Extensive Changes in Transcriptomic "Fingerprints" and Immunological Cells in the Large Organs of Patients Dying of Acute Septic Shock and Multiple Organ Failure Caused by Neisseria meningitidis (Q90179453)

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scientific article published on 19 February 2020

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English	Extensive Changes in Transcriptomic "Fingerprints" and Immunological Cells in the Large Organs of Patients Dying of Acute Septic Shock and Multiple Organ Failure Caused by Neisseria meningitidis	scientific article published on 19 February 2020

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12 April 2020

Extensive Changes in Transcriptomic "Fingerprints" and Immunological Cells in the Large Organs of Patients Dying of Acute Septic Shock and Multiple Organ Failure Caused by Neisseria meningitidis (English)

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12 April 2020

Neisseria meningitidis

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Berit Sletbakk Brusletto

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12 April 2020

Else Marit Løberg

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12 April 2020

Bernt Christian Hellerud

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Ingeborg Løstegaard Goverud

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Jens Petter Berg

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Ole Kristoffer Olstad

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12 April 2020

Unni Gopinathan

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Petter Brandtzaeg

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Reidun Øvstebø

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12 April 2020

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19 February 2020

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12 April 2020

Frontiers in Cellular and Infection Microbiology

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12 April 2020

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12 April 2020

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12 April 2020

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Creative Commons Attribution 4.0 International

19 February 2020

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April 2022 Public Data File from Crossref

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0 references

Compartmentalization of lipopolysaccharide production correlates with clinical presentation in meningococcal disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of myocarditis and acute renal failure complicating meningococcal septicaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasminogen activator inhibitor 1 and 2, alpha-2-antiplasmin, plasminogen, and endotoxin levels in systemic meningococcal disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complement activation and endotoxin levels in systemic meningococcal disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma endotoxin as a predictor of multiple organ failure and death in systemic meningococcal disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The quantitative association of plasma endotoxin, antithrombin, protein C, extrinsic pathway inhibitor and fibrinopeptide A in systemic meningococcal disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Local production of tumor necrosis factor alpha, interleukin 1, and interleukin 6 in meningococcal meningitis. Relation to the inflammatory response

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1, and fatal outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hemodynamic patterns of meningococcal shock in children

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Case fatality of meningococcal disease in western Norway

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myocardial dysfunction in children with acute meningococcemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An epidemiological, clinical and microbiological follow-up study of incident meningococcal disease cases in Norway, winter 1981-1982. Material and epidemiology in the MenOPP project

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased tissue thromboplastin activity in monocytes of patients with meningococcal infection: related to an unfavourable prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between proinflammatory cytokines and antiinflammatory mediators and the severity of disease in meningococcal infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatal meningococcal disease in childhood: an autopsy study of 86 cases

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High levels of interleukin 10 in serum are associated with fatality in meningococcal disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The excessive complement activation in fulminant meningococcal septicemia is predominantly caused by alternative pathway activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relationship between plasminogen activator inhibitor-1 and proinflammatory and counterinflammatory mediators in children with meningococcal septic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Net inflammatory capacity of human septic shock plasma evaluated by a monocyte-based target cell assay: identification of interleukin-10 as a major functional deactivator of human monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related differences in outcome and severity of DIC in children with septic shock and purpura.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A physiologic function for alkaline phosphatase: endotoxin detoxification.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pattern of interleukin-1beta (IL-1beta) and its modulating agents IL-1 receptor antagonist and IL-1 soluble receptor type II in acute meningococcal infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional and clinical aspects of the myelomonocyte protein calprotectin

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathophysiology of meningococcal sepsis in children

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelial cell adhesion molecules in meningococcal disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HMG-1 as a late mediator of endotoxin lethality in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Optimization of the Isolation and Amplification of RNA From Formalin-fixed, Paraffin-embedded Tissue: The Armed Forces Institute of Pathology Experience and Literature Review

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Meningococcal disease in a large urban population (Barcelona, 1987-1992): predictors of dismal prognosis. Barcelona Meningococcal Disease Surveillance Group.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Update on meningococcal disease with emphasis on pathogenesis and clinical management

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

14-3-3 proteins block apoptosis and differentially regulate MAPK cascades

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The acute phase response is associated with retinoid X receptor repression in rodent liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Life-threatening heart failure in meningococcal septic shock in children: non-invasive measurement of cardiac parameters is of important prognostic value

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequency of myocarditis in cases of fatal meningococcal infection in children: observations on 31 cases studied at autopsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A myocardial cytotoxic process is involved in the cardiac dysfunction of meningococcal septic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parents' and GPs' key role in diagnosis of meningococcal septicaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Meningococcal disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic response to sepsis: interaction between coagulation and inflammatory processes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dysfunction of Endothelial Protein C Activation in Severe Meningococcal Sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neisseria meningitidis lipopolysaccharides in human pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Meningococcal bacterial DNA load at presentation correlates with disease severity

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The plasma kallikrein-kinin system counterbalances the renin-angiotensin system

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ICAM-1 and VCAM-1 mediate endotoxemic myocardial dysfunction independent of neutrophil accumulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ST2 protein induced by inflammatory stimuli can modulate acute lung inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress and gene expression in sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new strategy to amplify degraded RNA from small tissue samples for microarray studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathophysiology of meningococcal meningitis and septicaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impairment of glucose metabolism in hearts from rats treated with endotoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of interleukin 6 in myocardial dysfunction of meningococcal septic shock.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of robotized DNA isolation and real-time PCR to quantify and identify close correlation between levels of Neisseria meningitidis DNA and lipopolysaccharides in plasma and cerebrospinal fluid from patients with systemic meningococcal disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PI3K-Akt pathway suppresses coagulation and inflammation in endotoxemic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear receptors in macrophage biology: at the crossroads of lipid metabolism and inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathogenesis and diagnosis of human meningococcal disease using immunohistochemical and PCR assays.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemokine patterns in meningococcal disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Both percentage of gammadelta T lymphocytes and CD3 expression are reduced during septic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The RIN: an RNA integrity number for assigning integrity values to RNA measurements

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Liver X receptors as integrators of metabolic and inflammatory signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased case-fatality rate associated with outbreaks of Neisseria meningitidis infection, compared with sporadic meningococcal disease, in the United States, 1994-2002.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebral microcirculation shear stress levels determine Neisseria meningitidis attachment sites along the blood-brain barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasminogen activator inhibitor 1 promotes a poor prognosis in sepsis-induced disseminated intravascular coagulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A host lipase detoxifies bacterial lipopolysaccharides in the liver and spleen

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temporal dynamics of gene expression in the lung in a baboon model of E. coli sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial dysfunction, bioenergetic impairment, and metabolic down-regulation in sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidemic meningitis, meningococcaemia, and Neisseria meningitidis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sepsis-induced coagulation in the baboon lung is associated with decreased tissue factor pathway inhibitor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptor 4 is a sensor for autophagy associated with innate immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determinants of RNA quality from FFPE samples

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Critical role of p38 mitogen-activated protein kinase signaling in septic lung injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RNA extraction from ten year old formalin-fixed paraffin-embedded breast cancer samples: a comparison of column purification and magnetic bead-based technologies

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of processing delay, formalin fixation, and immunohistochemistry on RNA Recovery From Formalin-fixed Paraffin-embedded Tissue Sections.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complementary roles for biomarkers of biomechanical strain ST2 and N-terminal prohormone B-type natriuretic peptide in patients with ST-elevation myocardial infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pre-admission clinical course of meningococcal disease and opportunities for the earlier start of appropriate intervention: a prospective epidemiological study on 752 patients in the Netherlands, 2003-2005

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LPS decreases fatty acid oxidation and nuclear hormone receptors in the kidney

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RNA expression analysis from formalin fixed paraffin embedded tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Factors in tissue handling and processing that impact RNA obtained from formalin-fixed, paraffin-embedded tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fulminating meningococcic infections and the so-called Waterhouse-Friderichsen syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functions and pathologies of BiP and its interaction partners

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methods comparison for high-resolution transcriptional analysis of archival material on Affymetrix Plus 2.0 and Exon 1.0 microarrays

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical detection of CCR2 and CX3CR1 in sepsis-induced lung injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MicroRNA fingerprints identify miR-150 as a plasma prognostic marker in patients with sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiac overexpression of metallothionein rescues cardiac contractile dysfunction and endoplasmic reticulum stress but not autophagy in sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms of the LPS-induced non-apoptotic ER stress-CHOP pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissecting the effects of lipopolysaccharides from nonlipopolysaccharide molecules in experimental porcine meningococcal sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of Escherichia coli sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial dysfunction during sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative expression profiling in formalin-fixed paraffin-embedded samples by affymetrix microarrays

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 receptor-associated kinase 3 gene associates with susceptibility to acute lung injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional profiling and genotyping of degraded nucleic acids from autopsy tissue samples after prolonged formalin fixation times

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression profiles from formalin fixed paraffin embedded breast cancer tissue are largely comparable to fresh frozen matched tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interrelationship between cardiac hypertrophy, heart failure, and chronic kidney disease: endoplasmic reticulum stress as a mediator of pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myocardial depressant effects of interleukin 6 in meningococcal sepsis are regulated by p38 mitogen-activated protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetics of Interleukin 1 Receptor-Like 1 in Immune and Inflammatory Diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of c-Jun-N-terminal kinase increases cardiac peroxisome proliferator-activated receptor alpha expression and fatty acid oxidation and prevents lipopolysaccharide-induced heart dysfunction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Classification and pathogenesis of meningococcal infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Meningococcal disease in children in Merseyside, England: a 31 year descriptive study

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neisseria meningitidis induces platelet inhibition and increases vascular endothelial permeability via nitric oxide regulated pathways.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced Peroxisome Proliferator-Activated Receptor α Expression Is Associated With Decreased Survival and Increased Tissue Bacterial Load in Sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression analysis on archival material: comparison of 5 commercially available RNA isolation kits for FFPE material

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LPS from Neisseria meningitidis is crucial for inducing monocyte- and microparticle-associated tissue factor activity but not for tissue factor expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Postmortem cardiac tissue maintains gene expression profile even after late harvesting.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleic acids from long-term preserved FFPE tissues are suitable for downstream analyses.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proximal tubule haptoglobin gene activation is an integral component of the acute kidney injury "stress response".

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of β1 integrin in tissue homing of neutrophils during sepsis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Eukaryotic initiation factor 2 (eIF2) signaling regulates proinflammatory cytokine expression and bacterial invasion

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Liver X receptor and peroxisome proliferator-activated receptor as integrators of lipid homeostasis and immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global effect of interleukin-10 on the transcriptional profile induced by Neisseria meningitidis in human monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

14-3-3ε plays a role in cardiac ventricular compaction by regulating the cardiomyocyte cell cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical review: The liver in sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasminogen activator inhibitor-1 in kidney pathology (Review).

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of cardiac and renal dysfunction in patients dying of sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adhesion of Neisseria meningitidis to dermal vessels leads to local vascular damage and purpura in a humanized mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular basis for manganese sequestration by calprotectin and roles in the innate immune response to invading bacterial pathogens

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipopolysaccharide clearance, bacterial clearance, and systemic inflammatory responses are regulated by cell type-specific functions of TLR4 during sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor-γ activation prevents sepsis-related cardiac dysfunction and mortality in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An optimized workflow for improved gene expression profiling for formalin-fixed, paraffin-embedded tumor samples

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microparticle-associated tissue factor activity is reduced by inhibition of the complement protein 5 in Neisseria meningitidis-exposed whole blood

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute kidney injury is surprisingly common and a powerful predictor of mortality in surgical sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microparticle-associated tissue factor activity correlates with plasma levels of bacterial lipopolysaccharides in meningococcal septic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

S100A8 and S100A9: DAMPs at the crossroads between innate immunity, traditional risk factors, and cardiovascular disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression profiling in sepsis: timing, tissue, and translational considerations

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-mobility group box 1 (HMGB1) impaired cardiac excitation-contraction coupling by enhancing the sarcoplasmic reticulum (SR) Ca(2 ) leak through TLR4-ROS signaling in cardiomyocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of anti-inflammatory properties of ferritin light chain on lipopolysaccharide-induced inflammatory response in murine macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue damage control in disease tolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparing Platforms for Messenger RNA Expression Profiling of Archival Formalin-Fixed, Paraffin-Embedded Tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of Iron Metabolism by Hepcidin under Conditions of Inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross talk of the first-line defense TLRs with PI3K/Akt pathway, in preconditioning therapeutic approach

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disease Burden of Invasive Meningococcal Disease in the Netherlands Between June 1999 and June 2011: A Subjective Role for Serogroup and Clonal Complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ENDOPLASMIC RETICULUM STRESS IN SEPSIS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early and dynamic changes in gene expression in septic shock patients: a genome-wide approach

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mining the Archives: A Cross-Platform Analysis of Gene Expression Profiles in Archival Formalin-Fixed Paraffin-Embedded Tissues.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Massive Organ Inflammation in Experimental and in Clinical Meningococcal Septic Shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Novel Approach to High-Quality Postmortem Tissue Procurement: The GTEx Project

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endoplasmic reticulum stress and its effects on renal tubular cells apoptosis in ischemic acute kidney injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophagy in sepsis: Degradation into exhaustion?

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

miR-182 Regulates Metabolic Homeostasis by Modulating Glucose Utilization in Muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HMGB1, IL-1α, IL-33 and S100 proteins: dual-function alarmins

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular regulation of TNF activity in health and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of frozen tissue-derived prognostic gene expression signatures in FFPE colorectal cancer samples

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemokine CXCL1 mediated neutrophil recruitment: Role of glycosaminoglycan interactions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The involvement of regulatory non-coding RNAs in sepsis: a systematic review.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TNFα-stimulated gene-6 (TSG6) activates macrophage phenotype transition to prevent inflammatory lung injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sepsis and septic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Starving for survival-how catabolic metabolism fuels immune function

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of iron in the pathogenesis of respiratory disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleic acid extraction from formalin-fixed paraffin-embedded cancer cell line samples: a trade off between quantity and quality?

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Traceability and distribution of Neisseria meningitidis DNA in archived post mortem tissue samples from patients with systemic meningococcal disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-coding RNA: a potential biomarker and therapeutic target for sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Review of Interleukin-1 in Heart Disease: Where Do We Stand Today?

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of miR-182-5p protects cardiomyocytes from hypoxia-induced apoptosis by targeting CIAPIN1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Multifaceted Effects of Alpha1-Antitrypsin on Neutrophil Functions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting β1-integrin inhibits vascular leakage in endotoxemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

S100A8/A9 in Inflammation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasminogen Activator Inhibitor 1 for Predicting Sepsis Severity and Mortality Outcomes: A Systematic Review and Meta-Analysis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reprogramming of basic metabolic pathways in microbial sepsis: therapeutic targets at last?

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Septic Heart: Current Understanding of Molecular Mechanisms and Clinical Implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bacterial sepsis triggers an antiviral response that causes translation shutdown

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

, , and Polymorphisms Predict Septic-Shock-Related Death in Patients Who Underwent Major Surgery

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid evolution and conserved function of the piRNA pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of Long Noncoding RNA and mRNA Profiles in Sepsis-Induced Myocardial Depression

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific PIWI-interacting small noncoding RNA expression patterns in pulmonary tuberculosis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/32154187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3389/FCIMB.2020.00042

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32154187 AND SRC:MED&resulttype=core&format=json

12 April 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32154187 AND SRC:MED&resulttype=core&format=json

12 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32154187 AND SRC:MED&resulttype=core&format=json

12 April 2020

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