The Role of the Lymphocyte Functional Crosstalk and Regulation in the Context of Checkpoint Inhibitor Treatment-Review (Q90290702)

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12 April 2020

review article

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8 February 2021

The Role of the Lymphocyte Functional Crosstalk and Regulation in the Context of Checkpoint Inhibitor Treatment-Review (English)

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12 April 2020

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8 February 2021

1

Barbara Seliger

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publication date

6 September 2019

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8 February 2021

Frontiers in Immunology

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8 February 2021

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Creative Commons Attribution 4.0 International

12 April 2020

copyright license

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Clinical applications of tissue expansion in head and neck surgery

8 February 2021

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Acquired resistance to fractionated radiotherapy can be overcome by concurrent PD-L1 blockade

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The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints

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High Expression of Human Leukocyte Antigen-G is Associated with a Poor Prognosis in Patients with PDAC.

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Intratumoral tertiary lymphoid organ is a favourable prognosticator in patients with pancreatic cancer

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Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity

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Induction of PD-L1 Expression by the EML4-ALK Oncoprotein and Downstream Signaling Pathways in Non-Small Cell Lung Cancer

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Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities

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HLA-G: An Immune Checkpoint Molecule

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12 December 2020

Adaptive Immune Resistance: How Cancer Protects from Immune Attack

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12 December 2020

Genomic correlates of response to CTLA-4 blockade in metastatic melanoma

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12 December 2020

Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

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12 December 2020

Immune suppressive mechanisms in the tumor microenvironment

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12 December 2020

PD-L1 Is Upregulated by Simultaneous Amplification of the PD-L1 and JAK2 Genes in Non-Small Cell Lung Cancer

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12 December 2020

Acquired resistance to immunotherapy and future challenges

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Epithelial-Mesenchymal Transition Is Associated with a Distinct Tumor Microenvironment Including Elevation of Inflammatory Signals and Multiple Immune Checkpoints in Lung Adenocarcinoma

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12 December 2020

Coinhibitory Pathways in Immunotherapy for Cancer

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HLA-G and classical HLA class I expression in primary colorectal cancer and associated liver metastases.

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12 December 2020

The future of cancer treatment: immunomodulation, CARs and combination immunotherapy

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Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma

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Tremelimumab: research and clinical development

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Clinical significance of PD-L1 and PD-L2 copy number gains in non-small-cell lung cancer

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Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation.

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Reprogramming Tumor-Associated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis

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Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma

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Abscopal Effects of Radiotherapy Are Enhanced by Combined Immunostimulatory mAbs and Are Dependent on CD8 T Cells and Crosspriming.

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Tumor interferon signaling regulates a multigenic resistance program to immune checkpoint blockade

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PD-L1, PD-L2 and PD-1 expression in metastatic melanoma: Correlation with tumor-infiltrating immune cells and clinical outcome

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Temporally Distinct PD-L1 Expression by Tumor and Host Cells Contributes to Immune Escape

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Radiotherapy and Immune Checkpoint Blockade for Melanoma: A Promising Combinatorial Strategy in Need of Further Investigation

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Dendritic cells in cancer: the role revisited

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PD-1 and PD-L1 antibodies in cancer: current status and future directions

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Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance.

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Immunoregulatory functions of VISTA.

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Tim-3 and its role in regulating anti-tumor immunity

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The ectonucleotidases CD39 and CD73: Novel checkpoint inhibitor targets

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Potential targeting of B7-H4 for the treatment of cancer.

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Baseline gut microbiota predicts clinical response and colitis in metastatic melanoma patients treated with ipilimumab

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T-cell invigoration to tumour burden ratio associated with anti-PD-1 response.

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T cell cross-reactivity may explain the large variation in how patients respond to checkpoint inhibitors.

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HLA class I loss and PD-L1 expression in lung cancer: impact on T-cell infiltration and immune escape.

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Genetic mechanisms of immune evasion in colorectal cancer

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MET-Oncogenic and JAK2-Inactivating Alterations Are Independent Factors That Affect Regulation of PD-L1 Expression in Lung Cancer

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Genomic ERBB2/ERBB3 mutations promote PD-L1-mediated immune escape in gallbladder cancer: a whole-exome sequencing analysis

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γδ T Cells: Crosstalk Between Microbiota, Chronic Inflammation, and Colorectal Cancer

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A dormant TIL phenotype defines non-small cell lung carcinomas sensitive to immune checkpoint blockers

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Radiation-Induced Transformation of Immunoregulatory Networks in the Tumor Stroma

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Avelumab in non-small-cell lung cancer

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The promising immune checkpoint LAG-3: from tumor microenvironment to cancer immunotherapy.

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Analysis of the Tumor Reactivity of Tumor-Infiltrating Lymphocytes in a Metastatic Melanoma Lesion that Lost Major Histocompatibility Complex Class I Expression after Anti-PD-1 Therapy

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Blocking Triggering Receptor Expressed on Myeloid Cells-1-Positive Tumor-Associated Macrophages Induced by Hypoxia Reverses Immunosuppression and Anti-Programmed Cell Death Ligand 1 Resistance in Liver Cancer

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Cognate Interaction With CD4 T Cells Instructs Tumor-Associated Macrophages to Acquire M1-Like Phenotype

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Identifiers

DOI

10.3389/FIMMU.2019.02043

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31555274 AND SRC:MED&resulttype=core&format=json

12 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31555274 AND SRC:MED&resulttype=core&format=json

12 April 2020

PubMed publication ID

31555274

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