Identification of C10 nitrogen-containing aporphines with dopamine D1 versus D5 receptor selectivity (Q89925433)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32107165 AND SRC:MED&resulttype=core&format=json

9 April 2020

title

Identification of C10 nitrogen-containing aporphines with dopamine D1 versus D5 receptor selectivity (English)

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9 April 2020

author name string

Anupam Karki

1

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9 April 2020

Reecan Juarez

2

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9 April 2020

Hari K Namballa

3

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9 April 2020

Ian Alberts

4

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9 April 2020

Wayne W Harding

5

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9 April 2020

publication date

20 February 2020

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Bioorganic & Medicinal Chemistry Letters

9 April 2020

published in

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9 April 2020

volume

30

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9 April 2020

issue

8

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9 April 2020

page(s)

127053

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Differential effects of D1 and D2 dopamine agonists on stereotyped locomotion in rats

9 April 2020

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Evaluation of structural effects on 5-HT(2A) receptor antagonism by aporphines: identification of a new aporphine with 5-HT(2A) antagonist activity.

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(6aR)-11-amino-N-propyl-noraporphine, a new dopamine D2 and serotonin 5-HT1A dual agonist, elicits potent antiparkinsonian action and attenuates levodopa-induced dyskinesia in a 6-OHDA-lesioned rat model of Parkinson's disease.

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