α-Toxin Induces Platelet Aggregation and Liver Injury during Staphylococcus aureus Sepsis (Q90392500)

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13 April 2020

title

α-Toxin Induces Platelet Aggregation and Liver Injury during Staphylococcus aureus Sepsis (English)

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13 April 2020

main subject

Staphylococcus aureus

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5

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Juliane Bubeck Wardenburg

13 April 2020

9

object named as

Juliane Bubeck Wardenburg

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13 April 2020

author name string

Bas G J Surewaard

1

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13 April 2020

Ajitha Thanabalasuriar

2

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13 April 2020

Zhutian Zeng

3

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13 April 2020

Christine Tkaczyk

4

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Bart W Bardoel

6

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Selina K Jorch

7

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Carsten Deppermann

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Rachelle P Davis

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Craig N Jenne

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Kendall C Stover

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Bret R Sellman

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Paul Kubes

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publication date

19 July 2018

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volume

24

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issue

2

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page(s)

271-284.e3

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Disseminated intravascular coagulation associated with Staphylococcus aureus septicemia is mediated by peptidoglycan-induced platelet aggregation

13 April 2020

cites work

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12 December 2020

Staphylococcal α toxin promotes blood coagulation via attack on human platelets

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12 December 2020

Heat Stability and Species Range of Purified Staphylococcal α-Toxin

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12 December 2020

Staphylococcus aureus infections

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12 December 2020

Disseminated intravascular coagulation

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12 December 2020

Role of Fc receptor gamma-chain in platelet glycoprotein Ib-mediated signaling

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12 December 2020

ACTION OF STAPHYLOCOCCAL TOXIN ON HUMAN PLATELETS

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12 December 2020

CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens

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12 December 2020

Identification of novel cytolytic peptides as key virulence determinants for community-associated MRSA

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Host-pathogen interactions in sepsis

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12 December 2020

Poring over pores: alpha-hemolysin and Panton-Valentine leukocidin in Staphylococcus aureus pneumonia

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12 December 2020

Vaccine protection against Staphylococcus aureus pneumonia

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Platelets, petechiae, and preservation of the vascular wall

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12 December 2020

Harmful molecular mechanisms in sepsis

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12 December 2020

Platelets kill intraerythrocytic malarial parasites and mediate survival to infection

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12 December 2020

Anti-alpha-hemolysin monoclonal antibodies mediate protection against Staphylococcus aureus pneumonia

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12 December 2020

Waves of resistance: Staphylococcus aureus in the antibiotic era.

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12 December 2020

Platelets display potent antimicrobial activity and release human beta-defensin 2

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12 December 2020

A Staphylococcus aureus pore-forming toxin subverts the activity of ADAM10 to cause lethal infection in mice

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12 December 2020

The use of spinning-disk confocal microscopy for the intravital analysis of platelet dynamics in response to systemic and local inflammation

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12 December 2020

How Staphylococcus aureus biofilms develop their characteristic structure.

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12 December 2020

Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo.

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12 December 2020

CCR5 is a receptor for Staphylococcus aureus leukotoxin ED.

1 reference

12 December 2020

Multiphoton imaging reveals a new leukocyte recruitment paradigm in the glomerulus

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12 December 2020

Hierarchical organization in the hemostatic response and its relationship to the platelet-signaling network

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12 December 2020

Mechanism of action and in vivo efficacy of a human-derived antibody against Staphylococcus aureus α-hemolysin

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12 December 2020

Staphylococcal alpha-phenol soluble modulins contribute to neutrophil lysis after phagocytosis.

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12 December 2020

Staphylococcus aureus α-hemolysin promotes platelet-neutrophil aggregate formation

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12 December 2020

Nucleation of platelets with blood-borne pathogens on Kupffer cells precedes other innate immunity and contributes to bacterial clearance

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12 December 2020

Neutrophils versus Staphylococcus aureus: a biological tug of war.

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12 December 2020

Staphylococcus aureus α-toxin: nearly a century of intrigue

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12 December 2020

Assessment of an anti-alpha-toxin monoclonal antibody for prevention and treatment of Staphylococcus aureus-induced pneumonia

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12 December 2020

Igniting the fire: Staphylococcus aureus virulence factors in the pathogenesis of sepsis

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12 December 2020

Targeting Staphylococcus aureus α-toxin as a novel approach to reduce severity of recurrent skin and soft-tissue infections

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12 December 2020

Superantigens subvert the neutrophil response to promote abscess formation and enhance Staphylococcus aureus survival in vivo

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12 December 2020

Differential expression and roles of Staphylococcus aureus virulence determinants during colonization and disease

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12 December 2020

Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature.

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12 December 2020

An ADAM10 promoter polymorphism is a functional variant in severe sepsis patients and confers susceptibility to the development of sepsis.

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12 December 2020

MEDI4893* Promotes Survival and Extends the Antibiotic Treatment Window in a Staphylococcus aureus Immunocompromised Pneumonia Model

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12 December 2020

Synergistic Action of Staphylococcus aureus α-Toxin on Platelets and Myeloid Lineage Cells Contributes to Lethal Sepsis

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12 December 2020

Pathogenesis of Staphylococcus aureus Bloodstream Infections

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12 December 2020

Staphylococcus aureus α toxin potentiates opportunistic bacterial lung infections

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12 December 2020

Genome-wide CRISPR screen reveals novel host factors required for Staphylococcus aureus α-hemolysin-mediated toxicity.

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12 December 2020

Identification and treatment of the Staphylococcus aureus reservoir in vivo

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12 December 2020

CRIg Functions as a Macrophage Pattern Recognition Receptor to Directly Bind and Capture Blood-Borne Gram-Positive Bacteria.

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12 December 2020

Targeting Alpha Toxin and ClfA with a Multimechanistic Monoclonal-Antibody-Based Approach for Prophylaxis of Serious Staphylococcus aureus Disease

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12 December 2020

Critical Role of Alpha-Toxin and Protective Effects of Its Neutralization by a Human Antibody in Acute Bacterial Skin and Skin Structure Infections

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12 December 2020

Staphylococcus aureus α-Toxin Response Distinguishes Respiratory Virus-Methicillin-Resistant S. aureus Coinfection in Children

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12 December 2020

Leukocidins: staphylococcal bi-component pore-forming toxins find their receptors.

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12 December 2020

The immunopathology of sepsis and potential therapeutic targets

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12 December 2020

Bispecific antibody targets multiple Pseudomonas aeruginosa evasion mechanisms in the lung vasculature

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12 December 2020

Measurement of bacterial capture and phagosome maturation of Kupffer cells by intravital microscopy

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12 December 2020

Multimechanistic Monoclonal Antibodies (MAbs) Targeting Staphylococcus aureus Alpha-Toxin and Clumping Factor A: Activity and Efficacy Comparisons of a MAb Combination and an Engineered Bispecific Antibody Approach

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12 December 2020

Neutrophil evasion strategies by Streptococcus pneumoniae and Staphylococcus aureus

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12 December 2020

10.1016/J.CHOM.2018.06.017

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30033122 AND SRC:MED&resulttype=core&format=json

13 April 2020

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13 April 2020

PubMed publication ID

30033122

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