Detection of EXP1-Specific CD4 T Cell Responses Directed Against a Broad Range of Epitopes Including Two Promiscuous MHC Class II Binders During Acute Plasmodium falciparum Malaria (Q89621117)

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scientific article published on 01 January 2019

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English	Detection of EXP1-Specific CD4 T Cell Responses Directed Against a Broad Range of Epitopes Including Two Promiscuous MHC Class II Binders During Acute Plasmodium falciparum Malaria	scientific article published on 01 January 2019

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Detection of EXP1-Specific CD4 T Cell Responses Directed Against a Broad Range of Epitopes Including Two Promiscuous MHC Class II Binders During Acute Plasmodium falciparum Malaria (English)

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Plasmodium falciparum

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Plasmodium falciparum malaria

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John Sidney

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Alessandro Sette

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Julian Schulze zur Wiesch

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Christin Ackermann

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Matthias Marget

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Matthias Marget

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Nils H Wildner

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Melanie Wittner

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Thomas Jacobs

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1 January 2019

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Frontiers in Immunology

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Creative Commons Attribution 4.0 International

22 January 2020

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Molecular analysis of the association of HLA-B53 and resistance to severe malaria

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Rationale for development of a synthetic vaccine against plasmodium falciparum malaria

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A blood stage antigen of Plasmodium falciparum shares determinants with the sporozoite coat protein

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A malaria protein exported into a new compartment within the host erythrocyte.

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Inhibitory monoclonal antibody against a (myristylated) small-molecular-weight antigen from Plasmodium falciparum associated with the parasitophorous vacuole membrane

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Plasmodium yoelii: 17-kDa hepatic and erythrocytic stage protein is the target of an inhibitory monoclonal antibody

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Analysis of human T cell clones specific for conserved peptide sequences within malaria proteins: Paucity of clones responsive to intact parasites

1 reference

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Identification and characterization of the protective hepatocyte erythrocyte protein 17 kDa gene of Plasmodium yoelii, homolog of Plasmodium falciparum exported protein 1.

1 reference

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Degenerate Cytotoxic T Cell Epitopes from P. falciparum Restricted by Multiple HLA-A and HLA-B Supertype Alleles

1 reference

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12 December 2020

based on heuristic

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Several common HLA-DR types share largely overlapping peptide binding repertoires

1 reference

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High antigen density and IL-2 are required for generation of CD4 effectors secreting Th1 rather than Th0 cytokines.

1 reference

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12 December 2020

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CD4( ) T-cell- and gamma interferon-dependent protection against murine malaria by immunization with linear synthetic peptides from a Plasmodium yoelii 17-kilodalton hepatocyte erythrocyte protein.

1 reference

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12 December 2020

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Cytotoxic T-lymphocyte epitopes for HLA-B53 and other HLA types in the malaria vaccine candidate liver-stage antigen 3

1 reference

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HLA-DR-promiscuous T cell epitopes from Plasmodium falciparum pre-erythrocytic-stage antigens restricted by multiple HLA class II alleles

1 reference

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HLA-A*0201 restricted CD8 T-lymphocyte responses to malaria: identification of new Plasmodium falciparum epitopes by IFN-gamma ELISPOT.

1 reference

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Recognition of synthetic polypeptides corresponding to the N- and C-terminal fragments of Plasmodium falciparum Exp-1 by T-cells and plasma from human donors from African endemic areas

1 reference

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Comprehensive Analysis of CD8 -T-Cell Responses against Hepatitis C Virus Reveals Multiple Unpredicted Specificities

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Malaria blood stage suppression of liver stage immunity by dendritic cells

1 reference

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Comparison of overlapping peptide sets for detection of antiviral CD8 and CD4 T cell responses

1 reference

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Reliable prediction of T-cell epitopes using neural networks with novel sequence representations

1 reference

https://pubmed.ncbi.nlm.nih.gov/32038611

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T-cell epitope mapping using the ELISPOT approach

1 reference

https://pubmed.ncbi.nlm.nih.gov/32038611

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Identification of Plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data

1 reference

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Progress in defining CD4 helper cell responses in chronic viral infections

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Innate immunity to malaria

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Quantitative proteomics of the human malaria parasite Plasmodium falciparum and its application to studies of development and inhibition

1 reference

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The magnitude and breadth of hepatitis C virus-specific CD8 T cells depend on absolute CD4 T-cell count in individuals coinfected with HIV-1.

1 reference

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Boosting of DNA vaccine-elicited gamma interferon responses in humans by exposure to malaria parasites

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Generating quantitative models describing the sequence specificity of biological processes with the stabilized matrix method

1 reference

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Broad repertoire of the CD4 Th cell response in spontaneously controlled hepatitis C virus infection includes dominant and highly promiscuous epitopes

1 reference

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Organization of ETRAMPs and EXP-1 at the parasite-host cell interface of malaria parasites

1 reference

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CD8 T lymphocytes protective against malaria liver stages are primed in skin-draining lymph nodes.

1 reference

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A systematic assessment of MHC class II peptide binding predictions and evaluation of a consensus approach

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NetMHC-3.0: accurate web accessible predictions of human, mouse and monkey MHC class I affinities for peptides of length 8-11

1 reference

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The N-terminal domain of Plasmodium falciparum circumsporozoite protein represents a target of protective immunity

1 reference

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Five HLA-DP molecules frequently expressed in the worldwide human population share a common HLA supertypic binding specificity

1 reference

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Molecular determinants of T cell epitope recognition to the common Timothy grass allergen

1 reference

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Identification and localization of minimal MHC-restricted CD8 T cell epitopes within the Plasmodium falciparum AMA1 protein

1 reference

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12 December 2020

based on heuristic

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Divergent Motifs but Overlapping Binding Repertoires of Six HLA-DQ Molecules Frequently Expressed in the Worldwide Human Population

1 reference

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Peptide binding predictions for HLA DR, DP and DQ molecules

1 reference

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Development of an interferon-gamma ELISPOT assay to detect human T cell responses to HSV-2

1 reference

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Live Attenuated Malaria Vaccine Designed to Protect Through Hepatic CD8 T Cell Immunity

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Broadly directed virus-specific CD4 T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence

1 reference

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Immune epitope database analysis resource

1 reference

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Molecular make-up of the Plasmodium parasitophorous vacuolar membrane

1 reference

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based on heuristic

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Full-length Plasmodium falciparum circumsporozoite protein administered with long-chain poly(I·C) or the Toll-like receptor 4 agonist glucopyranosyl lipid adjuvant-stable emulsion elicits potent antibody and CD4 T cell immunity and protection in mi

1 reference

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Memory T cells in latent Mycobacterium tuberculosis infection are directed against three antigenic islands and largely contained in a CXCR3 CCR6 Th1 subset

1 reference

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Measurement of MHC/peptide interactions by gel filtration or monoclonal antibody capture

1 reference

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based on heuristic

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1 reference

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1 reference

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1 reference

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1 reference

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based on heuristic

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1 reference

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Measurement of ex vivo ELISpot interferon-gamma recall responses to Plasmodium falciparum AMA1 and CSP in Ghanaian adults with natural exposure to malaria

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Association between HLA genes and dust mite sensitivity in a Brazilian population

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blood Stage Malaria Disrupts Humoral Immunity to the Pre-erythrocytic Stage Circumsporozoite Protein

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasmodium berghei EXP-1 interacts with host Apolipoprotein H during Plasmodium liver-stage development.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global Assessment of Dengue Virus-Specific CD4 T Cell Responses in Dengue-Endemic Areas

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasmodium falciparum Exported Protein 1 is localized to dense granules in merozoites

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of a broad range of low level MHC class II-restricted Hepatitis Delta Virus (HDV)-specific T cell responses regardless of the clinical status

1 reference

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Malaria prevention: from immunological concepts to effective vaccines and protective antibodies

1 reference

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NK1.1 Expression Defines a Population of CD4 Effector T Cells Displaying Th1 and Tfh Cell Properties That Support Early Antibody Production During Infection

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

UniProt: a worldwide hub of protein knowledge

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growing evidence of Plasmodium vivax across malaria-endemic Africa

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comprehensive Review of Human -Specific CD8 T Cell Epitopes

1 reference

https://pubmed.ncbi.nlm.nih.gov/32038611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of B Cell Memory in Malaria

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional Comparison of Blood-Stage Plasmodium falciparum Malaria Vaccine Candidate Antigens.

1 reference

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Characterization of Magnitude and Antigen Specificity of HLA-DP, DQ, and DRB3/4/5 Restricted DENV-Specific CD4 T Cell Responses

1 reference

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10.3389/FIMMU.2019.03037

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7 April 2020

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7 April 2020

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7 April 2020

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