Modelling the endocrine pancreas in health and disease (Q90036861)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30504925 AND SRC:MED&resulttype=core&format=json

10 April 2020

title

Modelling the endocrine pancreas in health and disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30504925 AND SRC:MED&resulttype=core&format=json

10 April 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30504925 AND SRC:MED&resulttype=core&format=json

10 April 2020

Anika Böttcher

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30504925 AND SRC:MED&resulttype=core&format=json

10 April 2020

author name string

Heiko Lickert

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30504925 AND SRC:MED&resulttype=core&format=json

10 April 2020

publication date

1 March 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30504925 AND SRC:MED&resulttype=core&format=json

Nature Reviews Endocrinology

10 April 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30504925 AND SRC:MED&resulttype=core&format=json

10 April 2020

volume

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30504925 AND SRC:MED&resulttype=core&format=json

10 April 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30504925 AND SRC:MED&resulttype=core&format=json

10 April 2020

page(s)

155-171

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30504925 AND SRC:MED&resulttype=core&format=json

10 April 2020

cites work

Type 1 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Residual insulin production and pancreatic ß-cell turnover after 50 years of diabetes: Joslin Medalist Study.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Pancreatic islet regeneration through PDX-1/Notch-1/Ngn3 signaling after gastric bypass surgery in db/db mice

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Pancreatic hyperplasia after gastric bypass surgery in a GK rat model of non-obese type 2 diabetes

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Remission of Human Type 2 Diabetes Requires Decrease in Liver and Pancreas Fat Content but Is Dependent upon Capacity for β Cell Recovery

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

International trial of the Edmonton protocol for islet transplantation.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Vertebrate endoderm development and organ formation

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Molecular basis of vertebrate endoderm development

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

A glimpse into the molecular entrails of endoderm formation.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Development of the human pancreas from foregut to endocrine commitment.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Human pancreas development

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Pancreas development in humans

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Laser Capture and Deep Sequencing Reveals the Transcriptomic Programmes Regulating the Onset of Pancreas and Liver Differentiation in Human Embryos.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Animal models have little to teach us about type 1 diabetes: 2. In opposition to this proposal

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Animal models have little to teach us about type 1 diabetes: 1. In support of this proposal

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Generation of functional human pancreatic β cells in vitro

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Impact of islet architecture on β-cell heterogeneity, plasticity and function

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Cellular and molecular mechanisms coordinating pancreas development

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Pancreas organogenesis: From bud to plexus to gland

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Pancreas organogenesis: from lineage determination to morphogenesis

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

The molecular and morphogenetic basis of pancreas organogenesis

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Pancreatic regulation of glucose homeostasis

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Gastrin: a distinct fate of neurogenin3 positive progenitor cells in the embryonic pancreas

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Ghrelin expression in the mouse pancreas defines a unique multipotent progenitor population

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Developmental biology of the pancreas: a comprehensive review

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Cdc42-mediated tubulogenesis controls cell specification

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Epithelial dynamics of pancreatic branching morphogenesis

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Feedback control of growth, differentiation, and morphogenesis of pancreatic endocrine progenitors in an epithelial plexus niche.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Neurogenin3 initiates stepwise delamination of differentiating endocrine cells during pancreas development.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Vascular instruction of pancreas development

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Neural regulation of pancreatic islet cell mass and function

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Early pattern of differentiation in the human pancreas

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Identification of known and novel pancreas genes expressed downstream of Nkx2.2 during development

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

The window period of NEUROGENIN3 during human gestation

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Endocrine cell clustering during human pancreas development

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Understanding human fetal pancreas development using subpopulation sorting, RNA sequencing and single-cell profiling

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Reconstructing human pancreatic differentiation by mapping specific cell populations during development.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

The genetics of type 2 diabetes: what have we learned from GWAS?

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Type 1 diabetes genome-wide association studies: not to be lost in translation

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

A genome-wide association study identifies novel risk loci for type 2 diabetes

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Monogenic diabetes in adults: what are the new developments?

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Beta-cell replication is the primary mechanism subserving the postnatal expansion of beta-cell mass in humans

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Early Developmental Perturbations in a Human Stem Cell Model of MODY5/HNF1B Pancreatic Hypoplasia

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Foxa2 and Pdx1 cooperatively regulate postnatal maturation of pancreatic β-cells

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

All mixed up: defining roles for β-cell subtypes in mature islets

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

β-Cells are not uniform after all-Novel insights into molecular heterogeneity of insulin-secreting cells

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

The role of beta cell heterogeneity in islet function and insulin release.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Development and dynamics of cell polarity at a glance

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Identification of proliferative and mature β-cells in the islets of Langerhans

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Planar cell polarity controls pancreatic beta cell differentiation and glucose homeostasis.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Human islets contain four distinct subtypes of β cells

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Single-Cell Mass Cytometry Analysis of the Human Endocrine Pancreas

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

The majority of patients with long-duration type 1 diabetes are insulin microsecretors and have functioning beta cells

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Inhibition of TGF-β Signaling Promotes Human Pancreatic β-Cell Replication.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

SerpinB1 Promotes Pancreatic β Cell Proliferation

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Replication confers β cell immaturity

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

β Cells that Resist Immunological Attack Develop during Progression of Autoimmune Diabetes in NOD Mice

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Persistence of Pancreatic Insulin mRNA Expression and Proinsulin Protein in Type 1 Diabetes Pancreata

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Pancreatic β cell dedifferentiation in diabetes and redifferentiation following insulin therapy

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

The Physiology and Molecular Underpinnings of the Effects of Bariatric Surgery on Obesity and Diabetes

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

A multipotent progenitor domain guides pancreatic organogenesis.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Precommitment low-level Neurog3 expression defines a long-lived mitotic endocrine-biased progenitor pool that drives production of endocrine-committed cells

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Notch signalling controls pancreatic cell differentiation

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Mesenchymal Hox6 function is required for mouse pancreatic endocrine cell differentiation

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

EGFR signalling controls cellular fate and pancreatic organogenesis by regulating apicobasal polarity.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Snail2, a mediator of epithelial-mesenchymal transitions, expressed in progenitor cells of the developing endocrine pancreas

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Cdc42/N-WASP signaling links actin dynamics to pancreatic β cell delamination and differentiation

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

In vivo imaging of emerging endocrine cells reveals a requirement for PI3K-regulated motility in pancreatic islet morphogenesis.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Modeling Development and Disease with Organoids

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Organogenesis in a dish: modeling development and disease using organoid technologies

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Organoids: Modeling Development and the Stem Cell Niche in a Dish.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

The physics of organoids: a biophysical approach to understanding organogenesis.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Self-organizing optic-cup morphogenesis in three-dimensional culture

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Modeling mouse and human development using organoid cultures

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Organoids from adult liver and pancreas: Stem cell biology and biomedical utility

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Artificial three-dimensional niches deconstruct pancreas development in vitro.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Reconstituting pancreas development from purified progenitor cells reveals genes essential for islet differentiation

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Ex Vivo Expansion and Differentiation of Human and Mouse Fetal Pancreatic Progenitors Are Modulated by Epidermal Growth Factor

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Colony-forming cells in the adult mouse pancreas are expandable in Matrigel and form endocrine/acinar colonies in laminin hydrogel

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

In vitro multilineage differentiation and self-renewal of single pancreatic colony-forming cells from adult C57BL/6 mice.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

RAS Regulates the Transition from Naive to Primed Pluripotent Stem Cells

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

CRISPR-Cas systems for editing, regulating and targeting genomes

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Insulin production by human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Differentiated human stem cells resemble fetal, not adult, β cells

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Diffusion pseudotime robustly reconstructs lineage branching

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Using single-cell genomics to understand developmental processes and cell fate decisions.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Single-Cell Gene Expression Analysis of a Human ESC Model of Pancreatic Endocrine Development Reveals Different Paths to β-Cell Differentiation

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Efficient Generation of Glucose-Responsive Beta Cells from Isolated GP2 Human Pancreatic Progenitors.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Intraocular in vivo imaging of pancreatic islet cell physiology/pathology

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Pancreatic islet plasticity: interspecies comparison of islet architecture and composition

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

The Role of Pancreatic Preproglucagon in Glucose Homeostasis in Mice

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Mechanisms of Action and Therapeutic Application of Glucagon-like Peptide-1

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Role of transcription factors in the transdifferentiation of pancreatic islet cells.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Endothelial cells control pancreatic cell fate at defined stages through EGFL7 signaling

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Signals in the pancreatic islet microenvironment influence β-cell proliferation.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Multilineage communication regulates human liver bud development from pluripotency.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Genome-wide analysis of PDX1 target genes in human pancreatic progenitors

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

iPSC technology-based regenerative therapy for diabetes.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Dissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing tools

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Genetic insulin resistance is a potent regulator of gene expression and proliferation in human iPS cells

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

GATA6 Plays an Important Role in the Induction of Human Definitive Endoderm, Development of the Pancreas, and Functionality of Pancreatic β Cells.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

GATA4 and GATA6 control mouse pancreas organogenesis.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

β-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Permanent neonatal diabetes due to mutations in KCNJ11 encoding Kir6.2: patient characteristics and initial response to sulfonylurea therapy

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Reestablishment of Glucose Inhibition of Glucagon Secretion in Small Pseudoislets

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Spontaneous reassociation of dispersed adult rat pancreatic islet cells into aggregates with three-dimensional architecture typical of native islets

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Using pancreas tissue slices for in situ studies of islet of Langerhans and acinar cell biology

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Noninvasive in vivo imaging of pancreatic islet cell biology

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

A genetically engineered human pancreatic β cell line exhibiting glucose-inducible insulin secretion

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Development of a conditionally immortalized human pancreatic β cell line.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

A human beta cell line with drug inducible excision of immortalizing transgenes

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

MANF protects human pancreatic beta cells against stress-induced cell death

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Modeling human pancreatic beta cell dedifferentiation.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Aggregation of Engineered Human β-Cells Into Pseudoislets: Insulin Secretion and Gene Expression Profile in Normoxic and Hypoxic Milieu

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Endothelial and beta cell composite aggregates for improved function of a bioartificial pancreas encapsulation device

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Culturing pancreatic islets in microfluidic flow enhances morphology of the associated endothelial cells

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Stem cell niche engineering through droplet microfluidics

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Microfluidic organs-on-chips

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Organs-on-a-Chip: A Fast Track for Engineered Human Tissues in Drug Development

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Endocrine system on chip for a diabetes treatment model

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

In Situ Patterning of Microfluidic Networks in 3D Cell-Laden Hydrogels

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

A microfluidic device designed to induce media flow throughout pancreatic islets while limiting shear-induced damage.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Microfluidic device for multimodal characterization of pancreatic islets

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Systematic single-cell analysis provides new insights into heterogeneity and plasticity of the pancreas.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

The use of animal models in diabetes research

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Streptozotocin-induced diabetes in large animals (pigs/primates): role of GLUT2 transporter and beta-cell plasticity

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Animal models of obesity and diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Novel canine models of obese prediabetes and mild type 2 diabetes

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Feline models of type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Diabetes mellitus in Macaca mulatta monkeys is characterised by islet amyloidosis and reduction in beta-cell population

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Old world nonhuman primate models of type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Metabolic syndrome and extensive adipose tissue inflammation in morbidly obese Göttingen minipigs

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Swine models of type 2 diabetes mellitus: insulin resistance, glucose tolerance, and cardiovascular complications

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Principles of early human development and germ cell program from conserved model systems

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

INS-eGFP transgenic pigs: a novel reporter system for studying maturation, growth and vascularisation of neonatal islet-like cell clusters.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Dominant-negative mutant hepatocyte nuclear factor 1alpha induces diabetes in transgenic-cloned pigs

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Permanent neonatal diabetes in INS(C94Y) transgenic pigs.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Favorable outcome of experimental islet xenotransplantation without immunosuppression in a nonhuman primate model of diabetes

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Porcine Islet Xenografts: a Clinical Source of ß-Cell Grafts

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Interspecies Chimerism with Mammalian Pluripotent Stem Cells.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Interspecies chimeric complementation for the generation of functional human tissues and organs in large animal hosts

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Interspecies organogenesis generates autologous functional islets.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Blastocyst complementation generates exogenic pancreas in vivo in apancreatic cloned pigs

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Generation of Rat Pancreas in Mouse by Interspecific Blastocyst Injection of Pluripotent Stem Cells

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Large scale isolation, growth, and function of porcine neonatal islet cells

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Pseudotemporal Ordering of Single Cells Reveals Metabolic Control of Postnatal β Cell Proliferation.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Deciphering Pancreatic Islet β Cell and α Cell Maturation Pathways and Characteristic Features at the Single-Cell Level

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Genetically engineered pig models for diabetes research

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Glucose intolerance and reduced proliferation of pancreatic beta-cells in transgenic pigs with impaired glucose-dependent insulinotropic polypeptide function

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

INS-gene mutations: from genetics and beta cell biology to clinical disease

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Reduced Insulin Production Relieves Endoplasmic Reticulum Stress and Induces β Cell Proliferation

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

ER stress as a trigger for β-cell dysfunction and autoimmunity in type 1 diabetes

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Multiplex target protein imaging in tissue sections by mass spectrometry--TAMSIM.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Single cell-resolution western blotting.

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Vertebrate endoderm development

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Immunohistochemistry of pancreatic development in cattle and pig

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Beta cell differentiation during early human pancreas development

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Islet architecture: A comparative study

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Pancreatic-polypeptide-rich regions in human pancreas

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

Unique arrangement of alpha- and beta-cells in human islets of Langerhans

1 reference

https://api.crossref.org/works/10.1038/S41574-018-0132-Z

7 January 2021

10.1038/S41574-018-0132-Z

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30504925 AND SRC:MED&resulttype=core&format=json

10 April 2020

1 reference