

12 December 2020

Seven-transmembrane receptor signaling through beta-arrestin

1 reference

12 December 2020

Dynamics of receptor/G protein coupling in living cells

1 reference

12 December 2020

Deep tissue two-photon microscopy

1 reference

12 December 2020

Re-engineering redox-sensitive green fluorescent protein for improved response rate

1 reference

12 December 2020

A FRET-based calcium biosensor with fast signal kinetics and high fluorescence change

1 reference

12 December 2020

Fluorescent sensors for rapid monitoring of intracellular cGMP

1 reference

12 December 2020

Gialpha and Gbeta subunits both define selectivity of G protein activation by alpha2-adrenergic receptors

1 reference

12 December 2020

A dual parameter FRET probe for measuring PKC and PKA activity in living cells

1 reference

12 December 2020

Mechanisms of mechanotransduction.

1 reference

12 December 2020

Isolated regulatory domains of cGMP-dependent protein kinase Ialpha and Ibeta retain dimerization and native cGMP-binding properties and undergo isoform-specific conformational changes

1 reference

12 December 2020

Dynamics of the Ras/ERK MAPK Cascade as Monitored by Fluorescent Probes

1 reference

12 December 2020

Oscillations of cyclic AMP in hormone-stimulated insulin-secreting beta-cells

1 reference

12 December 2020

Supersensitive Ras activation in dendrites and spines revealed by two-photon fluorescence lifetime imaging

1 reference

12 December 2020

Analysis of the spatiotemporal activation of rho GTPases using Raichu probes.

1 reference

12 December 2020

Mechanistic insight provided by glutaredoxin within a fusion to redox-sensitive yellow fluorescent protein

1 reference

12 December 2020

Cell-signalling dynamics in time and space

1 reference

12 December 2020

Novel, isotype-specific sensors for protein kinase A subunit interaction based on bioluminescence resonance energy transfer (BRET).

1 reference

12 December 2020

Imaging cellular signals in the heart in vivo: Cardiac expression of the high-signal Ca2 indicator GCaMP2.

1 reference

12 December 2020

Neutrophil polarization: spatiotemporal dynamics of RhoA activity support a self-organizing mechanism

1 reference

12 December 2020

A dark yellow fluorescent protein (YFP)-based Resonance Energy-Accepting Chromoprotein (REACh) for Förster resonance energy transfer with GFP.

1 reference

12 December 2020

Spatiotemporal dynamics of RhoA activity in migrating cells

1 reference

12 December 2020

Genetically encoded fluorescent indicator for intracellular hydrogen peroxide

1 reference

12 December 2020

Computational modeling of a new fluorescent biosensor for caspase proteolytic activity improves dynamic range

1 reference

12 December 2020

Analysis of a RanGTP-regulated gradient in mitotic somatic cells

1 reference

12 December 2020

A family of destabilized cyan fluorescent proteins as transcriptional reporters in S. cerevisiae

1 reference

12 December 2020

Development of a novel GFP-based ratiometric excitation and emission pH indicator for intracellular studies

1 reference

12 December 2020

Physical nature of bacterial cytoplasm.

1 reference

12 December 2020

Phosphatidylinositol 3-phosphate recognition and membrane docking by the FYVE domain.

1 reference

12 December 2020

Phytochrome structure and signaling mechanisms.

1 reference

12 December 2020

Annexin A4 self-association modulates general membrane protein mobility in living cells.

1 reference

12 December 2020

Live cell imaging of phosphoinositide dynamics with fluorescent protein domains

1 reference

12 December 2020

Ca2 indicators based on computationally redesigned calmodulin-peptide pairs

1 reference

12 December 2020

Zinc binding to a regulatory zinc-sensing domain monitored in vivo by using FRET

1 reference

12 December 2020

Understanding bistability in complex enzyme-driven reaction networks

1 reference

12 December 2020

Cytosolic inositol 1,4,5-trisphosphate dynamics during intracellular calcium oscillations in living cells

1 reference

12 December 2020

Restricted diffusion of a freely diffusible second messenger: mechanisms underlying compartmentalized cAMP signalling

1 reference

12 December 2020

Restricted diffusion of a freely diffusible second messenger: mechanisms underlying compartmentalized cAMP signalling

1 reference

12 December 2020

The amino-terminal B-Raf-specific region mediates calcium-dependent homo- and hetero-dimerization of Raf.

1 reference

12 December 2020

Subcellular dynamics of protein kinase A activity visualized by FRET-based reporters

1 reference

12 December 2020

Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM)

1 reference

12 December 2020

Nanoscale resolution in GFP-based microscopy

1 reference

12 December 2020

Targeting protein kinase C activity reporter to discrete intracellular regions reveals spatiotemporal differences in agonist-dependent signaling

1 reference

12 December 2020

Imaging intracellular fluorescent proteins at nanometer resolution

1 reference

12 December 2020

Systems analysis of PKA-mediated phosphorylation gradients in live cardiac myocytes

1 reference

12 December 2020

Probing the activation-promoted structural rearrangements in preassembled receptor-G protein complexes.

1 reference

12 December 2020

Ratiometric fluorescent sensor proteins with subnanomolar affinity for Zn(II) based on copper chaperone domains

1 reference

12 December 2020

Conversion of a putative Agrobacterium sugar-binding protein into a FRET sensor with high selectivity for sucrose

1 reference

12 December 2020

Rapid metabolism of glucose detected with FRET glucose nanosensors in epidermal cells and intact roots of Arabidopsis RNA-silencing mutants.

1 reference

12 December 2020

GTP hydrolysis by the Rho family GTPase TC10 promotes exocytic vesicle fusion.

1 reference

12 December 2020

Gs activation is time-limiting in initiating receptor-mediated signaling.

1 reference

12 December 2020

Imaging diacylglycerol dynamics at organelle membranes

1 reference

12 December 2020

Increases in mitochondrial reactive oxygen species trigger hypoxia-induced calcium responses in pulmonary artery smooth muscle cells

1 reference

12 December 2020

Calcium microdomains: organization and function

1 reference

12 December 2020

A novel analytical method for in vivo phosphate tracking

1 reference

12 December 2020

Cyclic AMP Imaging in Adult Cardiac Myocytes Reveals Far-Reaching β 1 -Adrenergic but Locally Confined β 2 -Adrenergic Receptor–Mediated Signaling

1 reference

12 December 2020

Monobodies: antibody mimics based on the scaffold of the fibronectin type III domain

1 reference

12 December 2020

Regulation of RalA GTPase by phosphatidylinositol 3-kinase as visualized by FRET probes

1 reference

12 December 2020

PGE(1) stimulation of HEK293 cells generates multiple contiguous domains with different [cAMP]: role of compartmentalized phosphodiesterases

1 reference

12 December 2020

A Cellular FRET-Based Sensor for β-O-GlcNAc, A Dynamic Carbohydrate Modification Involved in Signaling

1 reference

12 December 2020

Computational methodologies for modelling, analysis and simulation of signalling networks

1 reference

12 December 2020

Cardiac beta-adrenergic signaling: from subcellular microdomains to heart failure

1 reference

12 December 2020

Attractive axon guidance involves asymmetric membrane transport and exocytosis in the growth cone

1 reference

12 December 2020

Cell-based indicator to visualize picomolar dynamics of nitric oxide release from living cells

1 reference

12 December 2020

Calcium-dependent regulation of protein kinase D revealed by a genetically encoded kinase activity reporter

1 reference

12 December 2020

Genetically encoded fluorescent indicators to visualize protein phosphorylation by extracellular signal-regulated kinase in single living cells

1 reference

12 December 2020

Use of a cAMP BRET sensor to characterize a novel regulation of cAMP by the sphingosine 1-phosphate/G13 pathway

1 reference

12 December 2020

Epidermal growth factor directs sex-specific steroid signaling through Src activation

1 reference

12 December 2020

The JNK signal transduction pathway

1 reference

12 December 2020

Beta-arrestins and cell signaling

1 reference

12 December 2020

Variation of linker length in ratiometric fluorescent sensor proteins allows rational tuning of Zn(II) affinity in the picomolar to femtomolar range

1 reference

12 December 2020

R-Ras regulates exocytosis by Rgl2/Rlf-mediated activation of RalA on endosomes.

1 reference

12 December 2020

Alpha4 integrins are type I cAMP-dependent protein kinase-anchoring proteins

1 reference

12 December 2020

Determining protein kinase substrate specificity by parallel solution-phase assay of large numbers of peptide substrates

1 reference

12 December 2020

Intramolecular and intermolecular interactions of protein kinase B define its activation in vivo

1 reference

12 December 2020

Monitoring ATM kinase activity in living cells

1 reference

12 December 2020

Spectroscopic and Structural Study of Proton and Halide Ion Cooperative Binding to GFP

1 reference

12 December 2020

Long-range Ca2 signaling from growth cone to soma mediates reversal of neuronal migration induced by slit-2.

1 reference

12 December 2020

Engineering and characterization of an enhanced fluorescent protein voltage sensor

1 reference

12 December 2020

Visualization of arginine influx into plant cells using a specific FRET-sensor

1 reference

12 December 2020

Design of fluorescence resonance energy transfer (FRET)-based cGMP indicators: a systematic approach

1 reference

12 December 2020

Far-field optical nanoscopy

1 reference

12 December 2020

Enhanced sensitivity of FRET-based protease sensors by redesign of the GFP dimerization interface

1 reference

12 December 2020

Involvement of the catalytic subunit of protein kinase A and of HA95 in pre-mRNA splicing

1 reference

12 December 2020

Single fluorescent protein-based Ca2 sensors with increased dynamic range.

1 reference

12 December 2020

Red-shifted Renilla reniformis luciferase variants for imaging in living subjects

1 reference

12 December 2020

AKAP79/150 anchoring of calcineurin controls neuronal L-type Ca2 channel activity and nuclear signaling

1 reference

12 December 2020

Oscillations and temporal signalling in cells.

1 reference

12 December 2020

Live-cell transforms between Ca2 transients and FRET responses for a troponin-C-based Ca2 sensor

1 reference

12 December 2020

Isoform-specific PKA dynamics revealed by dye-triggered aggregation and DAKAP1alpha-mediated localization in living cells

1 reference

12 December 2020

Nanosensor detection of an immunoregulatory tryptophan influx/kynurenine efflux cycle

1 reference

12 December 2020

Intramolecular fluorescence resonance energy transfer between fused autofluorescent proteins reveals rearrangements of the N- and C-terminal segments of the plasma membrane Ca2 pump involved in the activation

1 reference

12 December 2020

Bistability and oscillations in the Huang-Ferrell model of MAPK signaling

1 reference

12 December 2020

Live-cell molecular analysis of Akt activation reveals roles for activation loop phosphorylation

1 reference

12 December 2020

Ratiometric detection of Zn(II) using chelating fluorescent protein chimeras

1 reference

12 December 2020

Quantification of dynamic protein complexes using Renilla luciferase fragment complementation applied to protein kinase A activities in vivo

1 reference

12 December 2020

Calcium signaling in neuronal motility

1 reference

12 December 2020

Spatial and temporal regulation of focal adhesion kinase activity in living cells.

1 reference

12 December 2020

Portability of paddle motif function and pharmacology in voltage sensors

1 reference

12 December 2020

beta2-adrenergic receptor signaling and desensitization elucidated by quantitative modeling of real time cAMP dynamics

1 reference

12 December 2020

A tunable FRET circuit for engineering fluorescent biosensors

1 reference

12 December 2020

FRET by fluorescence polarization microscopy

1 reference

12 December 2020

Differential patterning of cGMP in vascular smooth muscle cells revealed by single GFP-linked biosensors

1 reference

12 December 2020

GLUT1 and GLUT9 as major contributors to glucose influx in HepG2 cells identified by a high sensitivity intramolecular FRET glucose sensor

1 reference

12 December 2020

Membrane phosphatidylserine regulates surface charge and protein localization

1 reference

12 December 2020

Mutational analysis of Deinococcus radiodurans bacteriophytochrome reveals key amino acids necessary for the photochromicity and proton exchange cycle of phytochromes

1 reference

12 December 2020

Engineering redox-sensitive linkers for genetically encoded FRET-based biosensors

1 reference

12 December 2020

A novel ZAP-70 dependent FRET based biosensor reveals kinase activity at both the immunological synapse and the antisynapse

1 reference

12 December 2020

Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors

1 reference

12 December 2020

Visualizing spatiotemporal dynamics of multicellular cell-cycle progression

1 reference

12 December 2020

Genetically encoded chloride indicator with improved sensitivity

1 reference

12 December 2020

Genetically encoded probe for fluorescence lifetime imaging of CaMKII activity

1 reference

12 December 2020

Design of a highly specific and noninvasive biosensor suitable for real-time in vivo imaging of mercury (II) uptake

1 reference

12 December 2020

Optical measurement of synaptic glutamate spillover and reuptake by linker optimized glutamate-sensitive fluorescent reporters

1 reference

12 December 2020

Simultaneous Recording of Multiple Cellular Events by FRET

1 reference

12 December 2020

A comparison of donor-acceptor pairs for genetically encoded FRET sensors: application to the Epac cAMP sensor as an example

1 reference

12 December 2020

Imaging of Rab5 activity identifies essential regulators for phagosome maturation

1 reference

12 December 2020

Quantitative analysis of pathways controlling extrinsic apoptosis in single cells

1 reference

12 December 2020

Fluorescent protein FRET pairs for ratiometric imaging of dual biosensors

1 reference

12 December 2020

A genetically encoded ratiometric sensor to measure extracellular pH in microdomains bounded by basolateral membranes of epithelial cells

1 reference

12 December 2020

Visualization of polarized membrane type 1 matrix metalloproteinase activity in live cells by fluorescence resonance energy transfer imaging

1 reference

12 December 2020

Protein kinase A effects of an expressed PRKAR1A mutation associated with aggressive tumors

1 reference

12 December 2020

Improving the photostability of bright monomeric orange and red fluorescent proteins

1 reference

12 December 2020

Midzone activation of aurora B in anaphase produces an intracellular phosphorylation gradient

1 reference

12 December 2020

Real-time imaging of the intracellular glutathione redox potential.

1 reference

12 December 2020

A fluorescence energy transfer-based mechanical stress sensor for specific proteins in situ

1 reference

12 December 2020

Cell shape and negative links in regulatory motifs together control spatial information flow in signaling networks

1 reference

12 December 2020

Visualization of phosphatase activity in living cells with a FRET-based calcineurin activity sensor

1 reference

12 December 2020

His-tags as Zn(II) binding motifs in a protein-based fluorescent sensor

1 reference

12 December 2020

Cell-based fluorescent indicator to visualize brain-derived neurotrophic factor secreted from living neurons

1 reference

12 December 2020

Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopy

1 reference

12 December 2020

Fluorescence resonance energy transfer sensors for quantitative monitoring of pentose and disaccharide accumulation in bacteria

1 reference

12 December 2020

Pharmacological characterization of membrane-expressed human trace amine-associated receptor 1 (TAAR1) by a bioluminescence resonance energy transfer cAMP biosensor

1 reference

12 December 2020

Novel genetically encoded biosensors using firefly luciferase

1 reference

12 December 2020

Bimolecular fluorescence complementation (BiFC) analysis as a probe of protein interactions in living cells

1 reference

12 December 2020

Engineering of a genetically encodable fluorescent voltage sensor exploiting fast Ci-VSP voltage-sensing movements

1 reference

12 December 2020

Fluorescence-based methods in the study of protein-protein interactions in living cells

1 reference

12 December 2020

Improving membrane voltage measurements using FRET with new fluorescent proteins

1 reference

12 December 2020

Development of a family of redox-sensitive green fluorescent protein indicators for use in relatively oxidizing subcellular environments

1 reference

12 December 2020

Superoxide flashes in single mitochondria

1 reference

12 December 2020

Rapid turnover rate of phosphoinositides at the front of migrating MDCK cells

1 reference

12 December 2020

Spatiotemporal analysis of differential Akt regulation in plasma membrane microdomains

1 reference

12 December 2020

The spatiotemporal pattern of Src activation at lipid rafts revealed by diffusion-corrected FRET imaging

1 reference

12 December 2020

Integrin-mediated protein kinase A activation at the leading edge of migrating cells

1 reference

12 December 2020

Crystal structure of Pseudomonas aeruginosa bacteriophytochrome: Photoconversion and signal transduction

1 reference

12 December 2020

Determination of hierarchical relationship of Src and Rac at subcellular locations with FRET biosensors.

1 reference

12 December 2020

Nuclear export signal consensus sequences defined using a localization-based yeast selection system

1 reference

12 December 2020

Mutational optimization of the coelenterazine-dependent luciferase from Renilla

1 reference

12 December 2020

Feedback loops shape cellular signals in space and time

1 reference

12 December 2020

Phosphorylation networks regulating JNK activity in diverse genetic backgrounds

1 reference

12 December 2020

Reporting neural activity with genetically encoded calcium indicators

1 reference

12 December 2020

Visualizing myosin-actin interaction with a genetically-encoded fluorescent strain sensor.

1 reference

12 December 2020

Design principles of biochemical oscillators

1 reference

12 December 2020

A genetically encoded fluorescent sensor of ERK activity

1 reference

12 December 2020

Modeling a snap-action, variable-delay switch controlling extrinsic cell death

1 reference

12 December 2020

Protein scaffolds in MAP kinase signalling

1 reference

12 December 2020

Tracing the silhouette of individual cells in S/G2/M phases with fluorescence

1 reference

12 December 2020

Calcium flickers steer cell migration.

1 reference

12 December 2020

A genetically encoded fluorescent reporter of ATP:ADP ratio

1 reference

12 December 2020

Monomeric fluorescent timers that change color from blue to red report on cellular trafficking

1 reference

12 December 2020

Sensing chromosome bi-orientation by spatial separation of aurora B kinase from kinetochore substrates

1 reference

12 December 2020

Use of Fluorescence Resonance Energy Transfer-based Biosensors for the Quantitative Analysis of Inositol 1,4,5-Trisphosphate Dynamics in Calcium Oscillations

1 reference

12 December 2020

A genetically encoded calcium indicator for chronic in vivo two-photon imaging

1 reference

12 December 2020

A bright and photostable photoconvertible fluorescent protein

1 reference

12 December 2020

mRuby, a bright monomeric red fluorescent protein for labeling of subcellular structures

1 reference

12 December 2020

pH-insensitive glucose indicators

1 reference

12 December 2020

Genetically encoded Förster resonance energy transfer sensors for the conformation of the Src family kinase Lck.

1 reference

12 December 2020

Genetically encoded FRET-based biosensors for multiparameter fluorescence imaging

1 reference

12 December 2020

The colorful journey of green fluorescent protein

1 reference

12 December 2020

Spectrally-resolved response properties of the three most advanced FRET based fluorescent protein voltage probes

1 reference

12 December 2020

Compartmentalized signalling: spatial regulation of cAMP by the action of compartmentalized phosphodiesterases.

1 reference

12 December 2020

Quantitative analysis of cell cycle phase durations and PC12 differentiation using fluorescent biosensors

1 reference

12 December 2020

Activation of CaMKII in single dendritic spines during long-term potentiation

1 reference

12 December 2020

Fluorescence changes reveal kinetic steps of muscarinic receptor-mediated modulation of phosphoinositides and Kv7.2/7.3 K channels

1 reference

12 December 2020

An ultramarine fluorescent protein with increased photostability and pH insensitivity

1 reference

12 December 2020

Genetically encoded sensors to elucidate spatial distribution of cellular zinc

1 reference

12 December 2020

A Golgi PKD activity reporter reveals a crucial role of PKD in nocodazole-induced Golgi dispersal

1 reference

12 December 2020

Mammalian expression of infrared fluorescent proteins engineered from a bacterial phytochrome

1 reference

12 December 2020

Cyclic GMP from the surrounding somatic cells regulates cyclic AMP and meiosis in the mouse oocyte

1 reference

12 December 2020

The chemical biology of protein phosphorylation

1 reference

12 December 2020

Super-resolution fluorescence microscopy

1 reference

12 December 2020

Red fluorescent protein pH biosensor to detect concentrative nucleoside transport

1 reference

12 December 2020

Dissecting activation of the PAK1 kinase at protrusions in living cells

1 reference

12 December 2020

The role of membrane microdomains in shaping beta2-adrenergic receptor-mediated cAMP dynamics

1 reference

12 December 2020

Persistent cAMP-signals triggered by internalized G-protein-coupled receptors

1 reference

12 December 2020

Sustained cyclic AMP production by parathyroid hormone receptor endocytosis.

1 reference

12 December 2020

Defining network topologies that can achieve biochemical adaptation.

1 reference

12 December 2020

Genetically encoded FRET sensors to monitor intracellular Zn2 homeostasis

1 reference

12 December 2020

Visualization of ATP levels inside single living cells with fluorescence resonance energy transfer-based genetically encoded indicators

1 reference

12 December 2020

Bimolecular fluorescence complementation analysis of inducible protein interactions: effects of factors affecting protein folding on fluorescent protein fragment association

1 reference

12 December 2020

Stimulus-specific distinctions in spatial and temporal dynamics of stress-activated protein kinase kinase kinases revealed by a fluorescence resonance energy transfer biosensor

1 reference

12 December 2020

Proximity-based protein thiol oxidation by H2O2-scavenging peroxidases

1 reference

12 December 2020

Visualization of molecular interactions using bimolecular fluorescence complementation analysis: characteristics of protein fragment complementation

1 reference

12 December 2020

Spatially distributed cell signalling

1 reference

12 December 2020

Real-time imaging of histone H4 hyperacetylation in living cells

1 reference

12 December 2020

Circular permutation of ligand-binding module improves dynamic range of genetically encoded FRET-based nanosensor

1 reference

12 December 2020

Splicing factor arginine/serine-rich 17A (SFRS17A) is an A-kinase anchoring protein that targets protein kinase A to splicing factor compartments

1 reference

12 December 2020

"cAMP sponge": a buffer for cyclic adenosine 3', 5'-monophosphate

1 reference

12 December 2020

Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators

1 reference

12 December 2020

Illuminating cell-cycle progression in the developing zebrafish embryo

1 reference

12 December 2020

Cracking the phosphatase code: docking interactions determine substrate specificity

1 reference

12 December 2020

An in vivo biosensor for neurotransmitter release and in situ receptor activity.

1 reference

12 December 2020

Distinct pools of cAMP centre on different isoforms of adenylyl cyclase in pituitary-derived GH3B6 cells.

1 reference

12 December 2020

Direct demonstration of discrete Ca2 microdomains associated with different isoforms of adenylyl cyclase

1 reference

12 December 2020

Fast, background-free, 3D super-resolution optical fluctuation imaging (SOFI).

1 reference

12 December 2020

Reversible dimerization of Aequorea victoria fluorescent proteins increases the dynamic range of FRET-based indicators

1 reference

12 December 2020

The scaffold protein Shoc2/SUR-8 accelerates the interaction of Ras and Raf.

1 reference

12 December 2020

Ras and calcium signaling pathways converge at Raf1 via the Shoc2 scaffold protein

1 reference

12 December 2020

H-independent glutamine transport in plant root tips

1 reference

12 December 2020

Dynamic copper(I) imaging in mammalian cells with a genetically encoded fluorescent copper(I) sensor.

1 reference

12 December 2020

Specificity and spatial dynamics of protein kinase A signaling organized by A-kinase-anchoring proteins

1 reference

12 December 2020

Differential regulation of protrusion and polarity by PI3K during neutrophil motility in live zebrafish

1 reference

12 December 2020

Blue fluorescent cGMP sensor for multiparameter fluorescence imaging

1 reference

12 December 2020

Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation.

1 reference

12 December 2020

Interaction with AKAP79 modifies the cellular pharmacology of PKC.

1 reference

12 December 2020

Simultaneous visualization of protumorigenic Src and MT1-MMP activities with fluorescence resonance energy transfer.

1 reference

12 December 2020

Visualization of JNK activity dynamics with a genetically encoded fluorescent biosensor

1 reference

12 December 2020

AKAP79 interacts with multiple adenylyl cyclase (AC) isoforms and scaffolds AC5 and -6 to alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA) receptors

1 reference

12 December 2020

A novel fluorescent timer based on bicistronic expression strategy in Caenorhabditis elegans.

1 reference

12 December 2020

AKAP79/150 interacts with AC8 and regulates Ca2 -dependent cAMP synthesis in pancreatic and neuronal systems

1 reference

12 December 2020

Progressive activation of CyclinB1-Cdk1 coordinates entry to mitosis

1 reference

12 December 2020

Type 4 phosphodiesterase plays different integrating roles in different cellular domains in pyramidal cortical neurons

1 reference

12 December 2020

Bioluminescence in the ocean: origins of biological, chemical, and ecological diversity

1 reference

12 December 2020

Imaging CREB activation in living cells.

1 reference

12 December 2020

Spatial organization of intracellular communication: insights from imaging

1 reference

12 December 2020

A novel fluorescent sensor protein for visualization of redox states in the cytoplasm and in peroxisomes.

1 reference

12 December 2020

Calcium transduces plasma membrane receptor signals to produce diacylglycerol at Golgi membranes

1 reference

12 December 2020

Simultaneous intracellular chloride and pH measurements using a GFP-based sensor

1 reference

12 December 2020

Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

1 reference

12 December 2020

Imaging brain electric signals with genetically targeted voltage-sensitive fluorescent proteins

1 reference

12 December 2020

The role of type 4 phosphodiesterases in generating microdomains of cAMP: large scale stochastic simulations

1 reference

12 December 2020

A Novel FRET-Based Biosensor for the Measurement of BCR-ABL Activity and Its Response to Drugs in Living Cells

1 reference

12 December 2020

Going deeper than microscopy: the optical imaging frontier in biology

1 reference

12 December 2020

Biophysical characterization of the fluorescent protein voltage probe VSFP2.3 based on the voltage-sensing domain of Ci-VSP

1 reference

12 December 2020

A genetically encoded sensor for H2O2 with expanded dynamic range.

1 reference

12 December 2020

Spontaneous network activity visualized by ultrasensitive Ca(2 ) indicators, yellow Cameleon-Nano

1 reference

12 December 2020

Activation of PDE2 and PDE5 by specific GAF ligands: delayed activation of PDE5.

1 reference

12 December 2020

Heterogeneity of phosphatidic acid levels and distribution at the plasma membrane in living cells as visualized by a Föster resonance energy transfer (FRET) biosensor

1 reference

12 December 2020

A glucose sensor protein for continuous glucose monitoring

1 reference

12 December 2020

Visualization of PKA activity in plasma membrane microdomains

1 reference

12 December 2020

A highly selective fluorescent probe for visualization of organic hydroperoxides in living cells

1 reference

12 December 2020

Signaling diversity of PKA achieved via a Ca2 -cAMP-PKA oscillatory circuit

1 reference

12 December 2020

Aurora B kinase activation requires survivin priming phosphorylation by PLK1

1 reference

12 December 2020

Visualizing dynamic cytoplasmic forces with a compliance-matched FRET sensor

1 reference

12 December 2020

The tightly regulated copper window in yeast

1 reference

12 December 2020

Computational models reduce complexity and accelerate insight into cardiac signaling networks

1 reference

12 December 2020

Dynamic regulation of the mitochondrial proton gradient during cytosolic calcium elevations

1 reference

12 December 2020

Drug-induced cell cycle modulation leading to cell-cycle arrest, nuclear mis-segregation, or endoreplication

1 reference

12 December 2020

Structure of a nanobody-stabilized active state of the β(2) adrenoceptor

1 reference

12 December 2020

Bacterial phytochromes: more than meets the light

1 reference

12 December 2020

Characterizing Ligand-Gated Ion Channel Receptors with Genetically Encoded Ca Sensors

1 reference

12 December 2020

Detection of mercury ion by infrared fluorescent protein and its hydrogel-based paper assay

1 reference

12 December 2020

CREB and the CRTC co-activators: sensors for hormonal and metabolic signals

1 reference

12 December 2020

Cyclic AMP-dependent protein kinase regulates the alternative splicing of tau exon 10: a mechanism involved in tau pathology of Alzheimer disease

1 reference

12 December 2020

Genetic visualization with an improved GCaMP calcium indicator reveals spatiotemporal activation of the spinal motor neurons in zebrafish

1 reference

12 December 2020

FRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cells

1 reference

12 December 2020

1 reference

12 December 2020

Luminescent Kinase Activity Biosensors Based on a Versatile Bimolecular Switch

1 reference

12 December 2020

Glucagon-like Peptide 1 Stimulates Post-translational Activation of Glucokinase in Pancreatic β Cells

1 reference

12 December 2020

An ion-insensitive cAMP biosensor for long term quantitative ratiometric fluorescence resonance energy transfer (FRET) measurements under variable physiological conditions

1 reference

12 December 2020

Genetically Encodable Fluorescent Biosensors for Tracking Signaling Dynamics in Living Cells

1 reference

12 December 2020

A fluorescent reporter of AMPK activity and cellular energy stress

1 reference

12 December 2020

Ca²⁺ regulation of mitochondrial ATP synthesis visualized at the single cell level

1 reference

12 December 2020

Measuring steady-state and dynamic endoplasmic reticulum and Golgi Zn 2 with genetically encoded sensors

1 reference

12 December 2020

Rapid development of genetically encoded FRET reporters.

1 reference

12 December 2020

Real-time imaging of histone H4K12-specific acetylation determines the modes of action of histone deacetylase and bromodomain inhibitors

1 reference

12 December 2020

Scaffold proteins: hubs for controlling the flow of cellular information

1 reference

12 December 2020

A mTurquoise-based cAMP sensor for both FLIM and ratiometric read-out has improved dynamic range

1 reference

12 December 2020

Bigger, better, faster: principles and models of AKAP anchoring protein signaling

1 reference

12 December 2020

Proteins move! Protein dynamics and long-range allostery in cell signaling

1 reference

12 December 2020

Development of a high-dynamic range, GFP-based FRET probe sensitive to oxidative microenvironments

1 reference

12 December 2020

Real-time visualization of heterotrimeric G protein Gq activation in living cells

1 reference

12 December 2020

Imaging intracellular pH in live cells with a genetically encoded red fluorescent protein sensor.

1 reference

12 December 2020

β-arrestin-mediated receptor trafficking and signal transduction

1 reference

12 December 2020

Calmodulin binding proteins provide domains of local Ca2 signaling in cardiac myocytes

1 reference

12 December 2020

Electrical Spiking in Escherichia coli Probed with a Fluorescent Voltage-Indicating Protein

1 reference

12 December 2020

Detection of focal adhesion kinase activation at membrane microdomains by fluorescence resonance energy transfer

1 reference

12 December 2020

Spatiotemporally Regulated Protein Kinase A Activity Is a Critical Regulator of Growth Factor-Stimulated Extracellular Signal-Regulated Kinase Signaling in PC12 Cells

1 reference

12 December 2020

pHluorin2: an enhanced, ratiometric, pH-sensitive green florescent protein

1 reference

12 December 2020

Greatly enhanced detection of a volatile ligand at femtomolar levels using bioluminescence resonance energy transfer (BRET).

1 reference

12 December 2020

PI3K/Akt signaling requires spatial compartmentalization in plasma membrane microdomains

1 reference

12 December 2020

G-PKDrep-live, a genetically encoded FRET reporter to measure PKD activity at the trans-Golgi-network

1 reference

12 December 2020

An expanded palette of genetically encoded Ca²⁺ indicators

1 reference

12 December 2020

Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes

1 reference

12 December 2020

Design and application of a class of sensors to monitor Ca2 dynamics in high Ca2 concentration cellular compartments

1 reference

12 December 2020

Structural flexibility of the G alpha s alpha-helical domain in the beta2-adrenoceptor Gs complex

1 reference

12 December 2020

Information transduction capacity of noisy biochemical signaling networks

1 reference

12 December 2020

A Luminescent Biosensor with Increased Dynamic Range for Intracellular cAMP

1 reference

12 December 2020

Development of an optimized backbone of FRET biosensors for kinases and GTPases

1 reference

12 December 2020

Imaging cytosolic NADH-NAD( ) redox state with a genetically encoded fluorescent biosensor

1 reference

12 December 2020

Genetically encoded fluorescent sensors for intracellular NADH detection

1 reference

12 December 2020

Microtubule affinity regulating kinase activity in living neurons was examined by a genetically encoded fluorescence resonance energy transfer/fluorescence lifetime imaging-based biosensor: inhibitors with therapeutic potential

1 reference

12 December 2020

Reengineering of a fluorescent zinc sensor protein yields the first genetically encoded cadmium probe

1 reference

12 December 2020

A genetically encoded, high-signal-to-noise maltose sensor

1 reference

12 December 2020

Imaging the coordination of multiple signalling activities in living cells

1 reference

12 December 2020

Structure of the Escherichia coli phosphonate binding protein PhnD and rationally optimized phosphonate biosensors

1 reference

12 December 2020

Förster resonance energy transfer-based biosensors for multiparameter ratiometric imaging of Ca2 dynamics and caspase-3 activity in single cells

1 reference

12 December 2020

Ratiometric fluorescence imaging of dual bio-molecular events in single living cells using a new FRET pair mVenus/mKOκ-based biosensor and a single fluorescent protein biosensor

1 reference

12 December 2020

Assessment of cellular mechanisms contributing to cAMP compartmentalization in pulmonary microvascular endothelial cells.

1 reference

12 December 2020

Optical recording of action potentials in mammalian neurons using a microbial rhodopsin

1 reference

12 December 2020

Systematic control of protein interaction using a modular ER/K α-helix linker

1 reference

12 December 2020

Cyclic AMP-Dependent Protein Kinase A Regulates the Alternative Splicing of CaMKIIδ

1 reference

12 December 2020

Gating of the MlotiK1 potassium channel involves large rearrangements of the cyclic nucleotide-binding domains

1 reference

12 December 2020

Early and late calcium waves during wound healing in corneal endothelial cells

1 reference

12 December 2020

Biased excitable networks: how cells direct motion in response to gradients.

1 reference

12 December 2020

Engineering genetically encoded nanosensors for real-time in vivo measurements of citrate concentrations

1 reference

12 December 2020

Structural biology of the chromodomain: form and function

1 reference

12 December 2020

A high-throughput FRET-based assay for determination of Atg4 activity

1 reference

12 December 2020

Balanced interactions of calcineurin with AKAP79 regulate Ca2 –calcineurin–NFAT signaling

1 reference

12 December 2020

Subcellular location of PKA controls striatal plasticity: stochastic simulations in spiny dendrites

1 reference

12 December 2020

Regulation of nuclear PKA revealed by spatiotemporal manipulation of cyclic AMP.

1 reference

12 December 2020

Orientation-based FRET sensor for real-time imaging of cellular forces

1 reference

12 December 2020

Live imaging of intra- and extracellular pH in plants using pHusion, a novel genetically encoded biosensor

1 reference

12 December 2020

Structure-guided evolution of cyan fluorescent proteins towards a quantum yield of 93%.

1 reference

12 December 2020

Real-time determination of intracellular oxygen in bacteria using a genetically encoded FRET-based biosensor

1 reference

12 December 2020

Photoacoustic tomography: in vivo imaging from organelles to organs

1 reference

12 December 2020

A fluorogenic red fluorescent protein heterodimer

1 reference

12 December 2020

Cytoplasmic calcium buffering

1 reference

12 December 2020

Spatial modeling of cell signaling networks

1 reference

12 December 2020

An orange fluorescent protein with a large Stokes shift for single-excitation multicolor FCCS and FRET imaging

1 reference

12 December 2020

Nanodomain Ca²⁺ of Ca²⁺ channels detected by a tethered genetically encoded Ca²⁺ sensor

1 reference

12 December 2020

Mechanism of voltage gating in potassium channels

1 reference

12 December 2020

Designing photoswitchable peptides using the AsLOV2 domain

1 reference

12 December 2020

Elementary Ca2 signals through endothelial TRPV4 channels regulate vascular function.

1 reference

12 December 2020

How cells process information: quantification of spatiotemporal signaling dynamics

1 reference

12 December 2020

The human phosphatase interactome: An intricate family portrait

1 reference

12 December 2020

Long-range Ca2 waves transmit brain-damage signals to microglia

1 reference

12 December 2020

Genetically encoded fluorescent voltage sensors using the voltage-sensing domain of Nematostella and Danio phosphatases exhibit fast kinetics

1 reference

12 December 2020

pHTomato, a red, genetically encoded indicator that enables multiplex interrogation of synaptic activity

1 reference

12 December 2020

Reaction-based genetically encoded fluorescent hydrogen sulfide sensors

1 reference

12 December 2020

Cooperative activation of PI3K by Ras and Rho family small GTPases

1 reference

12 December 2020

Widely accessible method for superresolution fluorescence imaging of living systems

1 reference

12 December 2020

Visualization of glutamine transporter activities in living cells using genetically encoded glutamine sensors

1 reference

12 December 2020

Tandem fluorescent protein timers for in vivo analysis of protein dynamics

1 reference

12 December 2020

An improved genetically encoded red fluorescent Ca2 indicator for detecting optically evoked action potentials

1 reference

12 December 2020

Imaging neural circuit dynamics with a voltage-sensitive fluorescent protein.

1 reference

12 December 2020

Structural basis for efficient chromophore communication and energy transfer in a constructed didomain protein scaffold

1 reference

12 December 2020

Effect of insulin analogues on insulin/IGF1 hybrid receptors: increased activation by glargine but not by its metabolites M1 and M2

1 reference

12 December 2020

New sensors for quantitative measurement of mitochondrial Zn(2 )

1 reference

12 December 2020

The application of information theory to biochemical signaling systems

1 reference

12 December 2020

Engineered luciferase reporter from a deep sea shrimp utilizing a novel imidazopyrazinone substrate

1 reference

12 December 2020

PKA and PDE4D3 anchoring to AKAP9 provides distinct regulation of cAMP signals at the centrosome

1 reference

12 December 2020

A selective fluorescent probe for carbon monoxide imaging in living cells

1 reference

12 December 2020

Transfer of Kv3.1 voltage sensor features to the isolated Ci-VSP voltage-sensing domain

1 reference

12 December 2020

Histone phosphorylation: a chromatin modification involved in diverse nuclear events

1 reference

12 December 2020

Unnatural amino acid mutagenesis of fluorescent proteins

1 reference

12 December 2020

Single action potentials and subthreshold electrical events imaged in neurons with a fluorescent protein voltage probe.

1 reference

12 December 2020

Improving FRET dynamic range with bright green and red fluorescent proteins

1 reference

12 December 2020

A fluorescent, genetically-encoded voltage probe capable of resolving action potentials

1 reference

12 December 2020

Quantitative live imaging of endogenous DNA replication in mammalian cells

1 reference

12 December 2020

In vivo FRET imaging revealed a regulatory role of RanGTP in kinetochore-microtubule attachments via Aurora B kinase.

1 reference

12 December 2020

Spatiotemporal correlations between cytosolic and mitochondrial Ca(2 ) signals using a novel red-shifted mitochondrial targeted cameleon

1 reference

12 December 2020

Optimization of a GCaMP Calcium Indicator for Neural Activity Imaging

1 reference

12 December 2020

Creating order from chaos: cellular regulation by kinase anchoring

1 reference

12 December 2020

The temporal pattern of stimulation determines the extent and duration of MAPK activation in a Caenorhabditis elegans sensory neuron

1 reference

12 December 2020

Advantages of substituting bioluminescence for fluorescence in a resonance energy transfer-based periplasmic binding protein biosensor

1 reference

12 December 2020

Enhanced-acceptor fluorescence-based single cell ATP biosensor monitors ATP in heterogeneous cancer populations in real time

1 reference

12 December 2020

Localized calcineurin confers Ca2 -dependent inactivation on neuronal L-type Ca2 channels

1 reference

12 December 2020

Spatial and temporal analysis of NADPH oxidase-generated hydrogen peroxide signals by novel fluorescent reporter proteins

1 reference

12 December 2020

Multiplexed visualization of dynamic signaling networks using genetically encoded fluorescent protein-based biosensors

1 reference

12 December 2020

An improved short-lived fluorescent protein transcriptional reporter for Saccharomyces cerevisiae

1 reference

12 December 2020

Visualization of cell cycle in mouse embryos with Fucci2 reporter directed by Rosa26 promoter

1 reference

12 December 2020

Luminescent proteins for high-speed single-cell and whole-body imaging

1 reference

12 December 2020

Genetically encoded green fluorescent Ca2 indicators with improved detectability for neuronal Ca2 signals

1 reference

12 December 2020

HyPer-3: a genetically encoded H(2)O(2) probe with improved performance for ratiometric and fluorescence lifetime imaging.

1 reference

12 December 2020

Highlightable Ca2 indicators for live cell imaging

1 reference

12 December 2020

Extracellular calcium influx activates adenylate cyclase 1 and potentiates insulin secretion in MIN6 cells

1 reference

12 December 2020

An optimized fluorescent probe for visualizing glutamate neurotransmission

1 reference

12 December 2020

Fluorescent proteins: shine on, you crazy diamond.

1 reference

12 December 2020

An improved Ras sensor for highly sensitive and quantitative FRET-FLIM imaging

1 reference

12 December 2020

The role of transcription-independent damage signals in the initiation of epithelial wound healing

1 reference

12 December 2020

Improved orange and red Ca²± indicators and photophysical considerations for optogenetic applications

1 reference

12 December 2020

Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics

1 reference

12 December 2020

A genetically encoded FRET lactate sensor and its use to detect the Warburg effect in single cancer cells

1 reference

12 December 2020

Conformational biosensors reveal GPCR signalling from endosomes.

1 reference

12 December 2020

Monitoring of dual bio-molecular events using FRET biosensors based on mTagBFP/sfGFP and mVenus/mKOκ fluorescent protein pairs

1 reference

12 December 2020

A bright monomeric green fluorescent protein derived from Branchiostoma lanceolatum

1 reference

12 December 2020

Oscillations of sub-membrane ATP in glucose-stimulated beta cells depend on negative feedback from Ca(2 ).

1 reference

12 December 2020

Dictyostelium Ric8 is a nonreceptor guanine exchange factor for heterotrimeric G proteins and is important for development and chemotaxis

1 reference

12 December 2020

Ultrasensitive response motifs: basic amplifiers in molecular signalling networks

1 reference

12 December 2020

Detection of G protein-selective G protein-coupled receptor (GPCR) conformations in live cells

1 reference

12 December 2020

Dimerization-dependent green and yellow fluorescent proteins

1 reference

12 December 2020

ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

1 reference

12 December 2020

The small GTPase HRas shapes local PI3K signals through positive feedback and regulates persistent membrane extension in migrating fibroblasts

1 reference

12 December 2020

APC(CDH1) targets MgcRacGAP for destruction in the late M phase

1 reference

12 December 2020

Signal integration by mTORC1 coordinates nutrient input with biosynthetic output.

1 reference

12 December 2020

Near-infrared fluorescent proteins for multicolor in vivo imaging

1 reference

12 December 2020

Differential G protein subunit expression by prostate cancer cells and their interaction with CXCR5

1 reference

12 December 2020

Recombinant probes for visualizing endogenous synaptic proteins in living neurons

1 reference

12 December 2020

Very long-term memories may be stored in the pattern of holes in the perineuronal net.

1 reference

12 December 2020

Improved detection of electrical activity with a voltage probe based on a voltage-sensing phosphatase

1 reference

12 December 2020

Enhanced Archaerhodopsin Fluorescent Protein Voltage Indicators

1 reference

12 December 2020

Fluorescent sensors reporting the activity of ammonium transceptors in live cells.

1 reference

12 December 2020

Ultrasensitive fluorescent proteins for imaging neuronal activity

1 reference

12 December 2020

In vivo fluorescent adenosine 5'-triphosphate (ATP) imaging of Drosophila melanogaster and Caenorhabditis elegans by using a genetically encoded fluorescent ATP biosensor optimized for low temperatures.

1 reference

12 December 2020

A versatile toolkit to produce sensitive FRET biosensors to visualize signaling in time and space

1 reference

12 December 2020

The inner and outer compartments of mitochondria are sites of distinct cAMP/PKA signaling dynamics

1 reference

12 December 2020

REV, A BRET-Based Sensor of ERK Activity

1 reference

12 December 2020

Theoretical principles and practical considerations for fluorescence resonance energy transfer microscopy

1 reference

12 December 2020

Robust red FRET sensors using self-associating fluorescent domains

1 reference

12 December 2020

Tuning local calcium availability: cell-type-specific immobile calcium buffer capacity in hippocampal neurons.

1 reference

12 December 2020

Integrating fluorescent biosensor data using computational models

1 reference

12 December 2020

Fluorescent proteins for live-cell imaging with super-resolution

1 reference

12 December 2020

Adrenaline-activated structure of β2-adrenoceptor stabilized by an engineered nanobody

1 reference

12 December 2020

Genetically encoded fluorescent probe for the selective detection of peroxynitrite.

1 reference

12 December 2020

Improved genetically-encoded, FlincG-type fluorescent biosensors for neural cGMP imaging.

1 reference

12 December 2020

The proliferation-quiescence decision is controlled by a bifurcation in CDK2 activity at mitotic exit

1 reference

12 December 2020

A new protein-protein interaction sensor based on tripartite split-GFP association

1 reference

12 December 2020

Imaging energy status in live cells with a fluorescent biosensor of the intracellular ATP-to-ADP ratio

1 reference

12 December 2020

Direct measurements of oscillatory glycolysis in pancreatic islet β-cells using novel fluorescence resonance energy transfer (FRET) biosensors for pyruvate kinase M2 activity

1 reference

12 December 2020

Visualization of Synaptic Inhibition with an Optogenetic Sensor Developed by Cell-Free Protein Engineering Automation

1 reference

12 December 2020

Stochastic ERK activation induced by noise and cell-to-cell propagation regulates cell density-dependent proliferation

1 reference

12 December 2020

Highly efficient CRISPR/Cas9-mediated knock-in in zebrafish by homology-independent DNA repair.

1 reference

12 December 2020

Intrinsic disorder within an AKAP-protein kinase A complex guides local substrate phosphorylation

1 reference

12 December 2020

Development of a FRET biosensor with high specificity for Akt.

1 reference

12 December 2020

A RhoC biosensor reveals differences in the activation kinetics of RhoA and RhoC in migrating cells

1 reference

12 December 2020

A single fluorescent protein-based sensor for in vivo 2-oxogluatarate detection in cell.

1 reference

12 December 2020

Activation and allosteric modulation of a muscarinic acetylcholine receptor

1 reference

12 December 2020

Optimization of a genetically encoded biosensor for cyclin B1-cyclin dependent kinase 1.

1 reference

12 December 2020

Genetically encoded fluorescent indicator for imaging NAD( )/NADH ratio changes in different cellular compartments

1 reference

12 December 2020

Scaffold state switching amplifies, accelerates, and insulates protein kinase C signaling

1 reference

12 December 2020

Fluorescent protein voltage probes derived from ArcLight that respond to membrane voltage changes with fast kinetics

1 reference

12 December 2020

Genetically encoded fluorescent probe to visualize intracellular phosphatidylinositol 3,5-bisphosphate localization and dynamics

1 reference

12 December 2020

Single-fluorophore biosensors based on conformation-sensitive GFP variants.

1 reference

12 December 2020

CRIS-a novel cAMP-binding protein controlling spermiogenesis and the development of flagellar bending

1 reference

12 December 2020

In vivo three-photon microscopy of subcortical structures within an intact mouse brain

1 reference

12 December 2020

Mechanisms of cyclic AMP compartmentation revealed by computational models

1 reference

12 December 2020

Where is mTOR and what is it doing there?

1 reference

12 December 2020

Optimized ratiometric calcium sensors for functional in vivo imaging of neurons and T lymphocytes

1 reference

12 December 2020

Isoform-selective disruption of AKAP-localized PKA using hydrocarbon stapled peptides

1 reference

12 December 2020

Optimization of ERK activity biosensors for both ratiometric and lifetime FRET measurements

1 reference

12 December 2020

Imaging mitochondrial flux in single cells with a FRET sensor for pyruvate

1 reference

12 December 2020

A tunable fluorescent timer method for imaging spatial-temporal protein dynamics using light-driven photoconvertible protein

1 reference

12 December 2020

Data-driven modeling reconciles kinetics of ERK phosphorylation, localization, and activity states

1 reference

12 December 2020

GAP, an aequorin-based fluorescent indicator for imaging Ca2 in organelles

1 reference

12 December 2020

Activity-driven local ATP synthesis is required for synaptic function.

1 reference

12 December 2020

CRISPR-Cas systems for editing, regulating and targeting genomes

1 reference

12 December 2020

Light-mediated kinetic control reveals the temporal effect of the Raf/MEK/ERK pathway in PC12 cell neurite outgrowth

1 reference

12 December 2020

Imaging neural spiking in brain tissue using FRET-opsin protein voltage sensors.

1 reference

12 December 2020

High-fidelity optical reporting of neuronal electrical activity with an ultrafast fluorescent voltage sensor

1 reference

12 December 2020

A PKA activity sensor for quantitative analysis of endogenous GPCR signaling via 2-photon FRET-FLIM imaging

1 reference

12 December 2020

Recent progress in generating intracellular functional antibody fragments to target and trace cellular components in living cells

1 reference

12 December 2020

A new genetically encoded single-chain biosensor for Cdc42 based on FRET, useful for live-cell imaging

1 reference

12 December 2020

An improved monomeric infrared fluorescent protein for neuronal and tumour brain imaging

1 reference

12 December 2020

Chronological analysis with fluorescent timer reveals unique features of newly generated β-cells.

1 reference

12 December 2020

AKAP-anchored PKA maintains neuronal L-type calcium channel activity and NFAT transcriptional signaling.

1 reference

12 December 2020

Junctional cleft [Ca²⁺]i measurements using novel cleft-targeted Ca²⁺ sensors

1 reference

12 December 2020

Fluorescent labelling of the actin cytoskeleton in plants using a cameloid antibody

1 reference

12 December 2020

A genetically-encoded YFP sensor with enhanced chloride sensitivity, photostability and reduced ph interference demonstrates augmented transmembrane chloride movement by gerbil prestin (SLC26a5).

1 reference

12 December 2020

Imaging intraorganellar Ca2 at subcellular resolution using CEPIA

1 reference

12 December 2020

High-sensitivity measurements of multiple kinase activities in live single cells

1 reference

12 December 2020

All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins

1 reference

12 December 2020

Genetically-encoded yellow fluorescent cAMP indicator with an expanded dynamic range for dual-color imaging

1 reference

12 December 2020

Photoactivated localization microscopy with bimolecular fluorescence complementation (BiFC-PALM) for nanoscale imaging of protein-protein interactions in cells

1 reference

12 December 2020

A biosensor to monitor dynamic regulation and function of tumour suppressor PTEN in living cells

1 reference

12 December 2020

Super-resolution imaging and tracking of protein-protein interactions in sub-diffraction cellular space

1 reference

12 December 2020

Visualization of arrestin recruitment by a G-protein-coupled receptor

1 reference

12 December 2020

Phosphorylation of Dok1 by Abl family kinases inhibits CrkI transforming activity

1 reference

12 December 2020

Calmodulin-controlled spatial decoding of oscillatory Ca2 signals by calcineurin

1 reference

12 December 2020

Harnessing the unique structural properties of isolated α-helices.

1 reference

12 December 2020

Bright and fast multicoloured voltage reporters via electrochromic FRET

1 reference

12 December 2020

A highly responsive and selective fluorescent probe for imaging physiological hydrogen sulfide

1 reference

12 December 2020

Red fluorescent genetically encoded Ca2 indicators for use in mitochondria and endoplasmic reticulum

1 reference

12 December 2020

Toward a systems-level view of dynamic phosphorylation networks

1 reference

12 December 2020

Archaerhodopsin variants with enhanced voltage-sensitive fluorescence in mammalian and Caenorhabditis elegans neurons

1 reference

12 December 2020

Diversity in ATP concentrations in a single bacterial cell population revealed by quantitative single-cell imaging

1 reference

12 December 2020

Exploration of genetically encoded voltage indicators based on a chimeric voltage sensing domain

1 reference

12 December 2020

Red fluorescent genetically encoded indicator for intracellular hydrogen peroxide

1 reference

12 December 2020

Cell-based reporters reveal in vivo dynamics of dopamine and norepinephrine release in murine cortex

1 reference

12 December 2020

Superresolution imaging reveals structural features of EB1 in microtubule plus-end tracking.

1 reference

12 December 2020

A long Stokes shift red fluorescent Ca2 indicator protein for two-photon and ratiometric imaging

1 reference

12 December 2020

pHuji, a pH-sensitive red fluorescent protein for imaging of exo- and endocytosis

1 reference

12 December 2020

Rational design of a high-affinity, fast, red calcium indicator R-CaMP2.

1 reference

12 December 2020

Genome editing. The new frontier of genome engineering with CRISPR-Cas9

1 reference

12 December 2020

TALEN/CRISPR-mediated eGFP knock-in add-on at the OCT4 locus does not impact differentiation of human embryonic stem cells towards endoderm

1 reference

12 December 2020

Systems biology. Accurate information transmission through dynamic biochemical signaling networks

1 reference

12 December 2020

Combinatorial mutagenesis of the voltage-sensing domain enables the optical resolution of action potentials firing at 60 Hz by a genetically encoded fluorescent sensor of membrane potential.

1 reference

12 December 2020

Monitoring interactions and dynamics of endogenous beta-catenin with intracellular nanobodies in living cells

1 reference

12 December 2020

Ratiometric biosensors based on dimerization-dependent fluorescent protein exchange

1 reference

12 December 2020

Mechanosensitive store-operated calcium entry regulates the formation of cell polarity.

1 reference

12 December 2020

Monitoring redox dynamics in living cells with a redox-sensitive red fluorescent protein

1 reference

12 December 2020

Neural circuits. Labeling of active neural circuits in vivo with designed calcium integrators

1 reference

12 December 2020

Dendritic geometry shapes neuronal cAMP signalling to the nucleus

1 reference

12 December 2020

Natural photoreceptors as a source of fluorescent proteins, biosensors, and optogenetic tools.

1 reference

12 December 2020

Rationally designed fluorogenic protease reporter visualizes spatiotemporal dynamics of apoptosis in vivo

1 reference

12 December 2020

Role for Tyrosine Phosphorylation of A-kinase Anchoring Protein 8 (AKAP8) in Its Dissociation from Chromatin and the Nuclear Matrix

1 reference

12 December 2020

Dynamic Visualization of mTORC1 Activity in Living Cells.

1 reference

12 December 2020

Signalling scaffolds and local organization of cellular behaviour

1 reference

12 December 2020

Polarized activities of AMPK and BRSK in primary hippocampal neurons

1 reference

12 December 2020

Expanded palette of Nano-lanterns for real-time multicolor luminescence imaging.

1 reference

12 December 2020

A Genetically Encoded FRET Sensor for Intracellular Heme

1 reference

12 December 2020

In vivo cell-cycle profiling in xenograft tumors by quantitative intravital microscopy

1 reference

12 December 2020

Live-Cell STED Microscopy with Genetically Encoded Biosensor.

1 reference

12 December 2020

Fourth-generation epac-based FRET sensors for cAMP feature exceptional brightness, photostability and dynamic range: characterization of dedicated sensors for FLIM, for ratiometry and with high affinity

1 reference

12 December 2020

Compartmentalized AMPK signaling illuminated by genetically encoded molecular sensors and actuators

1 reference

12 December 2020

CRISPR/Cas9-mediated endogenous protein tagging for RESOLFT super-resolution microscopy of living human cells

1 reference

12 December 2020

Measurement of inositol 1,4,5-trisphosphate in living cells using an improved set of resonance energy transfer-based biosensors

1 reference

12 December 2020

A Genetically Encoded FRET Probe to Detect Intranucleosomal Histone H3K9 or H3K14 Acetylation Using BRD4, a BET Family Member

1 reference

12 December 2020

SoNar, a Highly Responsive NAD /NADH Sensor, Allows High-Throughput Metabolic Screening of Anti-tumor Agents

1 reference

12 December 2020

Akt signaling dynamics in individual cells

1 reference

12 December 2020

Novel fluorescence resonance energy transfer-based reporter reveals differential calcineurin activation in neonatal and adult cardiomyocytes.

1 reference

12 December 2020

A naturally monomeric infrared fluorescent protein for protein labeling in vivo.

1 reference

12 December 2020

Kinase-interacting substrate screening is a novel method to identify kinase substrates

1 reference

12 December 2020

Homo-FRET Based Biosensors and Their Application to Multiplexed Imaging of Signalling Events in Live Cells.

1 reference

12 December 2020

eZinCh-2: A Versatile, Genetically Encoded FRET Sensor for Cytosolic and Intraorganelle Zn(2 ) Imaging.

1 reference

12 December 2020

Linker length and fusion site composition improve the optical signal of genetically encoded fluorescent voltage sensors

1 reference

12 December 2020

FRET sensor-based quantification of intracellular trehalose in mammalian cells.

1 reference

12 December 2020

Dynamic single cell measurements of kinase activity by synthetic kinase activity relocation sensors

1 reference

12 December 2020

Structural insights into µ-opioid receptor activation

1 reference

12 December 2020

An Isoform-Specific Myristylation Switch Targets Type II PKA Holoenzymes to Membranes

1 reference

12 December 2020

Real-time analysis of epithelial-mesenchymal transition using fluorescent single-domain antibodies

1 reference

12 December 2020

Receptor Level Mechanisms Are Required for Epidermal Growth Factor (EGF)-stimulated Extracellular Signal-regulated Kinase (ERK) Activity Pulses

1 reference

12 December 2020

A practical method for monitoring FRET-based biosensors in living animals using two-photon microscopy

1 reference

12 December 2020

Oscillation of p38 activity controls efficient pro-inflammatory gene expression.

1 reference

12 December 2020

Plasma membrane restricted RhoGEF activity is sufficient for RhoA-mediated actin polymerization

1 reference

12 December 2020

SrGAP2-Dependent Integration of Membrane Geometry and Slit-Robo-Repulsive Cues Regulates Fibroblast Contact Inhibition of Locomotion.

1 reference

12 December 2020

Paracrine communication maximizes cellular response fidelity in wound signaling

1 reference

12 December 2020

A Low Affinity GCaMP3 Variant (GCaMPer) for Imaging the Endoplasmic Reticulum Calcium Store

1 reference

12 December 2020

A dark green fluorescent protein as an acceptor for measurement of Förster resonance energy transfer.

1 reference

12 December 2020

Generation of an alpaca-derived nanobody recognizing γ-H2AX

1 reference

12 December 2020

Extracellular rigidity sensing by talin isoform-specific mechanical linkages

1 reference

12 December 2020

A genetically encoded biosensor for in vitro and in vivo detection of NADP(.).

1 reference

12 December 2020

Fast-Response Calmodulin-Based Fluorescent Indicators Reveal Rapid Intracellular Calcium Dynamics

1 reference

12 December 2020

Visualization of Compartmentalized Kinase Activity Dynamics Using Adaptable BimKARs

1 reference

12 December 2020

Live Imaging of Calcium Dynamics during Axon Degeneration Reveals Two Functionally Distinct Phases of Calcium Influx.

1 reference

12 December 2020

High-speed recording of neural spikes in awake mice and flies with a fluorescent voltage sensor

1 reference

12 December 2020

Developing Fast Fluorescent Protein Voltage Sensors by Optimizing FRET Interactions

1 reference

12 December 2020

A novel family of fluorescent hypoxia sensors reveal strong heterogeneity in tumor hypoxia at the cellular level

1 reference

12 December 2020

Single-molecule fluorimetry and gating currents inspire an improved optical voltage indicator

1 reference

12 December 2020

Incomplete proteasomal degradation of green fluorescent proteins in the context of tandem fluorescent protein timers

1 reference

12 December 2020

Frequency modulation of ERK activation dynamics rewires cell fate

1 reference

12 December 2020

New DAG and cAMP Sensors Optimized for Live-Cell Assays in Automated Laboratories

1 reference

12 December 2020

Locally excitable Cdc42 signals steer cells during chemotaxis.

1 reference

12 December 2020

BRET-monitoring of the dynamic changes of inositol lipid pools in living cells reveals a PKC-dependent PtdIns4P increase upon EGF and M3 receptor activation

1 reference

12 December 2020

Signaling pathway models as biomarkers: Patient-specific simulations of JNK activity predict the survival of neuroblastoma patients

1 reference

12 December 2020

Regulation of Glucokinase by Intracellular Calcium Levels in Pancreatic β Cells

1 reference

12 December 2020

RefSOFI for Mapping Nanoscale Organization of Protein-Protein Interactions in Living Cells.

1 reference

12 December 2020

Development of redox-sensitive red fluorescent proteins for imaging redox dynamics in cellular compartments

1 reference

12 December 2020

Bistability of a coupled Aurora B kinase-phosphatase system in cell division

1 reference

12 December 2020

FRET biosensors reveal AKAP-mediated shaping of subcellular PKA activity and a novel mode of Ca(2 )/PKA crosstalk

1 reference

12 December 2020

Mechanisms Restricting Diffusion of Intracellular cAMP.

1 reference

12 December 2020

A New Generation of FRET Sensors for Robust Measurement of Gαi1, Gαi2 and Gαi3 Activation Kinetics in Single Cells

1 reference

12 December 2020

Replication-Competent Influenza A and B Viruses Expressing a Fluorescent Dynamic Timer Protein for In Vitro and In Vivo Studies

1 reference

12 December 2020

Spider Silk Peptide Is a Compact, Linear Nanospring Ideal for Intracellular Tension Sensing

1 reference

12 December 2020

Genetically encoded far-red fluorescent sensors for caspase-3 activity.

1 reference

12 December 2020

Apollo-NADP( ): a spectrally tunable family of genetically encoded sensors for NADP( ).

1 reference

12 December 2020

A Bright and Fast Red Fluorescent Protein Voltage Indicator That Reports Neuronal Activity in Organotypic Brain Slices

1 reference

12 December 2020

Spatio-temporal co-ordination of RhoA, Rac1 and Cdc42 activation during prototypical edge protrusion and retraction dynamics

1 reference

12 December 2020

Engineering Dark Chromoprotein Reporters for Photoacoustic Microscopy and FRET Imaging.

1 reference

12 December 2020

Resonance Energy Transfer-Based Approaches to Study GPCRs

1 reference

12 December 2020

A New Nanobody-Based Biosensor to Study Endogenous PARP1 In Vitro and in Live Human Cells

1 reference

12 December 2020

SnapShot: Timescales in Cell Biology

1 reference

12 December 2020

Versatile protein tagging in cells with split fluorescent protein

1 reference

12 December 2020

A novel biosensor to study cAMP dynamics in cilia and flagella

1 reference

12 December 2020

Sensitive red protein calcium indicators for imaging neural activity

1 reference

12 December 2020

Real-time monitoring of basal H2O2 levels with peroxiredoxin-based probes.

1 reference

12 December 2020

Intracellular tortuosity underlies slow cAMP diffusion in adult ventricular myocytes.

1 reference

12 December 2020

Protein Scaffolds Control Localized Protein Kinase Cζ Activity

1 reference

12 December 2020

High-Throughput, High-Resolution Mapping of Protein Localization in Mammalian Brain by In Vivo Genome Editing.

1 reference

12 December 2020

Nontrivial Effect of the Color-Exchange of a Donor/Acceptor Pair in the Engineering of Förster Resonance Energy Transfer (FRET)-Based Indicators

1 reference

12 December 2020

A bright cyan-excitable orange fluorescent protein facilitates dual-emission microscopy and enhances bioluminescence imaging in vivo

1 reference

12 December 2020

Multiplexed Fluorescence Imaging of ERK and Akt Activities and Cell-cycle Progression.

1 reference

12 December 2020

Heme dynamics and trafficking factors revealed by genetically encoded fluorescent heme sensors.

1 reference

12 December 2020

Subcellular Imaging of Voltage and Calcium Signals Reveals Neural Processing In Vivo

1 reference

12 December 2020

GFP-Aequorin Protein Sensor for Ex Vivo and In Vivo Imaging of Ca(2 ) Dynamics in High-Ca(2 ) Organelles

1 reference

12 December 2020

Biosensor reveals multiple sources for mitochondrial NAD⁺.

1 reference

12 December 2020

A Computational Modeling and Simulation Approach to Investigate Mechanisms of Subcellular cAMP Compartmentation.

1 reference

12 December 2020

Quantification of the vascular endothelial growth factor with a bioluminescence resonance energy transfer (BRET) based single molecule biosensor.

1 reference

12 December 2020

A far-red fluorescent protein evolved from a cyanobacterial phycobiliprotein

1 reference

12 December 2020

GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling

1 reference

12 December 2020

FRET binding antenna reports spatiotemporal dynamics of GDI-Cdc42 GTPase interactions

1 reference

12 December 2020

Bright monomeric near-infrared fluorescent proteins as tags and biosensors for multiscale imaging

1 reference

12 December 2020

The Piconewton Force Awakens: Quantifying Mechanics in Cells.

1 reference

12 December 2020

Dual Readout BRET/FRET Sensors for Measuring Intracellular Zinc

1 reference

12 December 2020

A FRET biosensor reveals spatiotemporal activation and functions of aurora kinase A in living cells

1 reference

12 December 2020

cAMP Signals in Drosophila Motor Neurons Are Confined to Single Synaptic Boutons.

1 reference

12 December 2020

Coupling optogenetic stimulation with NanoLuc-based luminescence (BRET) Ca sensing

1 reference

12 December 2020

Fluorescent indicators for simultaneous reporting of all four cell cycle phases

1 reference

12 December 2020

The Growing and Glowing Toolbox of Fluorescent and Photoactive Proteins

1 reference

12 December 2020

Mapping synaptic glutamate transporter dysfunction in vivo to regions surrounding Aβ plaques by iGluSnFR two-photon imaging

1 reference

12 December 2020

In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration

1 reference

12 December 2020

All-optical functional synaptic connectivity mapping in acute brain slices using the calcium integrator CaMPARI.

1 reference

12 December 2020

RasIns: Genetically Encoded Intrabodies of Activated Ras Proteins

1 reference

12 December 2020

Ratiometric and photoconvertible fluorescent protein-based voltage indicator prototypes.

1 reference

12 December 2020

mScarlet: a bright monomeric red fluorescent protein for cellular imaging

1 reference

12 December 2020

A FRET Biosensor for ROCK Based on a Consensus Substrate Sequence Identified by KISS Technology.

1 reference

12 December 2020

A comprehensive map of molecular drug targets.

1 reference

12 December 2020

Five colour variants of bright luminescent protein for real-time multicolour bioimaging

1 reference

12 December 2020

BTeam, a Novel BRET-based Biosensor for the Accurate Quantification of ATP Concentration within Living Cells

1 reference

12 December 2020

Dual observation of the ATP-evoked small GTPase activation and Ca2 transient in astrocytes using a dark red fluorescent protein.

1 reference

12 December 2020

β2-adrenergic receptor control of endosomal PTH receptor signaling via Gβγ.

1 reference

12 December 2020

Directed Evolution of Key Residues in Fluorescent Protein Inverses the Polarity of Voltage Sensitivity in the Genetically Encoded Indicator ArcLight

1 reference

12 December 2020

Multiplexing PKA and ERK1&2 kinases FRET biosensors in living cells using single excitation wavelength dual colour FLIM.

1 reference

12 December 2020

Axonal Endoplasmic Reticulum Ca2 Content Controls Release Probability in CNS Nerve Terminals

1 reference

12 December 2020

AKAP-mediated feedback control of cAMP gradients in developing hippocampal neurons

1 reference

12 December 2020

The GCaMP-R Family of Genetically Encoded Ratiometric Calcium Indicators.

1 reference

12 December 2020

Genetically encoded bioluminescent voltage indicator for multi-purpose use in wide range of bioimaging

1 reference

12 December 2020

Quantification of labile heme in live malaria parasites using a genetically encoded biosensor

1 reference

12 December 2020

Genetically encoded biosensors for visualizing live-cell biochemical activity at super-resolution

1 reference

12 December 2020

The mystery of membrane organization: composition, regulation and roles of lipid rafts

1 reference

12 December 2020

A Ratiometric Sensor for Imaging Insulin Secretion in Single β Cells

1 reference

12 December 2020

Temporally precise labeling and control of neuromodulatory circuits in the mammalian brain

1 reference

12 December 2020

Near-Infrared Fluorescent Proteins, Biosensors, and Optogenetic Tools Engineered from Phytochromes

1 reference

12 December 2020

Experimental and mathematical analysis of cAMP nanodomains

1 reference

12 December 2020

Liberated PKA Catalytic Subunits Associate with the Membrane via Myristoylation to Preferentially Phosphorylate Membrane Substrates

1 reference

12 December 2020

Identification of a multienzyme complex for glucose metabolism in living cells

1 reference

12 December 2020

FRET biosensor uncovers cAMP nano-domains at β-adrenergic targets that dictate precise tuning of cardiac contractility

1 reference

12 December 2020

PDE2A2 regulates mitochondria morphology and apoptotic cell death via local modulation of cAMP/PKA signalling

1 reference

12 December 2020

FRET-based Visualization of PDGF Receptor Activation at Membrane Microdomains

1 reference

12 December 2020

Protein O-GlcNAcylation: emerging mechanisms and functions

1 reference

12 December 2020

A novel FbFP-based biosensor toolbox for sensitive in vivo determination of intracellular pH.

1 reference

12 December 2020

Flow-induced endothelial cell alignment requires the RhoGEF Trio as a scaffold protein to polarize active Rac1 distribution.

1 reference

12 December 2020

Flashbody: A Next Generation Fluobody with Fluorescence Intensity Enhanced by Antigen Binding

1 reference

12 December 2020

Genetically encoded fluorescent sensors reveal dynamic regulation of NADPH metabolism

1 reference

12 December 2020

Genetic evidence that β-arrestins are dispensable for the initiation of β2-adrenergic receptor signaling to ERK.

1 reference

12 December 2020

Local protein kinase A action proceeds through intact holoenzymes.

1 reference

12 December 2020

A calcium- and light-gated switch to induce gene expression in activated neurons

1 reference

12 December 2020

A light- and calcium-gated transcription factor for imaging and manipulating activated neurons

1 reference

12 December 2020

Monitoring thioredoxin redox with a genetically encoded red fluorescent biosensor.

1 reference

12 December 2020

Photoacoustic imaging using genetically encoded reporters: a review

1 reference

12 December 2020

Generation of a cGMP Indicator with an Expanded Dynamic Range by Optimization of Amino Acid Linkers between a Fluorescent Protein and PDE5α.

1 reference

12 December 2020

Nanobody Technology: A Versatile Toolkit for Microscopic Imaging, Protein-Protein Interaction Analysis, and Protein Function Exploration.

1 reference

12 December 2020

ShadowY: a dark yellow fluorescent protein for FLIM-based FRET measurement.

1 reference

12 December 2020

Red fluorescent protein-based cAMP indicator applicable to optogenetics and in vivo imaging

1 reference

12 December 2020

ER/K linked GPCR-G protein fusions systematically modulate second messenger response in cells

1 reference

12 December 2020

Systematic gene tagging using CRISPR/Cas9 in human stem cells to illuminate cell organization

1 reference

12 December 2020

Mapping the 'Two-component system' network in rice

1 reference

12 December 2020

A Bimolecular Fluorescence Complementation Tool for Identification of Protein-Protein Interactions in Candida albicans

1 reference

12 December 2020

Insertion of the voltage-sensitive domain into circularly permuted red fluorescent protein as a design for genetically encoded voltage sensor.

1 reference

12 December 2020

Single-Domain Antibodies As Versatile Affinity Reagents for Analytical and Diagnostic Applications

1 reference

12 December 2020

Internalized TSH receptors en route to the TGN induce local Gs-protein signaling and gene transcription

1 reference

12 December 2020

Ratiometric Matryoshka biosensors from a nested cassette of green- and orange-emitting fluorescent proteins

1 reference

12 December 2020

Mechanisms for restraining cAMP-dependent protein kinase revealed by subunit quantitation and cross-linking approaches

1 reference

12 December 2020

SRpHi ratiometric pH biosensors for super-resolution microscopy

1 reference

12 December 2020

Split GFP technologies to structurally characterize and quantify functional biomolecular interactions of FTD-related proteins

1 reference

12 December 2020

hERG1a and hERG1b potassium channel subunits directly interact and preferentially form heteromeric channels.

1 reference

12 December 2020

Genetically Encoded Tools for Optical Dissection of the Mammalian Cell Cycle.

1 reference

12 December 2020

FRET Analysis of the Promiscuous yet Specific Interactions of the HIV-1 Vpu Transmembrane Domain

1 reference

12 December 2020

FRET analysis of HIV-1 Gag and GagPol interactions

1 reference

12 December 2020

Comparative cell cycle transcriptomics reveals synchronization of developmental transcription factor networks in cancer cells

1 reference

12 December 2020

The mito::mKate2 mouse: A far-red fluorescent reporter mouse line for tracking mitochondrial dynamics in vivo

1 reference

12 December 2020

A genetically encoded Ca2 indicator based on circularly permutated sea anemone red fluorescent protein eqFP578.

1 reference

12 December 2020

Single-cell bioluminescence imaging of deep tissue in freely moving animals

1 reference

12 December 2020

A robotic multidimensional directed evolution approach applied to fluorescent voltage reporters

1 reference

12 December 2020

A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis.

1 reference

12 December 2020