Taxol Induces Brk-dependent Prosurvival Phenotypes in TNBC Cells through an AhR/GR/HIF-driven Signaling Axis (Q89507021)

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5 April 2020

title

Taxol Induces Brk-dependent Prosurvival Phenotypes in TNBC Cells through an AhR/GR/HIF-driven Signaling Axis (English)

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5 April 2020

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Carlos Perez Kerkvliet

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John A Cidlowski

8

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Tiffany N Seagroves

11

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Julie H Ostrander

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Carol A Lange

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Kathryn L Schwertfeger

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Kathryn L Schwertfeger

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Tarah M. Regan Anderson

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Tarah M Regan Anderson

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author name string

Shihong Ma

2

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5 April 2020

Yan Peng

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Taylor M Helle

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Raisa I Krutilina

6

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Ganesh V Raj

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publication date

10 July 2018

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Molecular Cancer Research

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published in

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volume

16

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issue

11

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page(s)

1761-1772

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describes a project that uses

5 April 2020

ImageJ

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11 June 2022

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inferred from PubMed Central ID database lookup

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Brk activates rac1 and promotes cell migration and invasion by phosphorylating paxillin

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Overexpression of hypoxia-inducible factor HIF-1alpha predicts early relapse in breast cancer: retrospective study in a series of 745 patients

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Brk protects breast cancer cells from autophagic cell death induced by loss of anchorage.

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Ligand-Independent Phosphorylation of the Glucocorticoid Receptor Integrates Cellular Stress Pathways with Nuclear Receptor Signaling

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Brk/PTK6 sustains activated EGFR signaling through inhibiting EGFR degradation and transactivating EGFR

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Phosphorylated and sumoylation-deficient progesterone receptors drive proliferative gene signatures during breast cancer progression

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Decreased androgen receptor expression is associated with distant metastases in patients with androgen receptor-expressing triple-negative breast carcinoma.

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Brk/PTK6 cooperates with HER2 and Src in regulating breast cancer cell survival and epithelial-to-mesenchymal transition

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Breast tumor kinase (Brk/PTK6) is a mediator of hypoxia-associated breast cancer progression.

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HIF-1α-independent hypoxia-induced rapid PTK6 stabilization is associated with increased motility and invasion

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Hypoxia-inducible factor 1 mediates intermittent hypoxia-induced migration of human breast cancer MDA-MB-231 cells

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12 December 2020

10.1158/1541-7786.MCR-18-0410

Identifiers

DOI

1 reference

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5 April 2020

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5 April 2020

PubMed publication ID

29991529

1 reference