Liver regeneration requires Yap1-TGFβ-dependent epithelial-mesenchymal transition in hepatocytes (Q88664654)

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26 March 2020

title

Liver regeneration requires Yap1-TGFβ-dependent epithelial-mesenchymal transition in hepatocytes (English)

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4

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author name string

Seh-Hoon Oh

1

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26 March 2020

Marzena Swiderska-Syn

2

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Mark L Jewell

3

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Anna Mae Diehl

5

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publication date

23 May 2018

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26 March 2020

published in

Journal of Hepatology

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volume

69

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issue

2

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page(s)

359-367

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Cellular and molecular changes in the early stages of chemical hepatocarcinogenesis in the rat.

26 March 2020

cites work

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12 December 2020

Appearance of alpha-smooth-muscle-actin-positive cells in hepatic fibrosis

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Transforming growth factor beta mRNA increases during liver regeneration: a possible paracrine mechanism of growth regulation

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Optimized adeno-associated virus 8 produces hepatocyte-specific Cre-mediated recombination without toxicity or affecting liver regeneration.

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Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development

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Hepatoblast and mesenchymal cell-specific gene-expression in fetal rat liver and in cultured fetal rat liver cells

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Liver regeneration after partial hepatectomy: critical analysis of mechanistic dilemmas

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Hepatocytes do not undergo epithelial-mesenchymal transition in liver fibrosis in mice

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Evolving challenges in hepatic fibrosis

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The role of signaling pathways in the development and treatment of hepatocellular carcinoma

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Snail1 suppresses TGF-beta-induced apoptosis and is sufficient to trigger EMT in hepatocytes

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Epithelial–mesenchymal transition in chronic liver disease: Fibrogenesis or escape from death?

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Lineage tracing demonstrates no evidence of cholangiocyte epithelial-to-mesenchymal transition in murine models of hepatic fibrosis

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The Hippo superhighway: signaling crossroads converging on the Hippo/Yap pathway in stem cells and development

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Smoothened is a master regulator of adult liver repair

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A secreted disulfide catalyst controls extracellular matrix composition and function

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Activation of the transcription factor GLI1 by WNT signaling underlies the role of SULFATASE 2 as a regulator of tissue regeneration

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Myofibroblastic cells function as progenitors to regenerate murine livers after partial hepatectomy.

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The role of cirrhosis in the etiology of hepatocellular carcinoma

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Function of GATA factors in the adult mouse liver

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The transcription factor CREB has no non-redundant functions in hepatic glucose metabolism in mice

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Yap1 is required for endothelial to mesenchymal transition of the atrioventricular cushion.

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Dynamic alterations in Hippo signaling pathway and YAP activation during liver regeneration

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Hippo pathway activity influences liver cell fate

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Loss of α-catenin elicits a cholestatic response and impairs liver regeneration.

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The Hippo signaling pathway in liver regeneration and tumorigenesis.

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Global Gene Expression Changes in Liver Following Hepatocyte Nuclear Factor 4 alpha deletion in Adult Mice

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Modulation of the EMT/MET process by pyrrole-imidazole polyamide targeting human transforming growth factor-β1.

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Signaling in Fibrosis: TGF-β, WNT, and YAP/TAZ Converge

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Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice.

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Reversible Human TGF-β Signal Shifting between Tumor Suppression and Fibro-Carcinogenesis: Implications of Smad Phospho-Isoforms for Hepatic Epithelial-Mesenchymal Transitions

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YAP/TAZ Are Mechanoregulators of TGF-β-Smad Signaling and Renal Fibrogenesis.

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12 December 2020

Hedgehog regulates yes-associated protein 1 in regenerating mouse liver

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12 December 2020

Engineering EMT using 3D micro-scaffold to promote hepatic functions for drug hepatotoxicity evaluation.

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12 December 2020

Targeting Yes-associated Protein with Evolved Peptide Aptamers to Disrupt TGF-β Signaling Pathway: Therapeutic Implication for Bone Tumor

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Hepatostat: Liver regeneration and normal liver tissue maintenance

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Hippo Signaling in the Liver Regulates Organ Size, Cell Fate, and Carcinogenesis.

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The diagnosis and treatment of hepatocellular carcinoma

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12 December 2020

Hepatic stellate cells as key target in liver fibrosis

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Tg737 regulates epithelial-mesenchymal transition and cancer stem cell properties via a negative feedback circuit between Snail and HNF4α during liver stem cell malignant transformation

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12 December 2020

EMT/MET at the Crossroad of Stemness, Regeneration and Oncogenesis: The Ying-Yang Equilibrium Recapitulated in Cell Spheroids

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12 December 2020

Can a fibrotic liver afford epithelial-mesenchymal transition?

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12 December 2020

10.1016/J.JHEP.2018.05.008

Identifiers

DOI

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26 March 2020

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PubMed publication ID

29758331

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