Mechanisms of Testicular Disruption from Exposure to Bisphenol A and Phtalates (Q89660166)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32046352 AND SRC:MED&resulttype=core&format=json

7 April 2020

review article

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title

Mechanisms of Testicular Disruption from Exposure to Bisphenol A and Phtalates (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32046352 AND SRC:MED&resulttype=core&format=json

7 April 2020

author name string

Francesco Pallotti

1

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7 April 2020

Marianna Pelloni

2

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7 April 2020

Daniele Gianfrilli

3

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7 April 2020

Andrea Lenzi

4

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7 April 2020

Francesco Lombardo

5

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7 April 2020

Donatella Paoli

6

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7 April 2020

publication date

8 February 2020

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Journal of Clinical Medicine

7 April 2020

published in

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7 April 2020

volume

9

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7 April 2020

issue

2

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Creative Commons Attribution 4.0 International

7 April 2020

copyright license

start time

8 February 2020

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April 2022 Public Data File from Crossref

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1 reference

12 December 2020

Comparative effects of neonatal exposure of male rats to potent and weak (environmental) estrogens on spermatogenesis at puberty and the relationship to adult testis size and fertility: evidence for stimulatory effects of low estrogen levels

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12 December 2020

Large effects from small exposures. I. Mechanisms for endocrine-disrupting chemicals with estrogenic activity

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Human 'testicular dysgenesis syndrome': a possible model using in-utero exposure of the rat to dibutyl phthalate

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Phthalate ester-induced gubernacular lesions are associated with reduced insl3 gene expression in the fetal rat testis

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Differential effects of phthalate esters on transcriptional activities via human estrogen receptors alpha and beta, and androgen receptor

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White adipose tissue: storage and effector site for environmental pollutants.

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Study on developmental abnormalities in hypospadiac male rats induced by maternal exposure to di-n-butyl phthalate (DBP).

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Cumulative effects of dibutyl phthalate and diethylhexyl phthalate on male rat reproductive tract development: altered fetal steroid hormones and genes

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Involvement of testicular growth factors in fetal Leydig cell aggregation after exposure to phthalate in utero

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Mechanisms of action of phthalate esters, individually and in combination, to induce abnormal reproductive development in male laboratory rats

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Urinary metabolites of di(2-ethylhexyl) phthalate are associated with decreased steroid hormone levels in adult men.

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Phthalates impair germ cell development in the human fetal testis in vitro without change in testosterone production.

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Medications as a potential source of exposure to phthalates in the U.S. population

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Molecular and toxicologic research in newborn hypospadiac male rats following in utero exposure to di-n-butyl phthalate (DBP)

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Bisphenol A may cause testosterone reduction by adversely affecting both testis and pituitary systems similar to estradiol.

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Effect of perinatal and postnatal bisphenol A exposure to the regulatory circuits at the hypothalamus-pituitary-gonadal axis of CD-1 mice.

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Molecular changes induced by bisphenol-A in rat Sertoli cell culture

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In vitro effects of estradiol-17β, monobutyl phthalate and mono-(2-ethylhexyl) phthalate on the secretion of testosterone and insulin-like peptide 3 by interstitial cells of scrotal and retained testes in dogs.

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Bisphenol-A acts as a potent estrogen via non-classical estrogen triggered pathways

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Antiandrogenic activity of phthalate mixtures: Validity of concentration addition

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Endocrine disrupting chemicals: Multiple effects on testicular signaling and spermatogenesis

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Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses

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Phthalate excretion pattern and testicular function: a study of 881 healthy Danish men

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Differential effects of bisphenol A and diethylstilbestrol on human, rat and mouse fetal leydig cell function

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Effects of maternal exposure to phthalates and bisphenol A during pregnancy on gestational age.

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Urinary phthalate metabolites and male reproductive function parameters in Chongqing general population, China.

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12 December 2020

Are urinary bisphenol A levels in men related to semen quality and embryo development after medically assisted reproduction?

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12 December 2020

Fetal programming of adult Leydig cell function by androgenic effects on stem/progenitor cells

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Urinary bisphenol A levels in young men: association with reproductive hormones and semen quality

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12 December 2020

Persistent organic pollutant levels in human visceral and subcutaneous adipose tissue in obese individuals--depot differences and dysmetabolism implications

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Phthalates, perfluoroalkyl acids, metals and organochlorines and reproductive function: a multipollutant assessment in Greenlandic, Polish and Ukrainian men.

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Inutero exposure to diisononyl phthalate caused testicular dysgenesis of rat fetal testis

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12 December 2020

A negative correlation between insulin-like peptide 3 and bisphenol A in human cord blood suggests an effect of endocrine disruptors on testicular descent during fetal development

1 reference

12 December 2020

Adult exposure to bisphenol A (BPA) in Wistar rats reduces sperm quality with disruption of the hypothalamic-pituitary-testicular axis

1 reference

12 December 2020

Dibutyl phthalate induces oxidative stress and impairs spermatogenesis in adult rats.

1 reference

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Influence of in utero di-n-hexyl phthalate and dicyclohexyl phthalate on fetal testicular development in rats.

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An investigation of the endocrine-disruptive effects of bisphenol a in human and rat fetal testes

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Bisphenol-A affects male fertility via fertility-related proteins in spermatozoa.

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Estrogenic endocrine disruptors: Molecular mechanisms of action

1 reference

12 December 2020

Bisphenol A environmental exposure and the detrimental effects on human metabolic health: is it necessary to revise the risk assessment in vulnerable population?

1 reference

12 December 2020

A review on endocrine disruptors and their possible impacts on human health.

1 reference

12 December 2020

Associations between Maternal Biomarkers of Phthalate Exposure and Inflammation Using Repeated Measurements across Pregnancy

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12 December 2020

Phthalate exposure and reproductive parameters in young men from the general Swedish population.

1 reference

12 December 2020

Cumulative Chemical Exposures During Pregnancy and Early Development

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12 December 2020

Executive Summary to EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals.

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12 December 2020

Mono-(2-ethylhexyl) phthalate (MEHP) affects intercellular junctions of Sertoli cell: A potential role of oxidative stress

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12 December 2020

The non-genomic effects of endocrine-disrupting chemicals on mammalian sperm.

1 reference

12 December 2020

Phthalate exposure and semen quality in fertile US men.

1 reference

12 December 2020

Phthalate exposure in association with serum hormone levels, sperm DNA damage and spermatozoa apoptosis: A cross-sectional study in China

1 reference

12 December 2020

Semen phthalate metabolites, semen quality parameters and serum reproductive hormones: A cross-sectional study in China

1 reference

12 December 2020

Icam5 Expression Exhibits Sex Differences in the Neonatal Pituitary and Is Regulated by Estradiol and Bisphenol A

1 reference

12 December 2020

Effects of in Utero Exposure to Dicyclohexyl Phthalate on Rat Fetal Leydig Cells

1 reference

12 December 2020

Spermatogenesis in humans and its affecting factors

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Di-(2-ethylhexyl) phthalate inhibits testosterone level through disturbed hypothalamic-pituitary-testis axis and ERK-mediated 5α-Reductase 2.

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First trimester phthalate exposure and male newborn genital anomalies

1 reference

12 December 2020

The epidemiologic evidence linking prenatal and postnatal exposure to endocrine disrupting chemicals with male reproductive disorders: a systematic review and meta-analysis

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Prenatal Exposure to DEHP Induces Premature Reproductive Senescence in Male Mice.

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Effects of six priority controlled phthalate esters with long-term low-dose integrated exposure on male reproductive toxicity in rats.

1 reference

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Bisphenol A Exposure during Pregnancy Alters the Mortality and Levels of Reproductive Hormones and Genes in Offspring Mice.

1 reference

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Phthalate exposure, even below US EPA reference doses, was associated with semen quality and reproductive hormones: Prospective MARHCS study in general population

1 reference

12 December 2020

Parallel assessment of the effects of bisphenol A and several of its analogs on the adult human testis

1 reference

12 December 2020

Dibutyl phthalate induced testicular dysgenesis originates after seminiferous cord formation in rats

1 reference

12 December 2020

Agonistic and antagonistic effects of phthalates and their urinary metabolites on the steroid hormone receptors ERα, ERβ, and AR.

1 reference

12 December 2020

Anti-androgenic mechanisms of Bisphenol A involve androgen receptor signaling pathway

1 reference

12 December 2020

Di-n-butyl phthalate prompts interruption of spermatogenesis, steroidogenesis, and fertility associated with increased testicular oxidative stress in adult male rats

1 reference

12 December 2020

Endocrine Disruption in Human Fetal Testis Explants by Individual and Combined Exposures to Selected Pharmaceuticals, Pesticides, and Environmental Pollutants

1 reference

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Phthalate metabolites related to infertile biomarkers and infertility in Chinese men.

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Bisphenol A Exposure Impairs Epididymal Development during the Peripubertal Period of Rats: Inflammatory Profile and Tissue Changes

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A role of low dose chemical mixtures in adipose tissue in carcinogenesis

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Effects of Exposure to the Endocrine-Disrupting Chemical Bisphenol A During Critical Windows of Murine Pituitary Development

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Endocrine disruptors: Revisiting concepts and dogma in toxicology

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Urinary bisphenol A concentrations are associated with reproductive parameters in young men.

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Bisphenol A (BPA) and cell signaling pathways.

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In utero combined di-(2-ethylhexyl) phthalate and diethyl phthalate exposure cumulatively impairs rat fetal Leydig cell development

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Evidence of the Possible Harm of Endocrine-Disrupting Chemicals in Humans: Ongoing Debates and Key Issues.

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Effects of continuous bisphenol A exposure from early gestation on 90 day old rat testes function and sperm molecular profiles: A CLARITY-BPA consortium study.

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Prenatal Exposure to Bisphenol A Analogues on Male Reproductive Functions in Mice

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Alteration in apoptotic rate of testicular cells and sperms following administration of Bisphenol A (BPA) in Wistar albino rats

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The Possible Impact of Antenatal Exposure to Ubiquitous Phthalates Upon Male Reproductive Function at 20 Years of Age.

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Mixed "Antiandrogenic" Chemicals at Low Individual Doses Produce Reproductive Tract Malformations in the Male Rat

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First Trimester Urinary Bisphenol and Phthalate Concentrations and Time to Pregnancy: A Population-Based Cohort Analysis

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Effects of folic acid on testicular toxicity induced by bisphenol-A in male Wistar rats

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12 December 2020

Impact of low-dose chronic exposure to bisphenol A and its analogue bisphenol B, bisphenol F and bisphenol S on hypothalamo-pituitary-testicular activities in adult rats: A focus on the possible hormonal mode of action

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The Seveso accident: A look at 40 years of health research and beyond

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Decreased Capacity for Sperm Production Induced by Perinatal Bisphenol A Exposure Is Associated with an Increased Inflammatory Response in the Offspring of C57BL/6 Male Mice

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Exposure of environmental Bisphenol A in relation to routine sperm parameters and sperm movement characteristics among fertile men

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In utero exposure to bisphenol A disrupts fetal testis development in rats

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New approaches to cope with possible harms of low-dose environmental chemicals

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The relationships between urinary phthalate metabolites, reproductive hormones and semen parameters in men attending in vitro fertilization clinic

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Phthalates and Phthalate Alternatives Have Diverse Associations with Oxidative Stress and Inflammation in Pregnant Women

1 reference

12 December 2020

Prenatal exposure to an environmentally relevant phthalate mixture disrupts testicular steroidogenesis in adult male mice

1 reference

12 December 2020

Body fluid concentrations of bisphenol A and their association with in vitro fertilization outcomes

1 reference

12 December 2020

Maternal exposure to bisphenol A during pregnancy interferes testis development of F1 male mice.

1 reference

12 December 2020

Male exposure to bisphenol A (BPA) and semen quality in the Home Observation of Periconceptional Exposures (HOPE) cohort

1 reference

12 December 2020

Prenatal BPA and its analogs BPB, BPF, and BPS exposure and reproductive axis function in the male offspring of Sprague Dawley rats

1 reference

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Which chemicals should be grouped together for mixture risk assessments of male reproductive disorders?

1 reference

12 December 2020

Identifiers

DOI

10.3390/JCM9020471

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32046352 AND SRC:MED&resulttype=core&format=json

7 April 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32046352 AND SRC:MED&resulttype=core&format=json

7 April 2020

PubMed publication ID

32046352

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